Analysis of thermally induced vibration of cable-beam structures

Han-Qing Deng,Tuan-Jie Li,Bi-Jie Xue,Zuo-Wei Wang 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.53 No.3

Cable-beam structures characterized by variable stiffness nonlinearities are widely found in various structural engineering applications, for example in space deployable structures. Space deployablestructures in orbit experience both high temperature caused by sun’s radiation and low temperature by Earth’s umbral shadow. The space temperature difference is above 300K at the moment of exiting or entering Earth’s umbral shadow, which results in structural thermally induced vibration. To understand the thermally induced oscillations, the analytical expression of Boley parameter of cable-beam structures is firstly deduced. Then, the thermally induced vibration of cable-beam structures is analyzed using finite element method to verify the effectiveness of Boley parameter. Finally, by analyzing the obtained numerical results and the corresponding Boley parameters, it can be concluded that the derived expression of Boley parameter is valid to evaluate the occurrence conditions of thermally induced vibration of cable-beam structures and the key parameters influencing structural thermal flutter are the cable stiffness and thickness of beams.

Analysis of thermally induced vibration of cable-beam structures

Deng, Han-Qing,Li, Tuan-Jie,Xue, Bi-Jie,Wang, Zuo-Wei Techno-Press 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.53 No.3

Cable-beam structures characterized by variable stiffness nonlinearities are widely found in various structural engineering applications, for example in space deployable structures. Space deployable structures in orbit experience both high temperature caused by sun's radiation and low temperature by Earth's umbral shadow. The space temperature difference is above 300K at the moment of exiting or entering Earth's umbral shadow, which results in structural thermally induced vibration. To understand the thermally induced oscillations, the analytical expression of Boley parameter of cable-beam structures is firstly deduced. Then, the thermally induced vibration of cable-beam structures is analyzed using finite element method to verify the effectiveness of Boley parameter. Finally, by analyzing the obtained numerical results and the corresponding Boley parameters, it can be concluded that the derived expression of Boley parameter is valid to evaluate the occurrence conditions of thermally induced vibration of cable-beam structures and the key parameters influencing structural thermal flutter are the cable stiffness and thickness of beams.

Strong and biocompatible poly(lactic acid) membrane enhanced by Ti₃C₂T_z (MXene) nanosheets for Guided bone regeneration

Chen, Ke,Chen, Youhu,Deng, Qihuang,Jeong, Seol-Ha,Jang, Tae-Sik,Du, Shiyu,Kim, Hyoun-Ee,Huang, Qing,Han, Cheol-Min Elsevier 2018 Materials letters Vol.229 No.-

<P><B>Abstract</B></P> <P>Herein, strong and biocompatible Ti<SUB>3</SUB>C<SUB>2</SUB>T<SUB>z</SUB>-enhanced poly(lactic acid) (PLA) nanocomposite membranes were prepared. The interface of the Ti<SUB>3</SUB>C<SUB>2</SUB>T<SUB>z</SUB> nanosheets with the hydrophobic PLA matrix was mediated using n-octyltriethoxysilane (OTES). The optimized ultimate tensile strength of the OTES-Ti<SUB>3</SUB>C<SUB>2</SUB>T<SUB>z</SUB>/PLA nanocomposite membrane was 72 MPa (33% higher than that of a pure PLA membrane). The addition of Ti<SUB>3</SUB>C<SUB>2</SUB>T<SUB>z</SUB> enhanced the biological properties of the membrane, including the <I>in vitro</I> adhesion, proliferation, and osteogenic differentiation of MC3T3-E1 mouse preosteoblasts.</P> <P><B>Highlights</B></P> <P> <UL> <LI> First effort to introduce MXene into polymer matrix for tissue engineering. </LI> <LI> A robust strategy developed to prepare Ti<SUB>3</SUB>C<SUB>2</SUB>T<SUB>z</SUB>-enhanced PLA nanocomposite. </LI> <LI> Successful interfacial mediation between hydrophilic Ti<SUB>3</SUB>C<SUB>2</SUB>T<SUB>z</SUB> nanosheets and hydrophobic PLA. </LI> <LI> Intriguing future of this strong and biocompatible nanocomposite for GBR membrane. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Study on mechanical behaviors of loose mortise-tenon joint with neighbouring gap

Jun-xiao He,Juan Wang,Qing-shan Yang,Miao Han,Yang Deng 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.77 No.4

The neighbouring gaps at the mortise-tenon joint in traditional timber structure, which leads to the complexity of the joint, are considered to impair the mechanical performance of the joint. In this paper, numerical simulation of loose joint was conducted to examine the deformation states, stress distributions, and bearing capacities, which was verified by full-scale test. On the basis of the experimental and numerical results, a simplified mechanics model with gaps has been proposed to present the bending capacity of the loose joint. Besides, the gap effects and parameter studies on the influences of tenon height, friction coefficient, elastic modulus and axial load were also investigated. As a result, the estimated relationship between moment and rotation angle of loose joint showed the agreement with the numerical results, demonstrating validity of the proposed model; The bending bearing capacity and rotational stiffness of loose joint had a certain drop with the increasing of gaps; and the tenon height may be the most important factor affecting the mechanical behaviors of the joint when it is subjected to repeated load; Research results can provide important references on the condition assessments of the existing mortise-tenon joint.

The ways for ginsenoside Rh2 to fight against cancer: the molecular evidences in vitro and in vivo.

Qi-rui Hu,Yao Pan,Han-cheng Wu,Zhen-zhen Dai,Qing-xin Huang,Ting Luo,Jing Li,Ze-yuan Deng,Fang Chen The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.2

Cancer is a global public health issue that becomes the second primary cause of death globally. Considering the side effects of radio- or chemo-therapy, natural phytochemicals are promising alternatives for therapeutic interventions to alleviate the side effects and complications. Ginsenoside Rh2 (GRh2) is the main phytochemical extracted from Panax ginseng C.A. Meyer with anticancer activity. GRh2 could induce apoptosis and autophagy of cancer cells and inhibit proliferation, metastasis, invasion, and angiogenesis in vitro and in vivo. In addition, GRh2 could be used as an adjuvant to chemotherapeutics to enhance the anticancer effect and reverse the adverse effects. Here we summarized the understanding of the molecular mechanisms underlying the anticancer effects of GRh2 and proposed future directions to promote the development and application of GRh2.

Thalidomide Combined with Chemotherapy in Treating Patients with Advanced Colorectal Cancer

Huang, Xin-En,Yan, Xiao-Chun,Wang, Lin,Ji, Zhu-Qing,Li, Li,Liu, Meng-Yan,Qian, Ting,Shen, Hui-Ling,Gu, Han-Gang,Liu, Yong,Gu, Ming,Deng, Li-Chun Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17

Objective: To assess the safety and effectiveness of thalidomide (produced by CHANGZHOU PHARMACEUTICAL FACTORY CO.LTD) combined with chemotherapy in treating patients with advanced colorectal cancer. Method: A consecutive cohort of pretreated patients with advanced colorectal cancer were treated with thalidomide combined with chemotherapy. And chemotherapy for patients with advanced colorectal cancer were administered according to the condition of patients. Thalidomide was orally administered at a dosage of 50mg/day to 150mg/day before sleeping for at least 14 days. After at least 14 days of treatment, safety and side effects were evaluated. Results: There were 12 female and 3 male patients with advanced cancer recruited into this study, including 9 patients with colon, 6 patients with rectal cancer. The median age of patients was 57(41-82) years. Partial response was observed in 2 patients (2/15), and stable disease in 3 patients(3/15). Incidences of Grade 1 to 2 myelosuppression was observed in 1/15 patients, and Grade 1 to 2 elevation of hepatic enzyme was recorded in 1/15 patients. Adverse effects on the gastrointestinal tract were documented in 1/15 patients, and were Grade 1. No Grade 3-4 toxicities were diagnosed. No treatment related death was found. Conclusions: Thalidomide combined with chemotherapy was safe and mildly effective in treating patients with advanced colorectal cancer. However, further study should be conducted to clarify the effectiveness of this combination.