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Immunoglobulin G<sub>4</sub>-related sclerosing cholangitis
( George Goodchild ),( Stephen P. Pereira ),( George Webster ) 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.5
Immunoglobulin G<sub>4</sub>-related disease (IgG<sub>4</sub>-RD) is a systemic fibroinflammatory condition of which Ig<sub>G</sub>4-related sclerosing cholangitis (IgG<sub>4</sub>-SC) is the biliary manifestation. In this review, we provide an overview of IgG<sub>4</sub>-RD, with a focus on the biliary manifestations. In particular, we describe the important differential diagnoses of IgG<sub>4</sub>-SC, namely, primary sclerosing cholangitis and cholangio-carcinoma, outline diagnostic criteria for IgG<sub>4</sub>-SC, provide insight into possible pathophysiological mechanisms underlying the disease and discuss short and long-term management options of this recently described disease.
Immunoglobulin G4-related sclerosing cholangitis
George Goodchild,Stephen P. Pereira,George Webster 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.5
Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition of which IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation. In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the important differential diagnoses of IgG4-SC, namely, primary sclerosing cholangitis and cholangiocarcinoma, outline diagnostic criteria for IgG4-SC, provide insight into possible pathophysiological mechanisms underlying the disease and discuss short and long-term management options of this recently described disease.