The Clinical Implication of Non-Proteolytic EnzYme Activities in Stomach Cancer

Chang, HeeKyung,Choi, JongSoon KOSIN UNIVERSITY COLLEGE OF MEDICINE 2006 高神大學校 醫學部 論文集 Vol.21 No.1

Backgrounds : Beta-glucuronidase and lactic dehydrogenase are non-proteolytic enzymes related to the inflammation. In recent years there are a few reports that these 2 enzymes may be markers of gastric cancer. Material and Methods : The study was to observe whether the measurement of enzyme activity had any critical role in assessement of diagnostic value, beta-glucuronidase and lactic dehydrogenase activities in neoplastic tissue of stomach were compared with those in the gastric muosa of non-neoplastic antral and body area, which were obtained from products of gastrectomy of 27 cases. The enzyme immunoassay was used fro the estimate of the activity of enxymes. Results : The activity of enzymes was compared with each differentiation and metastasis of the tumor. beta-glucuronidase activity in tumor was higher that that of normal mucosa and activity of antral mucosa with intestinal metaplasia, and it was higher than that of body. Lactic dehydrogenase activity in tumor was similar to that in the antral mucosa with intestinal metaplasia, and it was higher than that in the body mucosa of stomach. There were no significant statistical difference of actvities of both enzymes between metastatic and non-metastatic groups(p>0.01). No significant correlation between activities of both enzymes was not seen in the tumor mass(r=0.347, p>0.05). Conclusions : These results support that enzyme activities of beta-glucuronidase and LDH in gastric tissues and tumor mass could reflect the histopathologic status of stomach and the assessment of the activity of enzymes may be of value in the identification of high-risk groups.

EFL Students; Perceptions on Synchronous English Text Chatting: Implications for Its Implementation

Heekyung Choi 한국멀티미디어언어교육학회 2004 멀티미디어 언어교육 Vol.7 No.2

Risk Assessment of Iron dichloride for Environment in OECD High Production Volume Chemicals Program

Heekyung Bae,Mi Kyoung Kim,Kyungsook Ahn,Yeonki Choi,Hyunju Koo,Hyun-Mi Kim,Kwang-Soo Choi,Myungjin Kim 환경독성보건학회 2005 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

Feasibility of fast non-local means noise reduction algorithm in magnetic resonance imaging using 1.5 and 3.0 T with diffusion-weighted image technique

Choi, Won Ho,Choi, Hye Ran,Seo, Eunsoo,Hwang, Jeewoo,Oh, Heekyung,Kim, Myeong Rae,Han, Su Rin,Kim, Min Seok,Kang, Seong-Hyeon,Lee, Youngjin Elsevier 2019 OPTIK -STUTTGART- Vol.183 No.-

<P><B>Abstract</B></P> <P>Magnetic resonance imaging (MRI) has many advantages and has developed various pulse sequences. In particular, the diffusion weighted image (DWI) technique is widely used because it can acquire images quickly during examination of stroke, through a proper adjustment of the diffusion-weighted gradient b-value. However, a setting with inappropriate b-value causes loss of image signal that increases the influence of noise. Therefore, in this study, we quantitatively evaluated image quality after applying a variety of algorithms to the image acquired by changing the b-value and the main magnetic field in the MRI device. To acquire the image, the phantom was self-produced with an acrylic panel and chicken breast. Wiener filter, total variation (TV), and our proposed fast non-local means (FNLM) noise reduction algorithms were applied to the image. Consequently, the signal intensity at a 3.0 T magnetic field increased by a factor 4.8 compared to a 1.5 T magnetic field. Moreover, the signal-to-noise ratio and contrast-to-noise ratio were highest with the FNLM algorithm, and the values increased by factors of 9.5 and 9.9 with a 1.5 T magnetic field and by factors of 9.9 and 5.0 with a 3.0 T magnetic field compared to the noise image, respectively. The result of time resolution, the Wiener filter appeared the finest value, but had no significant difference compared to FNLM algorithm. In conclusion, our results confirmed that the proposed FNLM noise reduction algorithm can acquire both improved image quality and high processing time in MRI imaging with the DWI technique.</P>

한국문학 번역에서 고찰하는 번역가 문체: 세 번역가에 대한 코퍼스 주도적 분석

최희경 ( Heekyung Choi ) 사단법인 아시아문화학술원 2020 인문사회 21 Vol.11 No.6

본 연구는 한국소설 번역 텍스트를 코퍼스 주도 접근법으로 분석하여 번역가의 문체를 고찰한다. 이를 위해 한국소설을 영어로 번역한 번역가 3명의 번역 텍스트와 그에 대응하는 원천 텍스트를 코퍼스로 구축하고 워드스미스와 코메트릭스를 활용하여 분석한다. 어휘, 통사, 결속성, 이독성 등 네개의 언어 및 담화 층위에서 12개 문체표지를 분석한 결과, 어휘 심상성, 접속사 등 대부분의 표지에서 번역가 간에 문체 차이가 발견되어 번역가별 고유 문체의 존재를 시사한다. 수동태, 이독성 등에서는 동일 번역가의 텍스트 간에도 편차가 확인되어 문체표지에 따라 번역가 개인의 문체가 원천 텍스트나 저자 문체의 영향으로 약화될 수도 있음을 보여준다. 본 연구는 실무번역가, 출판사, 연구자, 교육자, 학생 등 한국문학 번역의 여러 이해관계자에 유용한 함의를 제공한다는 데 그 의의를 둔다. This study aims to uncover traces of the translator’s style in translated Korean novels through a corpus-driven approach. To this end, translated texts by three Korean-to-English literary translators and their corresponding source texts were compiled into corpora for analysis drawing on linguistic analysis tools - WordSmith and Coh-Metrix. The corpus analysis was conducted for 12 style markers at four linguistic and discourse levels: word, syntax, cohesion, and readability. The findings reveal that variances between translators are found in most of the markers including words’ imagability and connectives, indicating that distinctive translator styles exist. Variances within each translator are also observed in such markers as passive voice and readability, implying that source texts or the author’s style may offset the power of the translator’s style. This study is expected to provide useful insights into the style of Korean literary translation to various stakeholders including translators, publishers, researchers, teachers, and students.

국민이 공감하는 법치주의 실현방안

최희경 ( Heekyung Choi ) 이화여자대학교 법학연구소 2015 法學論集 Vol.20 No.1

The rule of law embraces substantive and not merely procedural justice. The rule of law can earn the national consensus when it secures the fundamental rights of the people and protection from any infringement of rights through the judiciary branch by granting and controlling state power by law. All provisions of law must be fair and applied impartially in order to encourage the people to keep it. Also, it is necessary to guarantee people``s participation in the process of legislation and application. However, the rule of law is damaged if the people``s input is ignored in the process of enactment of law and the law is enacted solely for the interests of the National Assembly members or other certain groups or if the law is enacted in a hurry without sufficient observation and discussion. It is also damaged if the people cannot trust the arbitration of the judiciary branch in any disputes concerning the violation of basic rights by the state power as in this case the resolution would not be within the boundaries of law, but arbitrary. This study was conducted to discuss the issues of the rule of law in Korea in terms of legislative and judiciary areas. It particularly discussed the problems with the Increasing legislation by National Assembly members, unfair sentencing, or excessive limitations of appeals. It specifically discusses the problems with legislation notification system, public hearing system, and citizen participation trials system that are executed to increase civil participation in the legislative and judiciary areas. The rule of law should reflect the voices of the people, who build the foundation of state power, should be realized for the people. Now is the time to look for the right ways and make active efforts realize this.

Risk Assessment of Iron Dichloride for Human Health in OECD High Production Volume Chemicals Program

Yeonki Choi,Kyungsook Ahn,Heekyung Bae,Mi Kyoung Kim,Hyunju Koo,Hyun-Mi Kim,Kwang-Soo Choi,Myungjin Kim 환경독성보건학회 2005 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

덴마크 적극적 노동시장정책(ALMP)의 실용교육 기제 탐색 : 유연안전성 모형의 변환 사례

최희경 ( Choi Heekyung ) 한국스칸디나비아학회 2021 스칸디나비아 연구 Vol.27 No.-

본 연구는 노동시장 활성화의 주된 요인인 실용주의 교육의 특징과 운영 기제를 탐색한 것으로 덴마크의 적극적 노동시장정책(ALMP)을 사례로 분석했다. 유연안전성의 대표국인 덴마크는 구직자의 취업과 노동력의 원활한 이동에 전통적으로 사회보장제도의 지원을 중시했으나 최근 ALMP를 강조하고 있다. ALMP 프로그램에서는 교육과 훈련이 핵심인데 이 논문은 그 특징과 기제를 분석하여 결과를 모형으로 제시했다. 노동시장과 직접 연계되는 덴마크 직업교육훈련의 특징은 높은 현장성과 지역성이다. 덴마크는 북유럽에서 유일하게 도제식 전통을 교육제도로 보존하고 있고, 현장실무 비중이 직업교육훈련 프로그램의 50∼75%에 달한다. 또한 교육훈련 과정 전반에 노동조합과 사용자들이 공식적으로 참여하고 있다. 교육훈련의 기획과 실행에는 지역수요가 적극 반영되는데 지역별 노조지부와 사업체, 지방자치단체의 역할과 지역대학의 실용주의 패러다임이 함께 작용한 결과다. 한편 정규일반교육도 노동시장에 장기적이고 근본적으로 영향을 미친다. 초중등교육과정에서는 국가전략 차원으로 기업가정신을 교육하는 한편, 고등교육기관들은 ‘책임대학’ 패러다임을 바탕으로 지역의 혁신과 발전을 추진하고 있다. 한국은 높은 교육열과 대학 진학률에도 노동시장 활성화에 어려움을 겪고 있다. 덴마크 사례로부터 시장과 지역의 수요를 반영하는 직업교육훈련, 정규교육의 실용주의, 경제산업부문 주체들의 적극적인 협력 등을 정책적 제도적 시사점으로 고려할 수 있다. This study explores a learnfare mechanism to link practical education to labor market in Denmark, focusing on transformation of the Flexicurity Model with three components of flexible labor market, social security and Active Labor Market Policy (ALMP). Since 1990s, the basic axis of ‘the golden triangle’ has shifted from connecting social security and the labor market to linking ALMP and the labor market, a new critical factor being practical education. This manuscript attempts to examine the nature and the process of the ALMP and the educational systems to strengthen it. In Danish vocational education and training system (VET), one can witness remarkable, workable cooperation between labor market and educational system, with its programs pragmatically responding to local demand of innovation and development. Key components of the VET can be hands-on training with local flavor and active participation of stakeholders. The VET’s work-based education such as internship or on-the-job training amounts up to 50∼75% of the entire programs. Social partners in the programs, including trade unions, employers, and local authorities, have officially and/or informally been engaged in planning, implementing and auditing the training programs. Notably, the approach in general education emphasizing entrepreneurship for primary and secondary schoolers inspires their potential for future jobs. Additionally, the paradigm of ‘Responsible University’ contributes to innovation and development of regional labor market. The Danish experiences can provide lessons to Korea, which despite a high level of education struggles to vitalize labor market in sustainable terms. Long overdue, a methodical design for practice-oriented education system merits consideration in order to embrace real world demand from both market and localities.

도시재개발 지역 노인이 인식하는 재개발의 의미와 방향성에 대한 연구

최희경(Heekyung Choi) 한국사회정책학회 2022 한국사회정책 Vol.29 No.1

본 연구에서는 급변하는 도시의 지역사회 환경에 처한 도시재개발 지역 노인들이 인식하는 재개발의 의미와 지역사회 주민으로서 노인들이 지향하는 바람직한 도시재개발의 방향성을 살펴보았다. 이를 위해 부산광역시 재송동에서 20년 이상 거주한 5명의 노인 연구참여자들과 함께 포토보이스 프로그램과 개별 심층면접을 진행한 후 결과물을 분석하였다. 연구참여자들이 직접 촬영한 총 128장의 사진과 텍스트를 재개발의 의미와 바람직한 재개발의 방향성의 2개 범주로 나누었다. 재개발의 의미 범주에는 ‘사라졌으나 잊을 수 없는’, ‘얻은 것과 잃은 것’ 2개의 주제가 포함되었으며, 재개발의 방향성 범주에는 ‘동네 개성의 보존’, ‘번듯한 동네보다 안전한 동네’, ‘다양성과 포용성의 주민편의 시설’, ‘개발주체의 공공성과 주민참여’ 등 4개의 주제가 포함되었다. 재개발의 의미에서 경제적 가치보다 삶의 흔적과 기억의 중요성이 부각되었으며, 재개발의 방향성으로 지역 특성 및 공동체성 유지, 보행 안전을 비롯한 안전 증진, 주민 혜택과 참여 증대, 지역사회의 역사와 특성을 보존하고 전수하는 노인 역할의 중요성 등이 제시되었다. The study aims to analyse the perceptions of elders concerning meanings and future directions of urban redevelopment. Photovoice research method was adopted to emphasize elderly initiative participatory actions. 5 elders having resided more than 20 years in Jae-Song Dong, Haeundae restrict, Busan participated in the program and in-depth interviews. 6 themes under two main categories were derived from the analysis on 128 pictures taken by the participants, documented texts from the discussions and in-depth interviews, and letters written by the participants. ‘disappearing but unforgettable’ and ‘gain and loss’ were included in the category of meanings of redevelopment. ‘preserving community characteristics’, ‘safety rather than appearance’, ‘community facilities for diverse population’, and ‘public agency and civil participation’ were included in the category of directions of redevelopment. Several suggestions were made based on the opinions of elderly participants: preservation of historical characteristics of the community, increasing walk safety, promoting voluntary civil participation. The process and results of the study confirmed the possibility of elderly contribution on urban redevelopment, which meant the importance of participatory community programs for senior citizens.

초기 치매노인의 경험과 사회복지 개입방안에 대한 연구 - 주간보호센터를 이용하는 여성노인을 중심으로 -

최희경(Choi, Heekyung) 연세대학교 사회복지연구소 2017 한국사회복지조사연구 Vol.54 No.-

본 연구에서는 질적 연구방법을 통해 주간보호센터를 이용하는 여성 초기 치매노인 6명의 경험을 탐색하였다. 개인의 특성과 환경적 맥락의 상호작용을 중요시하는 심리사회적 접근방식을 기반 으로 초기 치매노인에게 적절한 조사방법을 활용하여 심층면접을 수행하였다. 그 결과 ‘기억의 편집’, ‘현재 나의 삶’, ‘나에게 일어난 변화’, ‘주변사람들’ 등 4가지 범주에서 12개의 주제묶음이 도출되었다. 주제묶음들은 치매와 관련하여 일상생활 및 자신에게 초래된 변화나 문제의 악화와 관련된 부정적 요소들(고착-평생에 한이 된 기억들, 상실과 좌절, 의존과 무력감, 고립과 단절 및관계의 악화, 부정과 의구심, 상대하기 싫은 사람들)과 더불어 변화에 대한 대처와 적응(회귀-내가 주인공이었던 시절, 수용과 유지, 독립과 대처, 규칙적 일과와 배우는 기쁨, 숨겨진 성격과 마음속 말들의 표출, 좋은 사람들과 지내기)이라는 두 가지 차원에서 파악되었다. 연구를 통해 초기 치매노 인의 경험의 다양성과 소통의 욕구를 확인하였으며, 초기 치매노인에 대한 사회복지 개입에 있어 개인의 생애에 나타난 기억의 고착이나 회귀의 의미 파악, 적응과 대처방식에 기반한 개입, 치매 진단의 공개 여부에 대한 고려, 초기 치매인에 특화된 주간보호프로그램의 필요성, 초기치매에 대한 효과적 대응과 부정적 고정관념의 극복 필요성을 제시하였다. The study aims to explore the experiences of elderly women with early-stage dementia using daycare center services on daily bases. Qualitative research was conducted by adopting research methods appropriate to persons with dementia based on the psycho-social approach to dementia which focused on interactions between persons and social environments. 4 categories(‘edition of memories’, ‘present life’, ‘changes of my life’, and ‘surrounding people’) and 12 themes were derived from the data of in-depth interviews with the 6 participants. The meanings of the experiences were analyzed by divided two dimensions, aggravating elements(fixed memories, loss and frustration, dependence and impotence, isolation and bad relationships, denial and suspicion, unpleasant people) and improving elements(regressed memories, acceptance and maintenance, independence and coping, routines and joy of learning, expression of hidden feelings, favorite people) of the challenges from dementia. The participants expressed needs for communication with people and diverse experiences related early-stage dementia. Several suggestions were made from the results of the study: paying attention to the repeated memories of the whole lives, implementing interventions based on individual adaptation and coping strategies, considering disclosure of dementia diagnosis, developing day care programs specialized for people with early-stage dementia, and overcoming negative stereotypes of dementia.