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Determination of Cu site in L10-FePtCu alloy using ALCHEMI method
Han Wool Ryu 한양대학교 세라믹연구소 2014 Journal of Ceramic Processing Research Vol.15 No.6
The Cu site in L10-ordered ternary FePtCu alloy was quantitatively determined using atom location by channeling enhanced microanalysis (ALCHEMI). The lattice parameter measured by XRD result was a = 0.388 ± 0.0003 nm and c = 0.369 ± 0.0009 nm with an axial ratio c/a of 0.951 ± 0.0003 for ternary L10-ordered FePtCu phase. The alloy composition of bulk ternary L10- ordered FePtCu phase was Fe40Pt50.4Cu9.6 measured by inductively coupled plasma atomic emission spectrometer (ICP-AES). The ALCHEMI result obtained from calculation of the characteristic X-ray spectra demonstrates Cu almost occupies the Fe site in ternary L10-ordered FePtCu alloy.
이한울(Lee, Han-Wool),유상모(Ryu, Sang-Mo),정의봉(Jeong, Weui-Bong),한형석(Han, Hyung-Suk),안재우(Ahn, Jae-Woo),정상우(Jeong, Sang-Woo) 한국소음진동공학회 2010 한국소음진동공학회 논문집 Vol.20 No.10
This paper deals with the process to identify the exciting forces generated from a rotary compressor. The equation of motion of a rigid compressor supported by several mounts was derived with 6 degree of freedom. The mass moment of inertia of compressor and the stiffness of rubber mounts were also identified by experiments. The exciting force at the center of mass of the compressor were estimated from the acceleration data measured at compressor shell. The piping system connected to the compressor was modeled. The acceleration of a pipe was predicted numerically by using the predicted exciting force. The numerical results showed good agreement with experimental results, which validated the identified exciting force.
Han, Won Ho,Yehuda, Amir Ben,Kim, Deok-Hee,Yang, Seung Geun,Eom, Bang Wool,Yoon, Hong Man,Kim, Young-Woo,Ryu, Keun Won AME Publishing Company 2018 Chinese Journal of Cancer Research Vol.30 No.5
<P><B>Objective</B></P><P>Laparoscopic gastrectomy has been established as a standard treatment for early gastric cancer, and its use is increasing recently. Compared with the conventional laparoscopy-assisted distal gastrectomy (LADG), totally laparoscopic distal gastrectomy (TLDG) involves intracorporeal reconstruction, which can avoid the additional incision, resulting in pain reduction and early recovery. This study aimed to compare the short-term postoperative outcomes of TLDG <I>vs.</I> LADG in gastric cancer in a high-volume center. </P><P><B>Methods</B></P><P>A retrospective cohort study was conducted on 1,322 patients who underwent laparoscopic distal gastrectomy from June 2012 to June 2017 at the National Cancer Center, Korea. LADG was performed in the early period before July 2015, and TLDG was applied in the later period. Postoperative short-term outcomes were compared in terms of complication and clinical course between the two groups. Pain score was measured by rating the pain intensity from 0 to 10 points on postoperative day (POD) 1 and 3.</P><P><B>Results</B></P><P>A total of 667 patients underwent LADG and 655 patients underwent TLDG. Clinicopathologic characteristics were not different in both groups. Intraoperative estimated blood loss (EBL) was significantly lower in the TLDG group (P<0.001). Postoperative pain scores were significantly lower in the TLDG group than in the LADG group on POD 1 (5.1±1.5<I>vs.</I> 4.8±1.4, P=0.015). First flatus passage after operation was significantly earlier in the TLDG group (3.4±0.8 d <I>vs.</I> 3.2±0.6 d, P<0.001). There were no differences in postoperative complications and hospital stay between the two groups. </P><P><B>Conclusions</B></P><P>Based on the reported short-term postoperative outcomes, TLDG is safe and feasible as well as LADG. Moreover, compared with LADG, TLDG can reduce intraoperative EBL and postoperative pain and enhance the bowel motility in gastric cancer surgery.</P>
Han, Mi Ah,Kim, Young-Woo,Choi, Il Ju,Oh, Myueng Guen,Kim, Chan Gyoo,Lee, Jong Yeul,Cho, Soo-Jeong,Eom, Bang Wool,Yoon, Hong Man,Ryu, Keun Won American Association for Cancer Research 2013 Cancer epidemiology, biomarkers & prevention Vol.22 No.10
<P><B>Background:</B> Smoking and drinking alcohol are major risk factors for cancer development, and we investigated their effects on gastric cancer prognosis following initial resection.</P><P><B>Methods:</B> Data from male patients with stage III–IV gastric adenocarcinoma who underwent surgery between 2001 and 2006 were retrospectively reviewed. Patients were followed up until 2011. Kaplan–Meier plots and Cox proportional hazards regressions were applied for survival rates.</P><P><B>Results:</B> Among 238 patients, 151 (63.4%) smoked and 146 (61.3%) drank alcohol. Current smokers had an increased risk of cancer recurrence or death from any cause [adjusted HR (aHR), 1.94; 95% confidence interval (CI), 1.18–3.21], cancer recurrence (aHR, 1.89; 95% CI, 1.12–3.21), and overall mortality (aHR, 2.14; 95% CI, 1.23–3.73) compared with never-smokers. Patients with a lifetime cigarette smoking of <40 and ≥40 pack-years had increased cancer recurrence or death from any cause (aHR, 1.72 and 2.43, respectively; 95% CI, 1.03–2.86 and 1.38–4.30, respectively), cancer recurrence (aHR, 1.63 and 2.61, respectively; 95% CI, 0.95–2.79 and 1.43–4.77, respectively), and overall mortality (aHR, 1.92 and 2.75, respectively; 95% CI, 1.09–3.38 and 1.47–5.12, respectively) compared with never-smokers. However, drinking alcohol was not associated with postsurgery survival.</P><P><B>Conclusions:</B> Cigarette-smoking history at the time of diagnosis, but not drinking history, is associated with cancer recurrence and poor survival after surgery in male patients with stage III–IV gastric cancer.</P><P><B>Impact:</B> These findings encourage physicians to advise patients with gastric cancer to stop smoking to obtain a general health benefit and likely improvement in the gastric cancer course. <I>Cancer Epidemiol Biomarkers Prev; 22(10); 1805–12. ©2013 AACR</I>.</P>
Han, Won Ho,Eom, Bang Wool,Yoon, Hong Man,Ryu, Junsun,Kim, Young-Woo The Korean Gastric Cancer Association 2020 Journal of gastric cancer Vol. No.
Purpose: Proximal gastrectomy (PG) is a function-preserving surgery in cases of proximally located early-stage gastric cancer. Because gastroesophageal reflux is a major pitfall of this operation, we devised a modified esophagogastrostomy (EG) anastomosis to fix the distal part of the posterior esophageal wall to the proximal part of the anterior stomach wall to produce an anti-reflux mechanism; we named this the SPADE operation. This study aimed to show demonstrate the clinical outcomes of the SPADE operation and compare them to those of previous PG cases. Materials and Methods: Case details of 56 patients who underwent PG between January 2012 and March 2018 were retrospectively reviewed: 30 underwent conventional esophagogastrostomy (CEG) anastomosis using a circular stapler, while 26 underwent the SPADE operation. Early postoperative clinical outcome-related reflux symptoms, endoscopic findings, and postoperative complications were compared in this case-control study. Results: Follow-up endoscopy showed more frequent reflux esophagitis cases in the CEG group than in the SPADE group (30% vs. 15.3%, P=0.19). Similarly, bile reflux (26.7% vs. 7.7%, P=0.08) and residual food (P=0.01) cases occurred more frequently in the CEG group than in the SPADE group. In the CEG group, 13 patients (43.3%) had mild reflux symptoms, while 3 patients (10%) had severe reflux symptoms. In the SPADE group, 3 patients (11.5%) had mild reflux symptoms, while 1 had severe reflux symptoms (absolute difference, 31.8%; 95% confidence interval, 1.11-29.64; P=0.01). Conclusions: A novel modified EG, the SPADE operation, has the potential to decrease gastroesophageal reflux following a PG.
Design and Implementation of a Real-time Radiosonde Location System for Upper-air Observations
Min-Woo Ryu,Sang-Shin Lee,Jaeseok Yun,Il-Yeup Ahn,Han-Wool Seok 한국산학기술학회 2014 SmartCR Vol.4 No.1
A radiosonde is a piece of equipment for analyzing changes in the atmosphere in three dimensions from the ground up to a maximum altitude of 3,500 meters. The radiosonde moves through the upper air at 5 m/s and collects upper-air data, such as atmospheric pressure, temperature, wind direction and wind speed. The upper-air data is used as basic research data for improving weather forecasts and handling climate change. However, handling climate change in real-time is difficult because the collected upper-air data from the radiosondes are transmitted to the World Meteorological Organization after completion of the flights. To resolve this problem, this paper proposes the design and implementation of a real-time radiosonde location and representation system to improve atmospheric analysis of upper-air observations.
Eom, Bang Wool,Kim, Young-Woo,Nam, Byung-Ho,Ryu, Keun Won,Jeong, Hyun-Yong,Park, Young-Kyu,Lee, Young-Joon,Yang, Han-Kwang,Yu, Wansik,Yook, Jeong-Hwan,Song, Geun Am,Youn, Sei-Jin,Kim, Heung Up,Noh, Su The Korean Gastric Cancer Association 2016 Journal of gastric cancer Vol.16 No.3
Purpose: This study aimed to establish a large-scale database of patients with gastric cancer to facilitate the development of a nationalcancer management system and a comprehensive cancer control policy. Materials and Methods: An observational prospective cohort study on gastric cancer was initiated in 2010. A total of 14 cancer centers throughout the country and 152 researchers were involved in this study. Patient enrollment began in January 2011, and data regarding clinicopathological characteristics, life style-related factors, quality of life, as well as diet diaries were collected. Results: In total, 4,963 patients were enrolled until December 2014, and approximately 5% of all Korean patients with gastric cancer annually were included. The mean age was $58.2{\pm}11.5$ years, and 68.2% were men. The number of patients in each stage was as follows: 3,394 patients (68.4%) were in stage IA/B; 514 patients (10.4%), in stage IIA/B; 469 patients (9.5%), in stage IIIA/B/C; and 127 patients (2.6%), in stage IV. Surgical treatment was performed in 3,958 patients (79.8%), endoscopic resection was performed in 700 patients (14.1%), and 167 patients (3.4%) received palliative chemotherapy. The response rate for the questionnaire on the quality of life was 95%; however, diet diaries were only collected for 27% of patients. Conclusions: To provide comprehensive information on gastric cancer for patients, physicians, and government officials, a large-scale database of Korean patients with gastric cancer was established. Based on the findings of this cohort study, an effective cancer management system and national cancer control policy could be developed.
단일 기관에서 경험한 소아청소년기 Kikuchi-Fujimoto병의 임상적 고찰
강희원,김한울,이소영,유경하,김혜순,유은선,최희정,김경효 이화여자대학교 의과학연구소 2018 EMJ (Ewha medical journal) Vol.41 No.4
Objectives: Kikuchi-Fujimoto disease (KFD) is characterized by lymphadenopathy and fever, and is usually self-limited. This study analyzed the clinical characteristics of pediatric patients with KFD. Methods: This retrospective, observational, single-center study was conducted in South Korea from March 2008 to October 2015. KFD was diagnosed based on clinical, radiological or histological findings and excluded when there were any other causes of lymphadenopathy. Medical records were reviewed for clinical and laboratory manifestations. Results: A total of 35 cases were included. The mean patient age was 12.1±2.9 years (range, 5 to 17 years); the male-to-female ratio was 1:0.8. The main clinical manifestations were cervical lymphadenopathy and fever in 34 cases (97%). The mean duration of fever was 12.2±8.3 days (range, 2 to 37 days). We noted enlargement of lymph nodes in the cervical, mesenteric (n=5, 14%), axillary (n=2, 6%), and inguinal (n=1, 3%) regions. Hepatosplenomegaly, loss of appetite, and rash were observed. On laboratory examinations, elevation of ferritin, leukopenia, and positivity for anti-nuclear antibodies were frequently observed. Twelve patients underwent biopsy and 23 cases were diagnosed by radiological findings. The mean duration of hospitalization for all cases was 7.9±2.9 days (range, 3 to 13 days) and steroids were administered in 10 cases. KFD recurrence was observed in 2 cases (5.7%) with the time to relapse of 7 months and 4 years. There were no cases with systemic lupus erythematous or other autoimmune disease. Conclusion: KFD should be considered in pediatric patients with lymphadenopathy and prolonged fever. Patients with KFD should be monitored for recurrence and the development of autoimmune disease.