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Weight Optimization of the Gearbox Using Interior Point Method
Mehmet Enes Avcu,Harun Gökçe 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.1
Weight is important subject to industry that produce machine like truck, grader etc. Thus, weight optimization problem is challenging area to work at optimization area. A few optimization solution is already exit in literature. However, these algorithms are meta-heuristic algorithms. In this study, numerical optimization algorithm implemented for weight optimization problem. The interior point method (IPM) is most powerful algorithm for nonlinear programming (Nocedal and Wright in Numerical optimization, Springer, Berlin, 2006). We show the result of IPM algorithm and check against meta-heuristic algorithms.
The protective effect of Myrtus communis L. against experimental kidney stone in rats
Halil Yılmaz,Nihat Ekinci,Ayşe Ömerli,Mehtap Nisari,Arzu Hanım Yay,Harun Ülger,Karatoprak Gökçe Şeker,Seher Yımaz,Şükrü Ateş,Mustafa aştan 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.1
The aim of this study is to investigate the protective effect of 70% methanolic extract of Myrtus communis L. leaves (300 mg/kg) against the kidney stone modeling created by (0.75%) ethylene glycole. Twenty-eight, 10 week’s Sprague Dawley male rats were divided into four groups (n = 7) as the control group, ethylene glycol (EG) group, M. communis (MC) group and protective (EG + MC) group. For 28 days, while 0.75% EG was given by adding it to drinking water to occur kidney stone model, MC was given by gavage to test the protective effect. 24 h’ urine samples were taken, and calcium, creatinine, uric acid, magnesium, citrate and oxalate were evaluated. On the 28th day, the rats were sacrificed, and their kidneys were removed. Kidney tissues were examined with hematoxylin eosin (HE) staining and kidney stones formed with Pizzolato’s (PZ) staining technique were shown. M. communis extract brought abnormal urine parameter values closer to the control group. Additionally, it was concluded that the tissue degeneration and number of stones decreased in the protective group. M. communis extract has a protective effect against the kidney stone modeling which created by EG.