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RISS 인기검색어
- 검색키워드
- 저자 : Haeni Seo (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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Scutellaria baicalensis Extract Alleviates Pain and Inflammation in Animal Models
Haeni Seo,Ho-Sueb Song 대한침구의학회 2023 대한침구의학회지 Vol.40 No.1
Background: This study aimed to examine the effect of Scutellaria baicalensis extract (SBE) on ameliorating pain response and inflammation in an animal model. Methods: The effects of SBE on joint inflammation-induced rats and pain writhing response were measured. In rats with monosodium iodoacetate (MIA)-induced knee osteoarthritis (OA), the weight-bearing distribution of the hind legs was measured, the actual joint condition was visually confirmed, and serum cytokines were extracted from whole blood and measured. In addition, the acetic acid-induced pain was measured by the number of abdominal wall contractions and writhing responses. Results: 1. The weight-bearing distribution of the hind limbs of the SBE group was remarkably improved compared with that of the control group 7 days after MIA treatment, and the SBE 300 group was improved similarly to that of the indomethacin group. 2. Cartilage erosion was significantly recovered in the SBE and indomethacin groups, and the degree of healing of cartilage erosion by SBE was similar to that by indomethacin. 3. The serum levels of cytokines interleukin-1β, tumor necrosis factor-α, and interleukin-6 were significantly decreased in the SBE group compared with that in the control group, and the SBE 300 group had reduced levels of cytokines similar to the indomethacin group. 4. As regards acetic acid-induced writhing response, the number of writhes was significantly reduced in the SBE and ibuprofen groups, and the SBE 600 group had fewer writhes than the ibuprofen group. Conclusion: SBE significantly improves knee OA and pain and is expected to show similar therapeutic effects to indomethacin and ibuprofen.
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김해니,박호원,이주현,서현우,Kim, Haeni,Park, Howon,Lee, Juhyun,Seo, Hyunwoo Korean Academy of Pediatric Dentistry 2021 大韓小兒齒科學會誌 Vol.48 No.4
이 연구의 목적은 알카자이트 수복재와 자이오머에서 방출되는 불소가 상아질 접착층을 투과하는 유리되는 양을 측정하고 비교하는 것이었다. 알카자이트 수복재와 자이오머 및 불소 미함유 복합레진의 시편을 각 재료 당 20개씩 제작하여 그 중 10개의 시편에 상아질 접착제를 도포하였다. 만들어진 시편을 2.0 mL의 탈이온수가 들어있는 폴리에틸렌튜브에 넣고 37.0℃ 항온수조에 연구 기간동안 보관하였다. 보관 후 1일, 3일, 7일, 14일, 21일, 28일째에 불소 유리량을 측정하였으며 매 측정 후 탈이온수를 교체하였다. 상아질 접착제층 두께의 적절성은 시편을 추가로 제작하여 전계방사형 주사전자현미경으로 관찰하여 평가하였다. 알카자이트 수복재와 자이오머에 상아질 접착제를 도포한 경우 접착제가 불소의 유리를 완전히 차단하지는 않았지만, 유리된 불소의 양이 현저히 감소하였다. 28일간 측정한 알카자이트 수복재의 불소 유리량은 상아질 접착제의 유무와 관계없이 자이오머보다 크게 나타났다. This study evaluated the fluoride release of alkasite restorative material (ARM) and giomer penetrating the dentin adhesive layer. Twenty specimens were prepared for each restorative material, and dentin adhesive with uniform thickness was applied to half of them. The prepared specimens were placed in a polyethylene tube containing 2.0 mL of deionized water and deposited in a 37.0℃ water bath for the study duration. The amount of fluoride release was measured on the 1<sup>st</sup>, 3<sup>rd</sup>, 7<sup>th</sup>, 14<sup>th</sup>, 21<sup>st</sup>, and 28<sup>th</sup> days after deposition. The dentin adhesive applied to the ARM and giomer could not completely block the fluoride release; however, it significantly reduced its amount. The cumulative amount of fluoride release of the ARM after 28 days was higher than that of the giomer regardless of the application of dentin adhesive.
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Jung Min Son,Hye Soo Youn,Eun Chang Lee,Choong Hyun Park,Sun Woo Kwon,Ji Yoon Lee,Da Young Han,Haeni Seo 대한침구의학회 2023 대한침구의학회지 Vol.40 No.1
This study individually analyzed the effects of Korean Facial Chuna Manual Treatment (K-FCMT) combined with Korean medicine (KM) treatment (acupuncture, electroacupuncture, pharmacopuncture, and herbal medicine) on five patients with acute Bell’s palsy who visited Dongsuwon Korean Medicine Hospital between August 1 and 31, 2022. During inpatient treatment, two of the five patients received K-FCMT 5–6 times a week, and the other three received the same frequency during outpatient treatment for approximately 2 weeks. Patients with a House–Brackmann grading scale (HBGS) score of ≤4 and Yanagihara unweighted grading system (Y-score) ≥7–8 began to recover after the 2nd–3rd sessions of K-FCMT, which entered the recovery phase quickly. As patients entered the recovery phase (7–9th sessions of K-FCMT), symptoms improved to HBGS scores of 1–2 and Y-scores of 35–40 points. This study suggests the possibility of applying K-FCMT combined with KM treatment to patients in the acute stage of Bell’s palsy.
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