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      • KCI등재

        Evaluation of Antioxidant and Antimicrobial Potential of Strawberry Tree (Arbutus Unedo L.) Leaf

        Hakime Hülya Orak,Hülya Yagar,Sebnem Selen Isbilir,Ahmet Şükrü Demirci,Tuncay Gümüş,Neslihan Ekinci 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.5

        In present study, antioxidant and antimicrobial activities of strawberry tree (Arbutus unedo L.) leaves were investigated. Antioxidant activity was determined by methods of DPPH scavenging, β-carotene bleaching,reducing power, metal chelating, superoxide anion scavenging, and hydrogen peroxide scavenging activity. Total phenolic content were determined to be 197.16±1.43mg GAE/g extract in aqueous extract. The EC_50 value of methanolic extracts was found to be 0.423 mg/mL. The extracts of leaves showed nearly 1/4 metal chelating capacity of standard EDTA, high reducing power,superoxide anion scavenging, and hydrogen peroxide scavenging activities. While the strawberry tree leaves exhibited antibacterial activity against Staphylococcus aureus, there was no inhibitory effect against Escherichia coli and Salmonella enteritidis. The strawberry tree leaves exhibited antifungal effect against 2 aflatoxigenic molds namely Aspergillus parasiticus NRRL 2999 and NRRL 465. These results suggest that the strawberry tree leaves may be used as an antioxidant source for pharmaceutical application, nutraceutical and functional food industries.

      • KCI등재

        Morphological similarity of a tri-block copolymer processed at ambient and elevated temperatures

        Sebnem Inceoglu,Taner Aytun,Yusuf Z. Mencelo lu,lhan Özen,Metin H. Acar 한국유변학회 2012 Korea-Australia rheology journal Vol.24 No.4

        We investigated the effect of temperature on the morphology of a tri-block copolymer (BCP) processed in a capillary rheometer. The material used was a polystyrene-b-poly(2-ethylhexyl acrylate)-b-polystyrene (PS-b-PEHA-b-PS) tri-block copolymer, which was synthesized by ATRP with a molecular weight of 38.5 K consisting of 49 molar % PEHA. According to the rheological data obtained with dynamic viscoelastic oscillatory measurements, order-disorder temperature (ODT) of the BCP was measured at around 110oC. Considering this observation, the samples were studied under different temperatures and pressures (from 110°C to 28°C and from 48 to 75 bar) in capillary rheometer. All processed materials were characterized by using differential scanning calorimetry (DSC) and atomic force microscopy (AFM). It was found that all samples processed by aid of either temperature or pressure showed similar mixed morphologies (a mixture of the ordered and disordered structures i.e., the reduction of microphase separation due to processing).

      • SCIESCOPUSKCI등재

        Morphological similarity of a tri-block copolymer processed at ambient and elevated temperatures

        Inceoglu, Sebnem,Aytun, Taner,Menceloglu, Yusuf Z.,Ozen, Ilhan,Acar, Metin H. 한국유변학회 2012 Korea-Australia rheology journal Vol.24 No.4

        We investigated the effect of temperature on the morphology of a tri-block copolymer (BCP) processed in a capillary rheometer. The material used was a polystyrene-b-poly(2-ethylhexyl acrylate)-b-polystyrene (PS-b-PEHA-b-PS) tri-block copolymer, which was synthesized by ATRP with a molecular weight of 38.5 K consisting of 49 molar % PEHA. According to the rheological data obtained with dynamic viscoelastic oscillatory measurements, order-disorder temperature (ODT) of the BCP was measured at around $110^{\circ}C$. Considering this observation, the samples were studied under different temperatures and pressures (from $110^{\circ}C$ to $28^{\circ}C$ and from 48 to 75 bar) in capillary rheometer. All processed materials were characterized by using differential scanning calorimetry (DSC) and atomic force microscopy (AFM). It was found that all samples processed by aid of either temperature or pressure showed similar mixed morphologies (a mixture of the ordered and disordered structures i.e., the reduction of microphase separation due to processing).

      • KCI등재

        Spatial Analysis of Two-Wheeled Vehicles Traffic Crashes: Osmaniye in Turkey

        Guler Yalcin,H.Sebnem Duzgun 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.7

        To achieve a sustainable traffic management and sustainable transportation planning in urban areas one of the tools that can be used effectively is Geographic Information Systems. In Turkey Transportation Department under Civil Engineering deals with roads and railways which are open to public such as inner city and outer city traffic arrangements with General Directorate of Security. This paper aims to analyze road traffic accident distribution according to the vehicle types involved in the accidents for urban areas in sample of Osmaniye, Turkey. While chi-square test is used for non-spatial analysis kernel density, nearest neighbor distances and Kfunction analysis are applied to determine the existence of clustering and hotspots. The network statistics are executed through SANET (Spatial Analysis on a NETwork) V4.1 that runs on ArcMap 10 and for better visualization and understanding the analysis 3D analysis are generated in ArcScene 10. It is realized that the accidents involving two-wheeled vehicles have a high percentage in all accidents. Also the possible reasons to use two-wheeled vehicles at a high rate in the city center are searched by Location Quotient Technique. The importance of this study is to use GIS as a management system for accident analysis with statistical analysis methods.

      • KCI등재

        Clinicopathologic Characteristics and Therapeutic Outcomes of Primary Gastrointestinal Non-Hodgkin's Lymphomas in Central Anatolia, in Turkey

        Bulent Eser,Bunyamin Kaplan,Ali Unal,Ozlem Canoz,Fevzi Altuntas,H. Ismail. Sari,Ozlem Er,Metin Ozkan,Can Kucuk,Makbule Arar,Sebnem Gursoy,Mustafa Cetin 연세대학교의과대학 2006 Yonsei medical journal Vol.47 No.1

        We carried out a retrospective analysis of 74 patients who were presented to our center with histopathological diagnosis of primary gastro-intestinal non-Hodgkin's lymphoma between 1990 and 2001. All patients have been staged according to Lugano Staging System. For histopathological classification, International Working Formulation was applied. The treatment choice concerning the surgical or non-surgical management was decided by the initially acting physician. Treatment modalities were compared using the parameters of age, sex, histopathological results, stage, and the site of disease. Of the 74 patients, 31 werefemale and 43 were male, with a median age of 49 years (range 15-80). The stomach was the most common primary site and was seenin 51 of 74 patients (68.9%). The intermediate and high grade lymphomas constituted 91.9% of the all cases. In a median follow-up of 29 months (range 2-128), 20 out of 74 patients died. There was a three year overall survival rate in 65.4% of all patients. The three year overall survival rate was better in stage I and II1 patients who were treated with surgery plus chemotherapy (+/-RT) than those treated with chemotherapy alone (93.7% vs. 55.6%, p 0.05). The stage and presence of B symptoms affected the disease free survival and overall survival significantly, but the histopathologic grade only affected the overall survival. On the basis of these results, we suggest that surgicalresection is necessary before chemotherapy in early stage (stage I and II1) patients with gastrointestinal non-Hodgkin's lymphomas because of the significant survival advantage it would bring to the patient.

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