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Ha, Tae-Woong,Lee, An-Sung The Korean Society of Mechanical Engineers 2000 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.14 No.3
In this paper the leakage prediction and rotordynamic analysis of an annular seal with a smooth rotor and circumferentially grooved stator are performed based on a three-controlvolume theory. The present analysis is validated by comparing with the experimental data of Iwatsubo and Sheng and theoretical results suggested by Marquette and Childs. For the leakage prediction the present analysis shows a good agreement with Marquette and Childs' result and a qualitation agreement with Iwatsubo and Shengs' experimental data. Direct and cross-coupled stiffness coefficients show closer agreement with the experimental values than those of Marquette and Childs. However, direct damping coefficient shows greater discrepancy from the experimental value than Marquette and Childs'.
Design for a Simplified Cochlear Implant System
An, Soon Kwan,Kim, Sung June,Park, Se-Ik,Jun, Sang Beom,Lee, Choong Jae,Byun, Kyung Min,Sung, Jung Hyun,Wilson, Blake S.,Rebscher, Stephen J.,Oh, Seung Ha IEEE 2007 IEEE Transactions on Biomedical Engineering Vol.54 No.6
<P>A simplified cochlear implant (CI) system would be appropriate for widespread use in developing countries. Here, we describe a CI that we have designed to realize such a concept. The system implements 8 channels of processing and stimulation using the continuous interleaved sampling (CIS) strategy. A generic digital signal processing (DSP) chip is used for the processing, and the filtering functions are performed with a fast Fourier transform (FFT) of a microphone or other input. Data derived from the processing are transmitted through an inductive link using pulse width modulation (PWM) encoding and amplitude shift keying (ASK) modulation. The same link is used in the reverse direction for backward telemetry of electrode and system information. A custom receiver-stimulator chip has been developed that demodulates incoming data using pulse counting and produces charge balanced biphasic pulses at 1000 pulses/s/electrode. This chip is encased in a titanium package that is hermetically sealed using a simple but effective method. A low cost metal-silicon hybrid mold has been developed for fabricating an intracochlear electrode array with 16 ball-shaped stimulating contacts</P>
Effect of microwave irradiation on lipase-catalyzed reactions in ionic liquids
An, Gwangmin,Kim, Young Min,Koo, Yoon-Mo,Ha, Sung Ho The Korean Society of Analytical Science 2017 분석과학 Vol.30 No.3
Microwave-assisted organic synthesis has gained a remarkable interest over the past years because of its advantages - (i) rapid energy transfer and superheating, (ii) higher yield and rapid reaction, (iii) cleaner reactions. Ionic liquids are well known for their unique properties such as negligible vapor pressure and high thermal stability. With these properties, ionic liquids have gained increasing attention as green, multi-use reaction media. Recently, ionic liquids have been applied as reaction media for biocatalysis. Lipase-catalyzed reactions in ionic liquids provide high activity and yield compared to conventional organic solvents or solvent free system. Since polar molecules are generally good absorbent to microwave radiation, ionic liquids were investigated as reaction media to improve activity and productivity. In this study, therefore, the effect of microwave irradiation in ionic liquids was investigated on lipase catalyzed reactions such as benzyl acetate synthesis and caffeic acid phenethyl ester synthesis. Comparing to conventional heating, microwave heating showed almost the same final conversion but increased initial reaction rate (3.03 mM/min) compared to 2.11 mM/min in conventional heating at $50^{\circ}C$.
Comparison Study of Oxidation Behavior of Low Carbon Steel at Elevated Temperatures
Ha, Sang An,Kim, Dong Kyun,Lee, Woo Jin,Kang, Chang Yong,Kim, Kwon Hoo,Wang, Jei Pil Trans Tech Publications, Ltd. 2014 Advanced materials research Vol.1025 No.-
<P>Comparison study of oxidation behavior of low carbon steel was conducted at the temperature range of 500°C to 700°C under a 0.2 atm oxygen pressure by continuous and discontinuous oxidation methods. Oxidation rate of both cases was found to be increased with increasing temperature from 500°C to 700°C and obeyed parabolic rate law. In addition, activation energy for the continuous oxidation of steel was found to be a 164.8 kJ/mole, which means that oxidation rate is proportionally dependant on temperature. In case of cyclic oxidation, the oxidation rate was shown to faster than continuous oxidation at all temperatures due to direction oxidation through spallation of the oxide layer.</P>
Transduced PEP-1-Grb7 Fusion Protein Suppressed LPS-induced COX-2 Expression
An, Jae-Jin,Kim, So-Young,Lee, Sun-Hwa,Kim, Dae-Won,Ryu, Hea-Jin,Yeo, Seung-Il,Jang, Sang-Ho,Kwon, Hyung-Joo,Kim, Tae-Yoon,Lee, Sang-Chul,Poo, Ha-Ryoung,Cho, Sung-Woo,Lee, Kil-Soo,Park, Jin-Seu,Eum, W Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.2
Although the incidence and severity of atopic dermatitis (AD) is steadily increasing at an alarming rate, its pathogenic mechanisms remain poorly understood yet. Recently, we found that the expression of Grb7 protein was markedly decreased in AD patients using proteomic analysis. In the present study, human Grb7 gene was fused with PEP-1 peptide in a bacterial expression vector to produce a genetic in-frame PEP-1-Grb7 fusion protein. The expressed and purified PEP-1-Grb7 fusion proteins transduced efficiently into skin cells in a time- and dose-dependent manner when added exogenously in culture media. Once inside the cells, the transduced PEP-1-Grb7 protein was stable for 48 h. In addition, transduced PEP-1-Grb7 fusion protein markedly increased cell viability in macrophage RAW 264.7 cells treated with LPS by inhibition of the COX-2 expression level. These results suggest that the PEP-1-Grb7 fusion protein can be used in protein therapy for inflammatory skin disorders, including AD.
An, Ha-Rim,Oh, Sung-Tag,Kim, Chang Yeoul,Baek, Seong-Ho,Park, Il-Kyu,Ahn, Hyo-Jin Elsevier 2014 Journal of Alloys and Compounds Vol.615 No.-
<P><B>Abstract</B></P> <P>Al-doped ZnO (AZO)/Ag grid hybrid transparent conductive electrode (TCE) structures were fabricated at a low temperature by using electrohydrodynamic jet printing for the Ag grids and atomic layer deposition for the AZO layers. The structural investigations showed that the AZO/Ag grid hybrid structures consisted of Ag grid lines formed by Ag particles and the AZO layer covering the inter-spacing between the Ag grid lines. The Ag particles comprising the Ag grid lines were also capped by thin AZO layers, and the coverage of the AZO layers was increased with increasing the thickness of the AZO layer. Using the optimum thickness of AZO layer of 70nm, the hybrid TCE structure showed an electrical resistivity of 5.45×10<SUP>−5</SUP> Ωcm, an optical transmittance of 80.80%, and a figure of merit value of 1.41×10<SUP>−2</SUP> Ω<SUP>−1</SUP>. The performance enhancement was suggested based on the microstructural investigations on the AZO/Ag grid hybrid structures.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Al-doped ZnO/Ag transparent conductive electrode is fabricated at low temperature. </LI> <LI> Performance of the hybrid transparent conductive electrode affected by the structure. </LI> <LI> The performance enhancement mechanism is suggested. </LI> </UL> </P>