http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Biomechanical Properties of the Cranial Dura Mater with Puncture Defects : An In Vitro Study
Aydin, Hasan Emre,Kizmazoglu, Ceren,Kaya, Ismail,Husemoglu, Bugra,Sozer, Gulden,Havitcioglu, Hasan,Arslantas, Ali The Korean Neurosurgical Society 2019 Journal of Korean neurosurgical society Vol.62 No.4
Objective : The primary aim of this investigation was to explore the nature of dura mater biomechanics following the introduction of puncture defect(s). Methods : Twenty-eight dura mater specimens were collected during autopsy from the department of forensic medicine of the authors' institution. Specimens were divided randomly into one of four groups : group I (cranial dura mater; n=7), group II (cranial dura mater with one puncture defect; n=7); group III (cranial dura mater with two puncture defects; n=7), and group IV (cranial dura mater with three puncture defects; n=7). Results : The mean${\pm}$standard deviation tensile strengths of the dura mater were $8.35{\pm}3.16$, $8.22{\pm}3.32$, $7.13{\pm}1.77$, and $6.94{\pm}1.93MPa$ for groups I, II, III, and IV, respectively. There was no statistical difference between all groups. A single, two or more punctures of the dura mater using a 20-gauge Quincke needle did not affect cranial dura tensile strength. Conclusion : This biomechanical study may contribute to the future development of artificial dura mater substitutes and medical needles that have a lower negative impact on the biomechanical properties of dura mater.
A deep learning approach to permanent tooth germ detection on pediatric panoramic radiographs
Kaya, Emine,Gunec, Huseyin Gurkan,Aydin, Kader Cesur,Urkmez, Elif Seyda,Duranay, Recep,Ates, Hasan Fehmi Korean Academy of Oral and Maxillofacial Radiology 2022 Imaging Science in Dentistry Vol.52 No.-
Purpose: The aim of this study was to assess the performance of a deep learning system for permanent tooth germ detection on pediatric panoramic radiographs. Materials and Methods: In total, 4518 anonymized panoramic radiographs of children between 5 and 13 years of age were collected. YOLOv4, a convolutional neural network (CNN)-based object detection model, was used to automatically detect permanent tooth germs. Panoramic images of children processed in LabelImg were trained and tested in the YOLOv4 algorithm. True-positive, false-positive, and false-negative rates were calculated. A confusion matrix was used to evaluate the performance of the model. Results: The YOLOv4 model, which detected permanent tooth germs on pediatric panoramic radiographs, provided an average precision value of 94.16% and an F1 value of 0.90, indicating a high level of significance. The average YOLOv4 inference time was 90 ms. Conclusion: The detection of permanent tooth germs on pediatric panoramic X-rays using a deep learning-based approach may facilitate the early diagnosis of tooth deficiency or supernumerary teeth and help dental practitioners find more accurate treatment options while saving time and effort
A deep learning approach to permanent tooth germ detection on pediatric panoramic radiographs
Kaya Emine,Gunec Huseyin Gurkan,Aydin Kader Cesur,Urkmez Elif Seyda,Duranay Recep,Ates Hasan Fehmi 대한영상치의학회 2022 Imaging Science in Dentistry Vol.52 No.3
Purpose: The aim of this study was to assess the performance of a deep learning system for permanent tooth germ detection on pediatric panoramic radiographs. Materials and Methods: In total, 4518 anonymized panoramic radiographs of children between 5 and 13 years of age were collected. YOLOv4, a convolutional neural network (CNN)-based object detection model, was used to automatically detect permanent tooth germs. Panoramic images of children processed in LabelImg were trained and tested in the YOLOv4 algorithm. True-positive, false-positive, and false-negative rates were calculated. A confusion matrix was used to evaluate the performance of the model. Results: The YOLOv4 model, which detected permanent tooth germs on pediatric panoramic radiographs, provided an average precision value of 94.16% and an F1 value of 0.90, indicating a high level of significance. The average YOLOv4 inference time was 90 ms. Conclusion: The detection of permanent tooth germs on pediatric panoramic X-rays using a deep learning-based approach may facilitate the early diagnosis of tooth deficiency or supernumerary teeth and help dental practitioners find more accurate treatment options while saving time and effort.
Does Sunlight Exposure Improve Survival in Patients with Non-small Cell Lung Cancer?
Mutlu, Hasan,Buyukcelik, Abdullah,Aksahin, Arzu,Kibar, Mustafa,Cihan, Yasemin Benderli,Kaya, Eser,Seyrek, Ertugrul,Yavuz, Sinan,Erden, Abdulsamet,Calikusu, Zuleyha,Aslan, Tuncay,Akca, Zeki Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11
Background: Some epidemiological studies reported that sunlight exposure and highvitamin D levels may decrease the morbidity and mortality related to cancer. We aimed to evaluate whether sunlight exposure has an impact on survival in patients with non small cell lung cancer. Materials and Methods: A total of 546 patients with NSCLC from two different regions (Kayseri and Adana) differing according to sunlight exposure were analysed retrospectively. Results: The median overall survival (OS) rates were 11. 6 (CI: 9.50-13.6) and 15.6 months (CI: 12.4-18.8) for Kayseri and Adana, respectively, in all patients (p=0.880). Conclusions: There were no differences between groups in terms of OS. While there is strong evidence regarding inverse relationship between cancer incidence and sunlight exposure, it is still controversial whether sunlight exposure is a good prognostic factor for survival in patients with lung cancer.
Mutlu, Hasan,Buyukcelik, Abdullah,Erden, Abdulsamet,Aslan, Tuncay,Akca, Zeki,Kaya, Eser,Kibar, Mustafa,Seyrek, Ertugrul,Yavuz, Sinan,Calikusu, Zuleyha Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
Background: Of patients with non small cell lung cancer (NSCLC), around one third are locally advanced at the time of diagnosis. Because only a proprotion of stage III patients can be cured by surgery, in order to improve the outcomes, sequential or concurrent chemoradiation, or concurrent chemoradiation with induction or consolidation is offered to the patients with locally advanced NSCLC. Today, PET combined with computerized tomography (PET-CT) is accepted as the most sensitive technique for detecting mediastinal lymph node and extracranial metastases from NSCLC. We aimed to compare PET-CT and conventional staging procedures for decisions regarding curative treatment of locally advanced NSCLC. Materials and Methods: A total of 168 consecutive patients were included from Acibadem Kayseri Hospital, Acibadem Adana Hospital and Kayseri Research and Training Hospital in this study. Results: While the median PFS was $13.0{\pm}1.9$ months in the PET-CT group, it was only $6.0{\pm}0.9$ in the others (p<0.001). The median OS values were $20.5{\pm}15.6$ and $11.5{\pm}1.5$ months, respectively (p<0.001). Discussion: As a result, we found that staging with PET CT has better results in terms of survival staging. This superiority leads to survival advantage in patients with locally advanced NSCLC.
Berna Cagatay Kaya,Hasan Karadag,Ozgur Oner,Aysegul Kart,Mehmet Hakan Turkcapar 대한신경정신의학회 2015 PSYCHIATRY INVESTIGATION Vol.12 No.2
ObjectiveaaAltered serum S100B protein levels have been shown in several psychiatric disorders. Our aim was to investigate whether plasma S100B is different in patients with panic disorder (PD) when compared with controls. Our second aim was to investigate whether treatment with SSRIs have an effect on S100B levels in patients with PD. MethodsaaThe sample included 32 patients diagnosed with PD (21 women, 11 men) per DSM-IV criteria and 21 healthy controls (11 women, 10 men). S100B levels were measured with BioVendor Human S100B ELISA (Enzyme Linked Immunosorbent Assay) kit. Resultsaa14 patients were not on drug treatment (43.8%) while 18 patients were taking various SSRIs. Median S100B value was 151.7 pg/mL (minimum-maximum: 120.4–164.7 pg/mL) in the control group, 147.4 pg/mL (minimum-maximum: 138.8–154.1 pg/mL) in the drug free group and 153.0 pg/mL (minimum-maximum: 137.9–164.7 pg/mL) in the treatment group. Kruskal-Wallis analysis showed a significant diffrerence among the three groups (z=9.9, df=2, p=0.007). Follow up Mann-Whitney-U tests indicated that while the control and the patients with treatment were not significantly different (z=-0.05, p=0.96), there were significant differences between the control group and untreated patients (z=-2.6, p=0.009) and treated and untreated patients (z=-3.0, p=0.003). ConclusionaaOur results suggested that, serum S100B protein level might be decreased in untreated PD patients and that patients who were treated with SSRIs had similar S100B level to healthy controls.
Novel SPD Method: Twisted Variable Channel Angular Extrusion
Kerim Özbeyaz,Hasan Kaya,Aykut Kentli 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.5
Different types of SPD techniques are applicable and have been studied by various researchers. All of them have severaladvantages and disadvantages. Equal Channel Angular Pressing (ECAP) is one of the most popular SPD techniques and isstill being developed. The aim of this paper is to improve the efficiency of ECAP process by putting forward a novel design(Twisted Variable Channel Angular Pressing (TV-CAP)) and also to achieve higher mechanical properties when comparedto conventional ECAP processes. For this purpose, a new TV-CAP die was designed by combining three different methods:ECAP, Twist Extrusion, and Direct Extrusion. The new design was able to integrate the advantages of each methodto the workpiece material. In this context, the design parameters of the TV-CAP die were first identified by finite elementanalysis (FEA) in Deform-3D. The TV-CAP die was produced according to the determined parameters and AA5083 alloywas pressed with this novel die. Hardness and tensile tests were carried out to compare mechanical properties. In addition,Optical Microscope, SEM, TEM images were taken, and XRD and EBSD analyses were carried out to examine the changesin grain structure. As a result of this experimental study, an increase of 197.3% was observed in the hardness value and anincrease of 144.7% was achieved in the tensile strength value by using the novel TV-CAP die. These results also agreed withthe effective strain values obtained from the FEA.
Filiz Kılıç,Murat Coşkun,Hasan Bozkurt,Ilyas Kaya,Salih Zoroǧlu 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.2
Objective: To explore the role of trauma and dissociation over self-injurious behaviors (SIB) and suicide attempts (SA) in adolescents. Methods: A total of 207 adolescents participated in the study. After conducting diagnostic interview, participants were divided into five groups as subjects with dissociative disorders (DD), attention deficit hyperactivity disorder (ADHD), major depressive disorder (MDD) and anxiety disorders (AD), and a control group (CG) without any psychiatric disorder. ADHD, MDD and AD groups were considered as non-dissociative disorders (non-DD group) in the present study. Results: There is no significant difference between groups in terms of number and age of the subjects (p>0.05). Among all participants SIB was reported in 32.2% of females (n=37) and 25% of males (n=23) while SA was reported in 29.6% of females (n=34) and 4.4% of males (n=4). Adolescents with DD were found to experience higher rates of SIB and SA than the other groups. Dissociation was the most important variable contributing to SIB and female gender was the most efficient variable for SA. Total trauma scores were also found to be significantly higher in DD group followed by non-DD and CG respectively. Conclusion: SIB and SA are complex behavioral problems which may be associated with many psychiatric factors. However higher level dissociation seems as an important mediating factor, even regardless of psychiatric diagnosis, in the development of SIB and SA. More research is needed to further explore the factors effective over SIB and SA in adolescents.