Research Trends on Immune Mechanisms of Acupuncture: A Literature Review

Noh Joonyong,Lim Jinkang,Shin Jeong Cheol,Bang Sung-Pil,Noh Geunwoong,Yoon Jin-Sol,Seon Yun-Gwon,Song Siyoung,Kim Jae-Hong 대한침구의학회 2023 대한침구의학회지 Vol.40 No.4

Recently, acupuncture has demonstrated extraordinary clinical results in the treatment of several categories of health conditions worldwide. The mechanisms of action of acupuncture (including immune mechanisms) have been investigated by biomedical studies over the last few decades. The immune mechanisms of representative clinical conditions and their clinical effects were thoroughly assessed, with a comprehensive investigation into the mechanisms of action of acupuncture (including immune responses) in this study. Conditions such as stroke, migraine, depression, chronic fatigue syndrome, lower back pain, hypertension, irritable bowel syndrome, sepsis, and allergic diseases were meticulously examined. This in-depth analysis aims to ensure a foundational understanding of the immune mechanisms involved in acupuncture, thereby serving as an initial step toward integrating the impact of acupuncture on the immune system.

A Pilot Study of Interferon-γ-Induced Specific Oral Tolerance Induction (ISOTI) for Immunoglobulin E-Mediated Anaphylactic Food Allergy

Noh, Geunwoong,Lee, Sang-Sun Mary Ann Liebert 2009 Journal of interferon & cytokine research Vol.29 No.10

<P>Food-induced anaphylaxis is a life-threatening, IgE-mediated disease. No specific therapeutic recommendations, aside from the avoidance of offending foods, exist at this time. However, specific oral tolerance induction for food allergy has been investigated by several groups. In this study, specific oral tolerance induction was attempted using interferon-gamma (IFN-gamma) as an adjuvant for IgE-mediated anaphylactic food allergies. A total of 25 patients with IgE-mediated anaphylactic food allergy to milk, eggs, or wheat were selected. IFN-gamma-induced specific oral tolerance induction (ISOTI) was conducted on 10 patients, while five patients were only treated with food, five patients received only IFN-gamma therapy, and five patients did not receive any treatment. Tolerance for IgE-mediated anaphylactic food allergy was successfully induced in all patients (10/10) with ISOTI, while no patients acquired tolerance for allergenic foods in the control groups. Food-specific IgE levels were increased, and skin prick test reactions significantly decreased after the completion of ISOTI. IFN-gamma-induced specific oral tolerance induction (ISOTI) is a promisingly effective treatment for IgE-mediated anaphylactic food allergy. IFN-gamma may be an important cytokine in tolerance induction. Simultaneous allergen stimulation with nonspecific immunomodulation of IFN-gamma was essential for specific tolerance induction in IgE-mediated anaphylactic food allergy.</P>

The effects of elimination diet on nutritional status in subjects with atopic dermatitis

Jungyun Kim,Jaryoung Kwon,Geunwoong Noh,Sang Sun Lee 한국영양학회 2013 Nutrition Research and Practice Vol.7 No.6

A food allergy is an adverse health effect arising from a specific immune response that occurs reproducibly upon exposure to a given food. In those with food allergies that are thought to cause aggravation of eczema, food avoidance is important. The objective of this study was to research the nutritional status of patients with food allergies. A total of 225 subjects diagnosed with atopic dermatitis underwent a skin prick test as well as measurement of serum immunoglobulin E. Food challenge tests were conducted using seven food items: milk, eggs, wheat, soybeans, beef, pork, and chicken. At post-food challenge visits to the test clinic, participants completed a three-day dietary record, which included two week days and one weekend day, in order to evaluate energy intake and diet quality during the challenge. We analyzed nutrient intake based on differential food allergens. Subjects with a food allergy to milk showed lower intake of Ca, Zn, and vitamin B₂, and subjects with a food allergy to egg showed lower intake of vitamin A, B₁, B₂, niacin, and cholesterol. Subjects with a food allergy to wheat and soybean showed lower intake of Ca, P, Fe, K, Zn, vitamin B₂, vitamin B?, and niacin; and subjects with a food allergy to beef, pork, and chicken showed lower intake of Fe and higher intake of K, vitamin A, B₂. Subjects with atopic dermatitis were lacking in several nutrients, including vitamin A and vitamin C. A greater number of food allergies showed an association with a greater number of nutrient intake deficiencies. Allergen avoidance is the basic treatment for atopic dermatitis. However, when the allergen is food, excessive restriction can lead to nutrition deficiency. Findings of this study suggest the necessity for enhanced nutritional education in order to provide substitute foods for patients with food allergies who practice food restriction.

Terminology of Argentine Tango for Tango Therapy

Youngsoon Koh,Yoonchul Hur,Geunwoong Noh 한국탱고테라피학회 2019 J Tango Vol.1 No.2

Tango (Argentine tango) is applied clinically for therapeutic purposes. Not only does tango, as a kind of dance, involve complex whole body movements synchronized to music but tango movements seem to be complicated and have many unique postures. For the systemic application of tango therapy, the systemic analysis of tango movements and figures are absolutely necessary. For therapeutic purposes, tango therapy should be prescribed based on a common scientific description. To describe tango movements more scientifically and systemically, a uniform systematic standard terminology should be determined and defined. However, the determination and definition of the terminology for tango should be performed for the research of tango movements. In this article, the unique terminology of Argentine tango is listed and defined according to the original meaning in Spanish as the first step toward for the systemic standardization of tango

Tango Posture and Stance: Functional Anatomical Analysis and Therapeutic Characteristics

Youngsoon Koh,Yoonchul Hur,Geunwoong Noh 한국탱고테라피학회 2019 J Tango Vol.1 No.2

Argentine tango (tango) is used clinically for therapeutic purposes. However, tango can be applied just as a dance or as a kind of exercise. The analysis of the unique characteristics of tango stance and posture was analysed according to functional anatomy to obtain more effects by tango therapy. The study was conducted at Tango School (Tango Studio in Seoul, Korea), which is well equipped for tango lessons. Two tango masters and two tango experts (an expert in tango medicine and a medical doctor) participated in the precise analysis and description of tango posture and stance. General descriptions of tango posture were translated into a medical description. The results were obtained through the consensus of all participants. The upper body alignment for the tango posture and the standard methods of the tango stance were deduced. Thereafter, the tango posture was finally determined. In this article, an analysis of the unique characteristics of tango posture and stance is conducted, and the scientific rationale for why tango is beneficial for health even when only the tango posture and stance are used is suggested

IL-10 is Predominantly Produced by CD19(low)CD5(+) Regulatory B Cell Subpopulation: Characterisation of CD19 (high) and CD19(low) Subpopulations of CD5(+) B cells

Jae Ho Lee,Geunwoong Noh,노준용,최완수,이상선 연세대학교의과대학 2011 Yonsei medical journal Vol.52 No.5

IL-10 production by CD19(+)CD5(+) B cells was investigated, by determining the expression levels of CD19, a classical B cell marker. Peripheral mononuclear cells were stained with fluorescence-conjugated anti-CD5, anti-CD19, anti-IL-10, and Annexin V. Interestingly, IL-10-producing B cells were found to be localised within the CD19(low)CD5(+) B cell subset. Apoptotic changes were also observed mainly in CD19(low) cells among B cells. Thus, CD5(+) B cells should be classified as CD19(high) and CD19(low) cells, and the immunological significance of CD19 for the IL-10 production by CD5(+) B cells requires further studies.

Basic Tango Elements for Tango Therapy

Youngsoon Koh,Yoonchul Hur,Geunwoong Noh 한국탱고테라피학회 2019 J Tango Vol.1 No.2

Argentine tango (tango) is used clinically for therapeutic purposes. Effective tango therapy analyses tango’s unique characteristics according to functional anatomical kinematics for standard tango movements. Many kinds of movement exist in tango, from simple to complicated figures. This article systematically dissects and reviews tango elements that consist of complicated tango figures. One can question the movements from the terms that are used to teach tango movements in the lesson. The article evaluates the therapeutic application of tango elements such as posture and stance, tango gait as a linear movement, holding and tension, ocho, and dissociation as a round movement. It concludes that tango therapy can be performed using tango according to functional anatomical descriptions.

Tango Ocho - 1 : Functional Anatomical Characteristics of Dissociation and the Tango Pivot

Youngsoon Koh,Yoonchul Hu,Chang Won Ha,Geunwoong Noh 한국탱고테라피학회 2019 J Tango Vol.1 No.2

Argentine tango (tango) has been used in therapy in the medical field. Tango has many unique movements, and the basic elements of tango were recently analysed according to the kinematic description of tango terms. The functional anatomical significance and clinical application of tango postures and stances as well as tango gait define level 1-grade tango therapy. Tango ocho is classified as level 2-grade tango therapy and contains the distinctive motion of tango. Additionally, ocho is a way to move the free lower limb across the stance limb (the weight-supporting lower limb). An ocho pivot is unique to tango. The ocho pivot sequence (OPS) is the method for performing ocho step sequences, including ocho adelante, ocho atras and ocho cortado. The OPS consists of the following: 1st dissociation, torsion of the body (torsion), release of the torsion and 2nd dissociation. From the OPS, many artistic and characteristic motions of the tango are developed. In this article, an analysis of the unique characteristics of tango ocho was conducted, including a functional anatomical description for use in the therapeutic application of tango therapy..

Characterization of food allergies in patients with atopic dermatitis

Jaryoung Kwon,Jungyun Kim,Sunheui Cho,Geunwoong Noh,Sang Sun Lee 한국영양학회 2013 Nutrition Research and Practice Vol.7 No.2

We examined the characteristics of food allergy prevalence and suggested the basis of dietary guidelines for patients with food allergies and atopic dermatitis. A total of 2,417 patients were enrolled in this study. Each subject underwent a skin prick test as well as serum immunoglobulin E (IgE) measurement. A double-blind, placebo-controlled food challenge was conducted using milk, eggs, wheat, and soybeans, and an oral food challenge was performed using beef, pork, and chicken. Food allergy prevalence was found among 50.7% in patients with atopic dermatitis. Among patients with food allergies (n = 1,225), the prevalence of non-IgE-mediated food allergies, IgE-mediated food allergies, and mixed allergies was discovered in 94.9%, 2.2%, and 2.9% of the patients, respectively. Food allergy prevalence, according to food item, was as follows: eggs = 21.6%, milk = 20.9%, wheat = 11.8%, soybeans = 11.7%, chicken = 11.7%, pork = 8.9% and beef = 9.2%. The total number of reactions to different food items in each patient was also variable at 45.1%, 30.6%, 15.3%, 5.8%, 2.2%, and 1.0% for 1 to 6 reactions, respectively. The most commonly seen combination in patients with two food allergies was eggs and milk. The clinical severity of the reactions observed in the challenge test, in the order of most to least severe, were wheat, beef, soybeans, milk, pork, eggs, and chicken. The minimum and maximum onset times of food allergy reactions were 0.2-24 hrs for wheat, 0.5-48 hrs for beef, 1.0-24 hrs for soybeans, 0.7-24 hrs for milk, 3.0-24 hrs for pork, 0.01-72 hrs for eggs, and 3.0-72 hrs for chicken. In our study, we examined the characteristics of seven popular foods. It will be necessary, however, to study a broader range of foods for the establishment of a dietary guideline. Our results suggest that it may be helpful to identify food allergies in order to improve symptoms in patients with atopic dermatitis.

Tango Gait for Tango Therapy : Functional Anatomical Characteristics of Tango Gait (‘Tango Gaitology’)

Youngsoon Koh,Yoonchul Hur,Ic Soo Kim,Chang Won Ha,Geunwoong Noh 한국탱고테라피학회 2019 J Tango Vol.1 No.2

Argentine tango (tango) has been applied therapeutically in recent decades for neurologic diseases, including Parkinson’s disease. Recently, the basic terminology of tango was defined, and the most simple and basic tango elements were classified for therapeutic purposes. Subsequently, the tango stance and posture were analysed systemically according to their functional anatomical descriptions, and the characteristics of tango gait were thus ascertained. Analysis was performed in a well-equipped facility appropriate for tango lessons and with two qualified tango masters and two tango experts. The following aspects of the tango gait associated with the purpose of movement were characterized: the single-limb support and dual-limb support of body weight; the variability of direction of movement; the gait cycle in normal gait and the gait cycle unit in tango gait; the difference in the way of walking; the asymmetric shape of the Wt-gaining limb and Wt-losing limb; the vertical and side-to-side displacement of centre of mass (CoM); the step width; the active vs passive movements; the absence of hand swing and kick-off; the concurrence of the body axis, Wt axis and the vertical fixation of the body axis; the difference in the principle of step; the single-limb stance duration and dual-limb support duration; the variation in gait velocity; and the movement known as adorno. Tango therapy effects similar to the effects of running, squatting and climbing may be obtained, even at a safe, slow velocity. From a medical viewpoint, tango has therapeutic effects on the muscular strengthening of posture and gait. Consequently, the posture, gait, balancing, mobility, and the rigidity of the body are possibly improved. Tango therapy provides good modality in those patients whose mobility is not favourable, such as those with neurologic diseases, including Parkinson’s disease, and it can promote the health of older people. Additionally, tango possibly strengthens the core muscles and can be applied for urinary inconstancy. More investigation may be needed.