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Potential Role of Electrochemotherapy as Anticancer Treatment for Cutaneous and Subcutaneous Lesions
Zygogianni, Anna,Kyrgias, George,Scarlatos, John,Koukourakis, Michael,Souliotis, Kyriakos,Kouvaris, John,Kelekis, Nikolaos,Kouloulias, Vassilis Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.8
Background: The aim of this study was to investigate whether electrochemotherapy is a clinically and cost-effective treatment option against skin tumors. Materials and Methods: We performed an analysis of the current literature based on database searches in PubMed/MEDLINE and we included articles till July 2012. Terms used for the search were 'electrochemotherapy', 'skin cancer', 'recurrence', and 'cutaneous and subcutaneous tumors'. Only papers published in English were included. In addition, we performed an analysis of the cost effectiveness of the method. Results: The combination of physics and chemistry is the foundation for electrochemotherapy and its efficacy, independent of the tumor histology. Clinical data showed that ECT is well tolerated and can be used in difficult cases without other available treatment options. The analysis also showed that the treatment is feasible and cost-effective. Conclusions: Electrochemotherapy is a clinically efficient safe and cost-effective treatment and clinicians should not hesitate to use it as alternative therapeutic modality or as palliative treatment.
Male Breast Carcinoma: Epidemiology, Risk Factors and Current Therapeutic Approaches
Zygogianni, Anna G.,Kyrgias, George,Gennatas, Costantinos,Ilknur, Aytas,Armonis, Vassilios,Tolia, Maria,Papaloukas, Christos,Pistevou, Gompaki,Kouvaris, John,Kouloulias, Vassilios Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1
Male breast cancer is a very rare disease with an incidence of about 0.5-1% comparing with the one of female breast cancer but relatively little is known about its cause. Treatment strategies for breast cancer in males are derived from studies performed among females. The probable reasons behind the frequent, late diagnoses presented at stages III or IV might be the lack of awareness. The rarity of the disease precludes large prospective randomized clinical trials. This study reviews male breast cancer and its risk factors, recommendations for diagnosis and the management of patients with male breast cancer.
Kalogeridi, Maria-Aggeliki,Kouloulias, Vassilios,Zygogianni, Anna,Kyrgias, George The Korean Society for Radiation Oncology 2014 Radiation Oncology Journal Vol.32 No.2
We present a case of unresectable cancer of the base of tongue treated with hypofractionated 3D conformal radiotherapy and concomitant chemotherapy. Based on the excellent tumour response in this radiotherapy regimen and international experience in short course treatments we shortly reviewed, we propose that this therapeutic approach could be considered in a curative setting for patients unsuitable for the a standard long course radiochemotherapy schedule.
Maria-Aggeliki Kalogeridi,MD,PhD,Vassilios Kouloulias,MD,PhD,Anna Zygogianni,MD,PhD,George Kyrgias,MD,PhD 대한방사선종양학회 2014 Radiation Oncology Journal Vol.32 No.2
We present a case of unresectable cancer of the base of tongue treated with hypofractionated 3D conformal radiotherapy and concomitant chemotherapy. Based on the excellent tumour response in this radiotherapy regimen and international experience in short course treatments we shortly reviewed, we propose that this therapeutic approach could be considered in a curative setting for patients unsuitable for the a standard long course radiochemotherapy schedule.