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- 저자 : Guoping Yu (검색결과 2 건)
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Yuxin Wang,Guoping Yu,Anmin Sun,Xinghang Cai,Chonghui Yue 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.5
Effects of different hydrolytic conditions on functional ingredient contents and antioxidant activities of aqueous enzymatic extracts from rice bran (AEERB) were evaluated and correlations were determined. After trypsin hydrolysis under weak alkalescent conditions, the soluble protein, total phenolic, α-tocopherol, and γ-oryzanol contents of AEERB were increased. Excessively high temperatures (>60℃) and long hydrolysis times (>2.0 h) were not suitable for enzymatic hydrolysis. The free radical scavenging activity, ferric reducing/antioxidant power, lipid peroxidation inhibition activity, and total antioxidant activity were used for evaluation of the antioxidant activity. AEERB displayed an antioxidant activity and correlations of concentration levels of functional ingredients with antioxidant activity were significantly (p<0.05) positive.
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Erdheim-Chester Disease with Emperipolesis: A Unique Case Involving the Heart
Pengcheng Zhu,Naping Li,Lu Yu,Mariajose Navia Miranda,Guoping Wang,Yaqi Duan 대한암학회 2017 Cancer Research and Treatment Vol.49 No.2
Histiocytosis is an uncommon disease characterized by excessive accumulation of histiocytes. Here, we report a rare case of non-Langerhans-cell histiocytosis in a 51- year-old woman who presented with severe symptoms of pericardial effusion. Radiologic investigation also detected multiple bone (lower limbs, vertebrae, ribs, and ilium) lesions. Resected pericardium showed abundant mono- or multi-nucleated non-foamy histiocytes (CD68+/CD163+/S-100+/CD1/langerin) in a fibroinflammatory background. The histiocytes demonstrated emperipolesis of lymphocytes, a hallmark feature of Rosai-Dorfman disease (RDD). However, molecular analysis revealed a BRAF V600E mutation of the proliferating histiocytes, highlighting the neoplastic features frequently observed in another non-Langerhans-cell histiocytosis known as Erdheim- Chester Disease (ECD). We consider this case to be a unique presentation of ECD harboring some RDD-like cells with emperipolesis, but not a case of RDD with a BRAF mutation concerning its clinical manifestation (involvement of the heart and bones) and neoplastic features.
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