http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
일부 병원에 내원한 암환자들의 대체의학 사용에 관한 연구
최윤정,정해원,최수용 대한보건협회 1998 대한보건연구 Vol.24 No.1
대체의학은 말 그대로 다른 것을 의미하며 효과와 안전성이 과학적으로 증명되지 않았거나 과학적으로 효과가 없다고 증명된 치료법으로 병원에서 널리 시술되지 않거나 정규 의학 교육과정에서 가르치지 않는 치료이다. 본 연구의 목적은 암환자를 대상으로 하여 대체의학 사용양상을 평가하고 대체의학 사용과 관련된 암환자 특성을 기술하는 데 있다. 조사대상자는 서울에 소재한 원사력병원에서 1997년 8월에서 그 해 10월 사이에 병원에 입원한 환자 중 암으로 최종 진단받은 308명을 대상으로 하였다. 본 연구결과는 다음과 같다. 1. 조사대상자 308명 중 63.0%(194명)이 대체의학을 사용한 경험이 있었다. 2. 대체요법 종류별 사용률은 식이 및 영양요법이 52.3%로 가장 높았으며, 그 다음이 약초요법(44.8%), 한방요법(12.7%), 신체 정신요법(10.4%) 그리고 약물요법(6.8%)의 순이었다. 3. 암이환 기간이 길수록 대체요법의 사용이 많았다.(P<0.01) 4. 치료상태가 무이거나 수술만 받은 경우에 비하여 방사선요법, 약물요법, 병행요법을 받은 경우 대체요법의 사용이 4.3(95% CI: 2.3∼8.3)배 높았다. 5. 경제수준이 '상'인 경우가 '중'이나 '하'인 경우에 비하여 대체의요법 사용이 3.3(95% CI: 1.02-8.9)배 높게 나타났다. 6. 대체요법으로 소요된 평균 비용은 187만원이었다. 7. 사용자의 대체의학에 대한 기대는 큰 편이었다(66.3%). 8. 대체요법을 사용하게 된 경로로는 43.5%가 이웃 및 다른 암환자, 22,1%는 미디어(신문·잡지), 20.9%는 가족이나 친척으로부터 이었다. 9. 대체요법의 부작용을 경험한 적이 있다고 한 암환자는 8.8%이였다. Alternative medicines include all of the approaches and techniques that until the past few years were not taught in medical school and residency training nor reported in the medical journals that most physicians ordinarily read. The aim of this study is to assess the patterns of alternative medicines and to describe the characteristics of cancer patients used alternative medicines. The subjects were 308 patients with cancer who had been diagnosed as cancers admitted at Korea Cancer Center Hospital from August to October in 1997. The results of this study were summarized as follows : 1. 194 patients(63.0%) among 308 cancer patients had used alternative medicines. 2. The rate of alternative therapy use was 52.3% for diet and nutritions, 44.8% for herbal medicines, 12.7% for oriental medicines, 10.4% for mind-body interventions and 6.8% for pharmacological and biologic treatments. 3. Alternative therapy users had longer morbidity periods than non-users.(P<0.01) 4. The odds ratio for cancer patients with conventional treatments such as radiotherapy, chemotherapy and combined therapies was 4.3(95% CI: 2.3-8.3) compared with patients with non-treatment and surgery. 5. The odds ratio for cancer patients with high class in economic status is 3.3(95% CI: 1.02-8.9) compared with patients with low and middle class. 6. The average cost of alternative therapies was 1.870 thousands won. 7. Expectation of the use of alternative therapies was relatively high. 8. Information sources for using alternative therapies received from neighbors or other cancer patients(43.5%), media(22.1%) and, family and their relatives(20.9%). 9. 8.8% of alternative therapy users had ever experienced side effect or adverse effect.
千基貞,柳炳善,鄭圭會,鄭海元,李鉦浩 대한방사선 방어학회 1985 방사선방어학회지 Vol.10 No.1
The objectives of present study is to investigate genetic damage of radiation in mammalian male germ cell and to establish available screening method for determining genetic hazard by radiation. Several methods were employed to measure the genetic damage of radiation as follows: Sperm head counts, frequency occurrence of sperm with abnormal head shape, fertility, activity of LDH-X, and the induction of unscheduled DNA synthesis (U.D.S.) in male mouse were performed with the passing of time after irradiation by making use of the sequence of event that occurs during spermatogenesis. Sperm head counts and activity of LDH-X in testes were gradually reduced by increased radiation dose and with the passing of the time after irradiation. Frequency occurrence of sperm with abnormal head shape, sterile period, and the induction of unscheduled DNA synthesis were increased by increased radiation dose. It is suggested that since germ cell is a direct reflection of genetic complement, the use of male germ cell is rapid and convenient method for measuring genetic damage by radiation.
Polymorphisms of GSTM1,GSTT1,GSTP1,NATII and CYP1A1 and the Susceptibility to Asthma
Chung, Hai Won,Ahn, Tai Hui,Kim, Su Young,Kim, Tae Yon,Paek, Domyung 한국유전학회 2002 Genes & Genomics Vol.24 No.3
The associations of asthma with genetic polymorphisms remains unclear. The purpose of this study is to find the association of NA72, GSTM1, GS7T1, GS7P1 and CYP1A1 polymorphism with asthma in Koreans. The genetic polymorphisms of GS7M1, GS7T1, GS7P1, NA7II and CYP1A1 genes among 33 asthma patients and 66 controls were investigated to find the association of the polymorphism with the risk of asthma. The frequency of the GS7Tl null genotype was slightly higher in asthma patients than that in controls, but this difference was not statistically significant. No difference in the frequencies of GS7T1 and GS7Pl was found between patients and controls. Excess risk for the combined GS7T1 and GS7M1 null genotype was found (O.R = 7.62, 95% CI: 1.13-51.46). There was no association with asthma risk by NA72 genotypes. The presence of the homozygous variant type (M/M of CYP1A1 led to the increased risk (O.R = 4.40, 95% CI:1.01-19.29) for asthma compared to wild type (WT) and heterozygous variant type (W/M). An increased risk of asthma for the combined GS7T1 null genotype (MM and CYP1A1 homozygous variant genotype (M/M) was also found (O.R. = 11.61, 95% CI: 1.14 - 118.43). The CYP1AI genotype, combined GS7M1 and GS7T1 genotypes as well as the combination of CYP1A1 and GS7T1 genotypes may be used as susceptible markers for asthma.
Chung, Hai Won,Kang, Su Jin,Lee, Young Joon,Kim, Su Young 대한방사선 방어학회 2002 방사선방어학회지 Vol.27 No.2
The interaction of low density extremely low frequency magnetic field (ELE MF)in the frequency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) mutation induced by bleomycin and on the frequency of sister chromatid exchanges (SCEs) induced by 1,2,4-benzenetriol(BT) was demonstrated. CHO cells pretreated with bleomycin or 1,2,4-benzenetriol were exposed for 24hrs to a sinusoidal 0.8mT magnetic field at 60Hz. Frequency of HPRT mutation and SCEs were determined. ELF MF exposure led to a two-fold increase of the frequency of HPRT mutation induced by bleomycin. No increase of mutation frequency was observed by ELF MF alone. ELF MF also increased the frequency of SCEs induced by BT while no increase of SCE frequencies were observed by ELF MF alone. These results suggest that low density ELF MF field would act as an enhancer rather than as an initiator of mutagenic effects in CHO cell.
Chung, Hai-Won,Kang, Su-Jin,Lee, Young-Joon,Kim, Su-Young The Korean Association for Radiation Protection 2002 방사선방어학회지 Vol.27 No.2
The interaction of low density extremely low frequency magnetic field (ELF MF) in the frequency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) mutation induced by bleomycin and on the frequency of sister chromatid exchanges (SCEs) induced by 1,2,4-benzenetriol(BT) was demonstrated. CHO cells pretreated with bleomycin or 1,2,4-benzenetriol were exposed for 24hrs to a sinusoidal 0.8mT magnetic field at 60Hz. Frequency of HPRT mutation and SCEs were determined. ELF MF exposure led to a two-fold increase of the frequency of HPRT mutation induced by bleomycin. No increase of mutation frequency was observed by ELF MF alone ELF MF also increased the frequency of SCEs induced by BT while no Increase of SCE frequencies were observed by ELF MF alone. These results suggest that low density ELF MF field would art as an enhancer rather than as an initiator of mutagenic effects in CHO cell.