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      • Partial linear regression of compositional data

        Han Hyebin,Yu Kyusang 한국통계학회 2022 Journal of the Korean Statistical Society Vol.51 No.4

        We study a partial linear model in which the response is compositional and the predictors include both compositional and Euclidean variables. We define a partial linear regression model under Aitchison geometry based on isometric log-ratio (ilr) transformation. An identification condition of linear parameters is provided in terms of expectations and conditional expectations of the response and covariates. An estimator based on the identification is developed and asymptotic properties of proposed estimators are derived. The proposed method can be implemented easily by using existing R packages such as np and compositions. The limiting distribution of the proposed estimator is provided with normal distribution in Euclidean space so that it is easy to use for inference. Also, some finite sample properties are presented via simulation studies. We also present election data as an illustrative example.

      • Impact of nursing professionalism and communication skills on major satisfaction of nursing students

        Hyejoo Kim,Seungyoun Kim,Hyebin Kim,Mihyun Bae,Eunbi Ahn,Jiyeon Yu,Seonghyeon Heo,Jiwon An 한국성인간호학회 2021 성인간호학회 학술대회 Vol.2021 No.8

        Aim(s): The purpose of this study was to identify the impact of nursing professionalism and communication skills on major satisfaction of nursing students. Method(s): Data were collected from April 19 to September 2, 2020 for 139 first- and third- year nursing students at K university in Chungcheongbuk-do. Data analysis was performed by descriptive analysis, t-test, ANOVA, scheffe’s test and correlation coefficient using the SPSS 21.0 program. Result(s): The major satisfaction was significantly higher in the first year nursing students than the third year students, and in the nursing students without clinical experience than those with clinical experience. There were significant correlation between all variables. Major satisfaction was significantly correlated with nursing professionalism (r=.479, p<.001) and communication skills (r=.391, p<.001). There was a significant correlation between nursing professionalism and communication skills(r=.430, p<.001). Conclusion(s): A nursing education program that enhances nursing professionalism and communication skills is needed to improve major satisfaction. The results of this study showed that major satisfaction decreased after experiencing clinical practice. Therefore, further research on the stress of clinical practice and satisfaction with the major is needed.

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        Clinical outcomes of stereotactic body radiotherapy for spinal metastases from hepatocellular carcinoma

        Eonju Lee,Tae Gyu Kim,Hee Chul Park,Jeong Il Yu,Do Hoon Lim,Heerim Nam,Hyebin Lee,Joon Hyeok Lee 대한방사선종양학회 2015 Radiation Oncology Journal Vol.33 No.3

        Purpose: To investigate the outcomes of patients with spinal metastases from hepatocellular carcinoma (HCC), who were treated by stereotactic body radiotherapy (SBRT). Materials and Methods: This retrospective study evaluated 23 patients who underwent SBRT from October 2008 to August 2012 for 36 spinal metastases from HCC. SBRT consisted of approximately 2 fractionation schedules, which were 18 to 40 Gy in 1 to 4 fractions for group A lesions (n = 15) and 50 Gy in 10 fractions for group B lesions (n = 21). Results: The median follow-up period was 7 months (range, 2 to 16 months). Seven patients developed grade 1 or 2 gastrointestinal toxicity, and one developed grade 2 leucopenia. Compression fractures occurred in association with 25% of the lesions, with a median time to fracture of 2 months. Pain relief occurred in 92.3% and 68.4% of group A and B lesions, respectively. Radiologic response (complete and partial response) occurred in 80.0% and 61.9% of group A and B lesions, respectively. The estimated 1-year spinal-tumor progression-free survival rate was 78.5%. The median overall survival period and 1-year overall survival rate were 9 months (range, 2 to 16 months) and 25.7%, respectively. Conclusion: SBRT for spinal metastases from HCC is well tolerated and effective at providing pain relief and radiologic response. Because compression fractures develop at a high rate following SBRT for spinal metastases from primary HCC, careful follow up of the patient is required

      • SCOPUSKCI등재

        Clinical outcomes of stereotactic body radiotherapy for spinal metastases from hepatocellular carcinoma

        Lee, Eonju,Kim, Tae Gyu,Park, Hee Chul,Yu, Jeong Il,Lim, Do Hoon,Nam, Heerim,Lee, Hyebin,Lee, Joon Hyeok The Korean Society for Radiation Oncology 2015 Radiation Oncology Journal Vol.33 No.3

        Purpose: To investigate the outcomes of patients with spinal metastases from hepatocellular carcinoma (HCC), who were treated by stereotactic body radiotherapy (SBRT). Materials and Methods: This retrospective study evaluated 23 patients who underwent SBRT from October 2008 to August 2012 for 36 spinal metastases from HCC. SBRT consisted of approximately 2 fractionation schedules, which were 18 to 40 Gy in 1 to 4 fractions for group A lesions (n = 15) and 50 Gy in 10 fractions for group B lesions (n = 21). Results: The median follow-up period was 7 months (range, 2 to 16 months). Seven patients developed grade 1 or 2 gastrointestinal toxicity, and one developed grade 2 leucopenia. Compression fractures occurred in association with 25% of the lesions, with a median time to fracture of 2 months. Pain relief occurred in 92.3% and 68.4% of group A and B lesions, respectively. Radiologic response (complete and partial response) occurred in 80.0% and 61.9% of group A and B lesions, respectively. The estimated 1-year spinal-tumor progression-free survival rate was 78.5%. The median overall survival period and 1-year overall survival rate were 9 months (range, 2 to 16 months) and 25.7%, respectively. Conclusion: SBRT for spinal metastases from HCC is well tolerated and effective at providing pain relief and radiologic response. Because compression fractures develop at a high rate following SBRT for spinal metastases from primary HCC, careful follow up of the patient is required.

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