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      • KCI등재후보

        Approximation by Means of Fourier Trigonometric Series in Weighted Orlicz Spaces

        Guven,Israfilov 장전수학회 2009 Advanced Studies in Contemporary Mathematics Vol.19 No.2

        The order of approximation of Cesaro, Zygmund and Abel-Poisson means of Fourier trigonometric series were estimated by the modulus of continuity in re‡exive weighted Orlicz spaces with Muckenhoupt weights. These results were applied to estimate the rate of approximation of Cesaro, Zygmund and Abel sums of Faber series in weighted Smirnov-Orlicz classes de…ned on simply connected domains of the complex plane.

      • KCI등재

        Effects of Various Inhibitors on β-galactosidase Purified from the Thermoacidophilic Alicyclobacillus acidocaldarius Subsp. Rittmannii Isolated from Antarctica

        Reyhan Gul Guven,Alevcan Kaplan,Kemal Guven,Fatma Matpan,Mehmet Dogru 한국생물공학회 2011 Biotechnology and Bioprocess Engineering Vol.16 No.1

        β-Galactosidase purified from the thermoacidophilic Alicyclobacillus acidocaldarius subsp. rittmannii isolated from Antarctica is a member of the GH42 family. The enzyme was not effected by various concentrations of its reaction product glucose, but was greatly inhibited by the other reaction product galactose using both substrates,ONPG and lactose. Linewever-Burk plot analysis derived from both ONPG and lactose hydrolysis results showed that galactose is a mixed-type inhibitor of the purified β-galactosidase. The enzyme was slightly activated by Mg^(2+)(13% at 20 mM), while inhibited at higher concentrations of Ca^(+2) (33% at 10 mM), Zn^(+2) (86% at 8 mM) and Cu^(+2)(87% at 4 mM). The enzyme activity was not significantly altered by the metal ion chelators EDTA and 1,10-phenanthroline up to 20 mM, indicating that this enzyme is not a metalloenzyme. 2-Mercaptoethanol and DTT were found to enhance β-galactosidase activity, while p-chloromercuribenzoic acid (PCMB) completely inhibited enzymatic activity (97% at 1 mM; 99.7% at 2 mM), indicating at least one essential Cys residue modified by the reagents in the active site of β-galactosidase. Iodoacetamide and Nethylmaleimide had little effect on the β-galactosidase. Phenylmethylsulfonyl fluoride (PMSF) inhibited the enzyme strongly (19.8% at 1 mM; 71.9% at 10 mM), also showing the participation of serine for enzyme activity.

      • KCI등재

        Behavior and design of stainless steel tubular member welded end connections

        Guven Kiymaz,Edip Seckin 국제구조공학회 2014 Steel and Composite Structures, An International J Vol.17 No.3

        Among the various alternatives to make a steel tubular member connection, making a slotted and gusset plate welded connection is one of the most frequently preferred alternatives. This type of connection is essentially an end connection that is made by slotting the tube longitudinally, inserting the gusset plate and then placing longitudinal fillet welds at the tube-to-plate interface. In this paper an experimental study on the behaviour of such connections in stainless steel is presented. 24 specimens were tested under concentrically applied axial tensile forces for varying tube-to-gusset plate weld lengths. Both circular and box section members were considered in the test program. Load-deformation curves were obtained and comparisons were made in terms of strength and ductility. The results obtained from the study were then critically examined and compared with currently available design guidance for slotted gusset plate welded tubular end connections. It is noted that no specific rules exist in international specifications on structural stainless steel which cover the design of such connections. Therefore, the results of this study are compared with the existing design rules for carbon steel.

      • SCIESCOPUSKCI등재

        Comparison of retention forces with various fabrication methods and materials in double crowns

        Guven, Melahat Celik,Tuna, Meral,Bozdag, Ergun,Ozturk, Gizem Nur,Bayraktar, Gulsen The Korean Academy of Prosthodonitics 2017 The Journal of Advanced Prosthodontics Vol.9 No.4

        PURPOSE. The purpose of this study was to analyze the retention force changes and wear behaviours of double-crown systems over long-term use. MATERIALS AND METHODS. Ten groups, each consisting of six samples, were evaluated. Specifically, casting gold alloy primary crown - casting gold alloy secondary crown (AA), laser sintering primary crown - laser sintering secondary crown (LL), casting Cr alloy primary crown - casting Cr alloy secondary crown, (CC) zirconia primary crown - electroformed secondary crown (ZA), and CAD/CAM titanium alloy primary crown - CAD/CAM titanium alloy secondary crown (TT) groups were evaluated at cone angles of $4^{\circ}$ and $6^{\circ}$. The samples were subjected to 5,000 insertion-separation cycles in artificial saliva, and the retention forces were measured every 500 cycles. The wear levels were analyzed via SEM at the beginning and end of the 5,000 cycles. RESULTS. In all samples, the retention forces increased when the conus angle decreased. The highest initial and final retention force values were found in the $LL-4^{\circ}$ group (32.89 N-32.65 N), and the lowest retention force values were found in the $ZA6^{\circ}$ group (5.41 N-6.27 N). The ZA groups' samples showed the least change in the retention force, and no wear was observed. In the other groups, wear was observed mostly in the primary crowns. CONCLUSION. More predictable, clinically relevant, and less excursive retention forces can be observed in the ZA groups. The retention force values of the LL groups were statically similar to those of the other groups, except the ZA groups.

      • SCIESCOPUSKCI등재

        MULTIPLIER THEOREMS IN WEIGHTED SMIRNOV SPACES

        Guven, Ali,Israfilov, Daniyal M. Korean Mathematical Society 2008 대한수학회지 Vol.45 No.6

        The analogues of Marcinkiewicz multiplier theorem and Littlewood-Paley theorem are proved for p-Faber series in weighted Smirnov spaces defined on bounded and unbounded components of a rectifiable Jordan curve.

      • SCOPUSSCIEKCI등재

        The Neuroprotective Effect of Kefir on Spinal Cord Ischemia/Reperfusion Injury in Rats

        Guven, Mustafa,Akman, Tarik,Yener, Ali Umit,Sehitoglu, Muserref Hilal,Yuksel, Yasemin,Cosar, Murat The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.57 No.5

        Objective : The main causes of spinal cord ischemia are a variety of vascular pathologies causing acute arterial occlusions. We investigated neuro-protective effects of kefir on spinal cord ischemia injury in rats. Methods : Rats were divided into three groups : 1) sham operated control rats; 2) spinal cord ischemia group fed on a standard diet without kefir pretreatment; and 3) spinal cord ischemia group fed on a standard diet plus kefir. Spinal cord ischemia was performed by the infrarenal aorta cross-clamping model. The spinal cord was removed after the procedure. The biochemical and histopathological changes were observed within the samples. Functional assessment was performed for neurological deficit scores. Results : The kefir group was compared with the ischemia group, a significant decrease in malondialdehyde levels was observed (p<0.05). Catalase and superoxide dismutase levels of the kefir group were significantly higher than ischemia group (p<0.05). In histopathological samples, the kefir group is compared with ischemia group, there was a significant decrease in numbers of dead and degenerated neurons (p<0.05). In immunohistochemical staining, hipoxia-inducible factor-$1{\alpha}$ and caspase 3 immunopositive neurons were significantly decreased in kefir group compared with ischemia group (p<0.05). The neurological deficit scores of kefir group were significantly higher than ischemia group at 24 h (p<0.05). Conclusion : Our study revealed that kefir pretreatment in spinal cord ischemia/reperfusion reduced oxidative stress and neuronal degeneration as a neuroprotective agent. Ultrastructural studies are required in order for kefir to be developed as a promising therapeutic agent to be utilized for human spinal cord ischemia in the future.

      • KCI등재

        Ultrasound-guided PENG block versus intraarticular corticosteroid injection in hip osteoarthritis: a randomised controlled study

        Selin Guven Kose,Halil Cihan Kose,Feyza Celikel,Serkan Tulgar,Omer Taylan Akkaya 대한통증학회 2023 The Korean Journal of Pain Vol.36 No.2

        Background: This study aimed to compare the effectiveness of the pericapsular nerve group (PENG) block and intra-articular injection (IAI) of steroid-bupivacaine in the treatment of hip osteoarthritis (OA). Methods: After randomization, patients received either a PENG block or IAI under ultrasound-guidance. Clinical evaluations were recorded at baseline, day 1, and weeks 1, 4, and 8 post-intervention. The numerical rating scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), Harris Hip Scale (HHS) scores, pain medication use determined by a quantitative analgesic questionnaire, and patient satisfaction were evaluated. Results: Sixty patients were included in this study. NRS scores improved significantly for both groups during the follow-up compared to pretreatment (P < 0.001), with better pain scores for the PENG group (P < 0.001) at day 1 with larger effect size (Cohen’s d = 4.62), and IAI group at 4 (Cohen’s d = 5.15) and 8 (Cohen’s d = 4.33) weeks (P < 0.001). There was no significant difference in pain medication consumption (P = 0.499) and patient satisfaction (P = 0.138) between groups. Patients in the IAI group experienced significant improvement in HHS (Cohen’s d = 2.16, P = 0.007) and WOMAC (Cohen’s d = 1.02, P = 0.036) scores at 8 weeks compared to the PENG group. Conclusions: The ultrasound-guided PENG block provides effective pain relief which improves functionality and quality of life in hip OA patients up to 2 months. The PENG block can be considered an easy, safe, and useful alternative treatment modality for hip OA.

      • KCI등재

        Multiplier theorems in weighted Smirnov spaces

        Ali Guven,Daniyal M. Israfilov 대한수학회 2008 대한수학회지 Vol.45 No.6

        The analogues of Marcinkiewicz multiplier theorem and Littlewood- Paley theorem are proved for p-Faber series in weighted Smirnov spaces defined on bounded and unbounded components of a rectifiable Jordan curve. The analogues of Marcinkiewicz multiplier theorem and Littlewood- Paley theorem are proved for p-Faber series in weighted Smirnov spaces defined on bounded and unbounded components of a rectifiable Jordan curve.

      • KCI등재

        Equality in degrees of compactness: Schauder's theorem and $s$-numbers

        Asuman Guven Aksoy,Daniel Akech Thiong 대한수학회 2023 대한수학회논문집 Vol.38 No.4

        We investigate an extension of Schauder's theorem by studying the relationship between various $s$-numbers of an operator $T$ and its adjoint $T^*$. We have three main results. First, we present a new proof that the approximation number of $T$ and $T^*$ are equal for compact operators. Second, for non-compact, bounded linear operators from $X$ to $Y$, we obtain a relationship between certain $s$-numbers of $T$ and $T^*$ under natural conditions on $X$ and $Y$. Lastly, for non-compact operators that are compact with respect to certain approximation schemes, we prove results for comparing the degree of compactness of $T$ with that of its adjoint $T^*$.

      • KCI등재

        Predictive factors associated with successful response to utrasound guided genicular radiofrequency ablation

        Selin Guven Kose,Halil Cihan Kose,Feyza Celikel,Omer Taylan Akkaya 대한통증학회 2022 The Korean Journal of Pain Vol.35 No.4

        Background: Ultrasound-guided genicular nerve radiofrequency (RF) procedures are of interest in the management of chronic knee pain. A wide variety of demographic, clinical, and procedural characteristics can affect treatment success. This study aimed to determine predictive factors to provide superior treatment outcomes. Methods: The demographic, clinical, and technical data of patients who received genicular nerve RF for knee pain between September 2016 and September 2021 were evaluated. A positive outcome was defined as at least 50% pain relief on a pain score for at least 6 months. Logistic regression analysis was performed to determine the factors associated with a successful response to genicular RF. Results: Among 206 patients who underwent genicular RF, 62% of the patients reported successful outcomes at 6 months. In the multivariate model, targeting 5 nerves (odds ratio [OR], 6.184; 95% confidence interval [CI], 2.291–16.690; P < 0.001) was the most significant predictor of successful outcomes. Multivariable logistic regression analysis showed that prognostic genicular nerve block with a 50% cut-off value (OR, 2.109; 95% CI, 1.038–4.287; P = 0.039), no opioid use (OR, 2.753; 95% CI, 1.405–5.393; P = 0.003), and depression (OR, 0.297; 95% CI, 0.124–0.713; P = 0.007) were the predictive factors significantly associated with response to genicular RF. Conclusions: Clinical and technical factors associated with better treatment outcomes were ultimately targeting more nerves, performing prognostic block, no opioid use, and no depression. These results are expected to be considered when selecting patients for genicular RF.

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