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Crack-tip constraint analysis of two collinear cracks under creep condition
Guang-Chen Jiao,Wei-Zhe Wang,Pu-Ning Jiang 국제구조공학회 2012 Structural Engineering and Mechanics, An Int'l Jou Vol.43 No.3
The higher-order asymptotic C(t) − A2(t) approach was employed to investigate the crack-tip stress of two collinear cracks in a power-law creeping material under the plane strain conditions. A comprehensive calculation was made of the single crack, collinear crack model with S/a = 0.4 and 0.8, by using the C(t) − A2(t) approach, HRR-type field and the finite element analysis; the latter two methods were used to check the constraint significance and the calculation accuracy of the C(t) − A2(t) approach,respectively. With increasing the creep time, the constraint A2 was exponentially increased in the smallscale creep stage, while no discernible dependency of the constraint A2 on the creep time was found at the extensive creep state. In addition, the creep time and the mechanical loads have no distinct influence on accuracy of the results obtained from the higher-order asymptotic C(t) − A2(t) approach. In comparison with the HRR-type field, the higher-order asymptotic C(t) − A2(t) solution matches well with the finite element results for the collinear crack model.
Crack-tip constraint analysis of two collinear cracks under creep condition
Jiao, Guang-Chen,Wang, Wei-Zhe,Jiang, Pu-Ning Techno-Press 2012 Structural Engineering and Mechanics, An Int'l Jou Vol.43 No.3
The higher-order asymptotic C(t) - $A_2(t)$ approach was employed to investigate the crack-tip stress of two collinear cracks in a power-law creeping material under the plane strain conditions. A comprehensive calculation was made of the single crack, collinear crack model with S/a = 0.4 and 0.8, by using the C(t) - $A_2(t)$ approach, HRR-type field and the finite element analysis; the latter two methods were used to check the constraint significance and the calculation accuracy of the C(t) - $A_2(t)$ approach, respectively. With increasing the creep time, the constraint $A_2$ was exponentially increased in the small-scale creep stage, while no discernible dependency of the constraint $A_2$ on the creep time was found at the extensive creep state. In addition, the creep time and the mechanical loads have no distinct influence on accuracy of the results obtained from the higher-order asymptotic C(t) - $A_2(t)$ approach. In comparison with the HRR-type field, the higher-order asymptotic C(t) - $A_2(t)$ solution matches well with the finite element results for the collinear crack model.
Jian-Fang Liu,Xu-Guang Sun,Xiaoyang Jiao,Hong-Xia Chen,Shun-Ming Hua,Hong-Chun Zhang 대한기계학회 2013 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.27 No.2
To levitate ICF target spheres in the near-field acoustic levitation, a transducer with concave spherical radiating surface and a near-field acoustic levitation system is established. The concave spherical radiating surface of the transducer is designed by the finite element parametric method. Then the levitation height and levitation perturbation of spheres with different mass and diameters in the near-field acoustic levitation system are tested and discussed in the driving voltage at 400V, 500V and 600V, respectively, when the levitation system is under the resonant frequency. Finally, based on the experimental results, the height formula of the near-field acoustic levitation for spheres is deduced by introducing a coupling coefficient.
Feixia Zhan,Chao Zhang,Shige Wang,Zeyu Zhu,Guang-Chen Jiao,Mingliang Zhao,Li Cao 대한신경과학회 2020 Journal of Clinical Neurology Vol.16 No.2
Background and Purpose Hyperekplexia (HPX), a rare neurogenetic disorder, is classically characterized by neonatal hypertonia, exaggerated startle response provoked by the sudden external stimuli and followed by a shortly general stiffness. Glycine receptor alpha 1 (GLRA1) is the major pathogenic gene of the disease. We described the clinical manifestations of genetically confirmed HPX patients and made a literature review of GLRA1-related HPX to improve the early recognition and prompt the management of the disorder. Methods Extensive clinical evaluations were analyzed in 4 Chinese HPX patients from two unrelated families. Next generation sequencing was conducted in the probands. Sanger sequence and segregation analysis were applied to confirm the findings. Results All four patients including 3 males and 1 female presented with excessive startle reflex, a cautious gait and recurrent falls. Moreover, startle episodes were dramatically improved with the treatment of clonazepam in all cases. Exome sequencing revealed 2 homozygous GLRA1 mutations in the patients. The mutation c.1286T>A p.I429N has been previously reported, while c.754delC p.L252* is novel. Conclusions HPX is a treatable disease, and clonazepam is the drug of choice. By studying and reviewing the disorder, we summarized the phenotype, expanded the genotype spectrum, and discussed the possible pathogenic mechanisms to enhance the understanding and recognition of the disease. Early awareness of the disease is crucial to the prompt and proper administration, as well as the genetic counseling.
GRAPHENE AS TUNABLE STATIONARY PHASE ADDITIVE FOR ENANTIOSEPARATION
FEI-YUE TU,LIN-YAN YU,JIN-GANG YU,XIAOQING CHEN,QIANG FU,FEI-PENG JIAO,ZHI-GUANG PENG,TING ZHANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2013 NANO Vol.8 No.6
Graphene-based biosensor and chiral sensor have made significant progress in recent years. Because of the similarity of the optical enantiomers, enantioseparation is perhaps the most subtle to achieve. Developing more effectively chiral separation techniques based on graphene is highly desirable. Herein, pristine graphene was prepared and then applicated to assist resolution of two racemic drugs of propranolol and ofloxacin using thin-layer chromatography (TLC). In comparison with TLC chiral separation by only using pure D-(-)-tartaric acid as a selector with relatively low degree of separation, a mixture of graphene and D-(-)-tartaric acid is more attractive, efficient and ready available. The high specific resolution ability for racemic compounds aided by graphene might allow its potential application in future chiral separation technologies.