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- 저자 : Hoshide, Satoshi (검색결과 3 건)
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Kentaro Kondo,Takashi Hoshide 한국지질과학협의회 2022 Geosciences Journal Vol.26 No.2
The upper Kayaoka sheet in the Atsumi area, Northeast Japan, has an alkaline-basaltic composition. The modal olivine and Ni enrichment in the lower part of the sheet indicates the accumulation of early formed olivine crystals. Overall, the average aspect ratio of plagioclase increases from the central part of the sheet toward both the top and bottom margins. The average aspect ratios of plagioclase and calculated crystallisation times at each height of the sheet, except for the lowermost margin, are roughly plotted near the regression line drawn based on those from many sills in previous research. However, we observed that the average aspect ratios of plagioclase in some horizons of the central part of the sheet exhibit an offset from the regression line. The olivine analcite dolerite in the central part of the sheet is rich in zeolite amygdules and glassy mesostasis with a quench texture. These observations suggest that the cooling rate in the central part of the sheet was faster compared with assuming conductive cooling only. A plausible mechanism for the rapid cooling at the centre of the sheet is heat transport by the convection of seawater that has infiltrated the columnar joint.
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Target Blood Pressure in Patients with Diabetes: Asian Perspective
Kazuomi Kario,박성하,박창규,Qi-Fang Huang,Hao-min Cheng,Satoshi Hoshide,Ji-Guang Wang,Chen-Huan Chen 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.6
Recently, the Action to Control Cardiovascular Risk in Diabetes (ACCORD) blood pressure (BP) trial enrolled 4733 participants with type 2 diabetes and randomized them to a target systolic blood pressure (SBP) of less than 120 mm Hg or 140 mm Hg. Despitethe significant difference in the achieved SBP, there was no significant difference in the incidence of primary outcomes. Based on this evidence, the target SBP for diabetics has been revised in the majority of major guidelines. However, there is a steeper association between SBP and stroke in Asians than other ethnicities, with stroke being the leading cause of cardiovascular mortality. This suggests that target BP in the Asian region should be tailored towards prevention of stroke. In the ACCORD study, the intensive BP treatment was associated with significant reductions in both total stroke and non-fatal stroke. The results from the ACCORD study are supported by a subgroup analysis from the ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET) study, which showed that, in diabetic patients, the risk of stroke continues to decrease to a SBP value of 115 mm Hg with no evidence of J curve. As diabetes is highly associated with underlying coronary artery disease, there is a justified concern for adverse effects resulting from too much lowering of BP. In a post hoc analysis of 6400 diabetic subjectsenrolled in the International Verapamil SR-Trandolapril (INVEST) study, subjects with SBP of less than 110 mm Hg were associatedwith a significant increase in all-cause mortality. In the ONTARGET study, at any levels of achieved SBP, diastolic blood pressure (DBP) below 67 mm Hg was associated with increased risk for cardiovascular outcomes. As such, a prudent approach would be to target a SBP of 130–140 mm Hg and DBP of above 60 mm Hg in diabetics with coronary artery disease. In conclusion, hypertension, in association with diabetes, has been found to be significantly correlated with an elevated risk for cardiovascular events. As the association between stroke and BP is stronger in Asians, compared to other ethnicities, consideration should be given for a target BP of 130/80 mm Hg in Asians.
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Park, Sungha,Buranakitjaroen, Peera,Chen, Chen-Huan,Chia, Yook-Chin,Divinagracia, Romeo,Hoshide, Satoshi,Shin, Jinho,Siddique, Saulat,Sison, Jorge,Soenarta, Arieska Ann,Sogunuru, Guru Prasad,Tay, Jam Nature Publishing Group UK 2018 Journal of human hypertension Vol.32 No.4
<P>Hypertension is the leading cause of mortality throughout Asia. Home blood pressure monitoring has the potential to improve hypertension control and is a useful adjunct to conventional office blood pressure measurements due to its diagnostic accuracy and prognostic value in predicting cardiovascular outcomes. At present, there are no region-specific guidelines addressing the use of home blood pressure monitoring in Asia. Therefore, an expert panel was convened to address the use of home blood pressure monitoring and develop key recommendations to help guide clinical practice throughout the Asia region. The resulting recommendations support the use of home blood pressure monitoring with a validated device as an accurate adjunct for diagnosing hypertension and predicting cardiovascular outcome. Diagnosis and treatment of hypertension should still be guided by conventional office/clinic blood pressure measurements. The expert panel encourages the incorporation of home blood pressure monitoring into local clinical guidelines and offers practical recommendations to ensure continuity of care where a validated home blood pressure device is not available.</P>
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