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Filters Modeling of Real-Time Electromagnetic Transient Simulation in the Converter Station
Hui, Hui,Liu, Sige,Su, Jian 대한전기학회 2012 The Journal of International Council on Electrical Vol.2 No.4
In this paper, companion model method is applied to establish a basic filter model for electromagnetic transient simulation. Based on the requirements of real-time simulation in the converter station, this paper proposes a simplified filter model and analyzes the speed-up ratio for model optimization. Simulation result shows that under the presupposition of ensuring calculation accuracy, the simplified model can evidently improve the calculation efficiency and play an important role in the realization of real-time electromagnetic transient simulation in the converter station.
Factorable surfaces in 3-Minkowski space
Huihui Meng,Huili Liu 대한수학회 2009 대한수학회보 Vol.46 No.1
In this paper, we mainly discuss factorable surfaces in 3-dimensional Minkowski space and give classification of such surfaces whose mean curvature and Gauss curvature satisfy certain conditions. In this paper, we mainly discuss factorable surfaces in 3-dimensional Minkowski space and give classification of such surfaces whose mean curvature and Gauss curvature satisfy certain conditions.
KAT8/MOF-Mediated Anti-Cancer Mechanism of Gemcitabine in Human Bladder Cancer Cells
( Huihui Zhu ),( Yong Wang ),( Tao Wei ),( Xiaoming Zhao ),( Fuqiang Li ),( Yana Li ),( Fei Wang ),( Yong Cai ),( Jingji Jin ) 한국응용약물학회 2021 Biomolecules & Therapeutics(구 응용약물학회지) Vol.29 No.2
Histone acetylation is a well-characterized epigenetic modification controlled by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Imbalanced histone acetylation has been observed in many primary cancers. Therefore, efforts have been made to find drugs or small molecules such as HDAC inhibitors that can revert acetylation levels to normal in cancer cells. We observed dose-dependent reduction in the endogenous and exogenous protein expression levels of KAT8 (also known as human MOF), a member of the MYST family of HATs, and its corresponding histone acetylation at H4K5, H4K8, and H4K16 in chemotherapy drug gemcitabine (GEM)-exposed T24 bladder cancer (BLCA) cells. Interestingly, the reduction in MOF and histone H4 acetylation was inversely proportional to GEM-induced γH2AX, an indicator of chemotherapy drug effectiveness. Furthermore, pGL4-MOF-Luc reporter activities were significantly inhibited by GEM, thereby suggesting that GEM utilizes an MOF-mediated anti-BLCA mechanism of action. In the CCK-8, wound healing assays and Transwell® experiments, the additive effects on cell proliferation and migration were observed in the presence of exogenous MOF and GEM. In addition, the promoted cell sensitivity to GEM by exogenous MOF in BLCA cells was confirmed using an Annexin V-FITC/PI assay. Taken together, our results provide the theoretical basis for elucidating the anti-BLCA mechanism of GEM.
Application of an extended Bouc-Wen model for hysteretic behavior of the RC structure with SCEBs
Huihui Dong,Qiang Han,Xiuli Du 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.71 No.6
The reinforced concrete (RC) structures usually suffer large residual displacements under strong motions. The large residual displacements may substantially reduce the anti-seismic capacity of structures during the aftershock and increase the difficulty and cost of structural repair after an earthquake. To reduce the adverse residual displacement, several self-centering energy dissipation braces (SCEBs) have been proposed to be installed to the RC structures. To investigate the seismic responses of the RC structures with SCEBs under the earthquake excitation, an extended Bouc-Wen model with degradation and self-centering effects is developed in this study. The extended model realized by MATLAB/Simulink program is able to capture the hysteretic characteristics of the RC structures with SCEBs, such as the energy dissipation and the degradation, especially the self-centering effect. The predicted hysteretic behavior of the RC structures with SCEBs based on the extended model, which used the unscented Kalman filter (UKF) for parameter identification, is compared with the experimental results. Comparison results show that the predicted hysteretic curves can be in good agreement with the experimental results. The nonlinear dynamic analyses using the extended model are then carried out to explore the seismic performance of the RC structures with SCEBs. The analysis results demonstrate that the SCEB can effectively reduce the residual displacements of the RC structures, but slightly increase the acceleration.
FDU-12 Mesoporous Materials Detection Hg (Ⅱ) Ions by QCM
Huihui Lou,Chong Shen,Qun Xiang,Jiaqiang Xu,Tianjun Lou 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.8
Thiol-functionalized three-dimensional (3D) mesoporous silica FDU-12 and SBA-15 with ordered pore were prepared. All the obtained materials were characterized by small angle X-ray scattering (SAXS), transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Mesoporous silica FDU-12 (Fm3m) materials with various unit cell sizes, multifaceted pore were convenient for the interaction of subject and object; the 2D SBA-15 mesoporous silica materials with short and order pore channel were better than the traditional SBA-15 mesoporous silica, in which the pore channel can be used fully. 3D mesoporous silica FDU-12 is used as a sensing material to reconstruct QCM sensors to enhance the stability and this material is an ideal material to deal with heavy metal ions in water.