Motion Templates based User Interface for Immersive Virtual Reality Environment

Hasup Lee,Yoshisuke Tateyama,Tetsuro Ogi 보안공학연구지원센터 2012 International Journal of Control and Automation Vol.5 No.4

Background Subtraction Using Background Sets With Image- and Color-Space Reduction

Lee, Hasup,Kim, HyungSeok,Kim, Jee-In IEEE 2016 IEEE transactions on multimedia Vol.18 No.10

<P>Background subtraction is a basic step for a variety of multimedia applications such as live video, traffic monitoring, communication system, interactive learning space, etc. Many approaches have been proposed for this problem, but the need for lower cost approaches still exists. In this paper, a relatively low-cost background-subtraction method is proposed, using background sets with image- and color-space reduction. The background sets are used to detect objects from dynamic backgrounds, which contain waves, trees, and fountains. The image space is reduced to deal with jittered and unsteady frames, e.g., the input from handheld mobile devices. The color space is reduced to compensate for color noise, e.g., the scattered RGB values of a digital camera. To reduce the cost, a combination of color-space reduction and hash-table look-up operations are used. The results compared with other methods show the feasibility of our method; moreover, it can be useful in mobile or embedded environments.</P>

GalaxyGemini: a web server for protein homo-oligomer structure prediction based on similarity

Lee, Hasup,Park, Hahnbeom,Ko, Junsu,Seok, Chaok Oxford University Press 2013 Bioinformatics Vol.29 No.8

<P><B>Summary:</B> A large number of proteins function as homo-oligomers; therefore, predicting homo-oligomeric structure of proteins is of primary importance for understanding protein function at the molecular level. Here, we introduce a web server for prediction of protein homo-oligomer structure. The server takes a protein monomer structure as input and predicts its homo-oligomer structure from oligomer templates selected based on sequence and tertiary/quaternary structure similarity. Using protein model structures as input, the server shows clear improvement over the best methods of CASP9 in predicting oligomeric structures from amino acid sequences.</P><P><B>Availability:</B> http://galaxy.seoklab.org/gemini.</P><P><B>Contact:</B> chaok@snu.ac.kr</P><P><B>Supplementary information:</B> Supplementary data are available at <I>Bioinformatics</I> online.</P>

다중 디바이스를 이용한 유비쿼터스 가상현실

이하섭(Hasup Lee),김형석(Hyungseok Kim),이주영(Jooyoung Lee),고박우(Boyu Gao),김지인(Jee-In Kim) 한국HCI학회 2016 한국HCI학회 학술대회 Vol.2016 No.1

웨이브릿 기반의 3차원 물체 LOD 표현

이하섭(Hasup Lee),양현승(Hyun S. Yang) 한국정보과학회 2002 정보과학회논문지 : 시스템 및 이론 Vol.29 No.3·4

본 연구에서는, 거리 영상에서 mesh를 만들고 그것에서 다양한 LOD(Level of Detail)의 mesh를 생성하는 3차원 물체 LOD 모델링 시스템을 제안하였다. Initial mesh 생성은 마칭 큐브 알고리즘을 사용하였다. 종래의 알고리즘을 다수의 거리 영상에서 효과적으로 mesh를 생성하도록 개선하였다. Base mesh 생성에는 topology를 유지하면서 mesh를 간략화하는 decimation 알고리즘을 사용하였다. 마지막으로 Initial mash와 유사한 새로운 mesh를 생성할 때는 웨이블릿 변환을 적용하여 웨이블릿 개수를 개산하였다. 본 연구에서는 Base mesh를 생성할 때 mesh 간략화 방법을 사용함으로써 웨이블릿 기반의 치명적인 문제인 surface crease 문제를 해결하였다. In this paper, we propose a 3D object LOD(Level of Detail) modeling system that constructs a mesh from range images and generates the mesh of various LOD using the wavelet transform. In the initial mesh generation, we use the marching cube algorithm. We modify the original algorithm to apply it to construct the mesh from multiple range images efficiently. To get the base mesh we use the decimation algorithm which simplifies a mesh with preserving the topology. Finally, when reconstructing new mesh which is similar to initial mesh we calculate the wavelet coefficients by using the wavelet transform. We solve the critical problem of wavelet-based methods - the surface crease problem [1] - by using the mesh simplification as the base mesh generation method.

MIMO 환경 기반 멀티미디어 서비스 플랫폼 설계

이주영(Jooyoung Lee),김형석(HyungSeok Kim),고박우(Boyu Gao),이하섭(Hasup Lee),김지인(Jee-In Kim),임민규(Mingyu Lim) 한국HCI학회 2016 한국HCI학회 학술대회 Vol.2016 No.1

본 논문에서는 다중 디바이스 환경을 기반으로 한 멀티미디어 서비스 플랫폼 설계에 대하여 소개한다. 서비스에 참여하는 다수개의 디바이스의 구성을 능동적으로 파악하고, 디바이스 프로파일 및 사용자 프로파일을 이용하여 최적화된 콘텐츠의 출력 형태를 판별하는 프로세스에 대하여 설명한다. 서비스 콘텐츠의 형태와 서비스 제어 방법을 적응적으로 변환하는 모델을 마련하기 위하여, 사용자 프로파일 및 디바이스 프로파일 정량화를 수행하고, 사용성 측정을 위한 벤치마킹 테스트 방법을 소개한다. 이를 바탕으로 서로 다른 성능을 가지는 다수개의 디바이스 간의 실시간 출력 정보 동기화 뿐만 아니라 최종 출력 형태의 동기화가 이루어 질 수 있도록 하였다. 네트워크를 통하여 통합된 각 디바이스들은 서로간의 실시간 정보의 공유 및 교환을 통하여 현재 사용자 콘택스트에 적합한 형태의 정보를 제공하는 시스템 플랫폼 디자인에 대하여 설명 한다. In this paper, we introduce multimedia contents service platform based on multi-device environment. In this study, on user’s view point, service system automatically recognizes device configuration and determines optimal rendering form in current configuration based on profiling method. We introduce adaptive processing of contents considering user’s profile and device’s profile to make it have optimized rendering result and controlling method. Based on the process, it can achieve synchronized performance not only in information aspect but also in output form. By exchanging and sharing information between devices, our platform support to have an output result which is suitable for current user’s context.

Structure of vaccinia virus A46, an inhibitor of TLR4 signaling pathway, shows the conformation of VIPER motif : Structure of Vaccinia Virus A46

Kim, Yongwoon,Lee, Hasup,Heo, Lim,Seok, Chaok,Choe, Jungwoo Wiley-Blackwell Publishing, Inc. 2014 Protein science Vol. No.

<P>Vaccinia virus (VACV) encodes many proteins that interfere with the host immune system. Vaccinia virus A46 protein specifically targets the BB-loop motif of TIR-domain-containing proteins to disrupt receptor:adaptor (e.g., TLR4:MAL and TLR4:TRAM) interactions of the toll-like receptor signaling. The crystal structure of A46 (75-227) determined at 2.58 ? resolution showed that A46 formed a homodimer and adopted a Bcl-2-like fold similar to other VACV proteins such as A52, B14, and K7. Our structure also revealed that VIPER (viral inhibitory peptide of TLR4) motif resides in the α1-helix and six residues of the VIPER region were exposed to surface for binding to target proteins. In vitro binding assays between wild type and six mutants A46 (75-227) and full-length MAL identified critical residues in the VIPER motif. Computational modeling of the A46:MAL complex structure showed that the VIPER region of A46 and AB loop of MAL protein formed a major binding interface. In summary, A46 is a homodimer with a Bcl-2-like fold and VIPER motif is believed to be involved in the interaction with MAL protein based on our binding assays.</P>

GalaxyTongDock: Symmetric and asymmetric <i>ab initio</i> protein–protein docking web server with improved energy parameters

Park, Taeyong,Baek, Minkyung,Lee, Hasup,Seok, Chaok John Wiley Sons, Inc. 2019 Journal of computational chemistry Vol.40 No.27

<P>Protein–protein docking methods are spotlighted for their roles in providing insights into protein–protein interactions in the absence of full structural information by experiment. GalaxyTongDock is an <I>ab initio</I> protein–protein docking web server that performs rigid‐body docking just like ZDOCK but with improved energy parameters. The energy parameters were trained by iterative docking and parameter search so that more native‐like structures are selected as top rankers. GalaxyTongDock performs asymmetric docking of two different proteins (GalaxyTongDock_A) and symmetric docking of homo‐oligomeric proteins with C<SUB>n</SUB> and D<SUB>n</SUB> symmetries (GalaxyTongDock_C and GalaxyTongDock_D). Performance tests on an unbound docking benchmark set for asymmetric docking and a model docking benchmark set for symmetric docking showed that GalaxyTongDock is better or comparable to other state‐of‐the‐art methods. Experimental and/or evolutionary information on binding interfaces can be easily incorporated by using block and interface options. GalaxyTongDock web server is freely available at <url href='http://galaxy.seoklab.org/tongdock'>http://galaxy.seoklab.org/tongdock</url>. © 2019 Wiley Periodicals, Inc.</P>

Effects of Continuous Auditory Feedback on Drawing Trajectory-Based Finger Gestures

Gao, BoYu,Kim, HyungSeok,Lee, Hasup,Lee, Jooyoung,Kim, Jee-In IEEE 2018 IEEE transactions on human-machine systems Vol.48 No.6

<P>The well-known “fat finger” issue limits the interaction performance of trajectory-based finger gestures. To alleviate this issue, this work focuses on the possibility of using additional continuous auditory feedback to assist trajectory-based finger gestures. First, the experiment validated that, with the visual feedback only, the bare fingertip led to more errors in drawing of intersectional points, endpoints of closed gestures, and gestural length and shape variability compared to when the finger-attached pen was used. Then, we designed different types of auditory feedback (discrete beep, static, gradual) to provide additional information on the spatial relationship between finger-contact point and the endpoints or intersections of predefined gestures. An experiment that evaluates the effects of individual or combination of designed auditory feedback on trajectory-based finger gestures was conducted. These results show a few differences between them. However, a combination of gradual (amplitude and frequency) continuous sound and beep reached the highest drawing accuracy for trajectory-based finger gestures, which is similar to that of a finger-attached pen. This research offers insights and implications for the future design of continuous auditory feedback on small touchscreens.</P>

Prediction of Protein Structure and Interaction by GALAXY Protein Modeling Programs

Woong-Hee Shin,Gyu Rie Lee,Lim Heo,Hasup Lee,Chaok Seok 한국구조생물학회 2014 Biodesign Vol.2 No.1

In this review, recently developed GALAXY protein modeling programs are introduced and advantages and disadvantages of these programs for both program users and method developers are discussed. The GALAXY package consists of the template-based modeling program GalaxyTBM, the loop/terminus modeling program GalaxyLoop, the model refinement program GalaxyRefine, the homo-oligomer prediction program GalaxyGemini, and the protein-ligand docking program GalaxyDock. These programs have been tested with some success in community-wide competition Critical Assessment of Techniques for Protein Structure Prediction (CASP) experiments. For the development of these programs, modeling problems have been posed as global optimization problems of designed energy functions. The free energy functions of GALAXY have been carefully designed by combining physical chemistry principles and structure and sequence information. Efficient conformational search methods such as conformational space annealing and triaxial loop closure have been employed. Freely accessible web servers of the modeling programs are available at http://galaxy.seoklab.org, and some programs can be downloaded from http://galaxy.seoklab.org/softwares.