Some fixed point theorems for modified JS-G-contractions and an application to integral equations

V. Srinivas Chary,G. Sudhaamsh Mohan Reddy,Huseyin Isik,Hassen Aydi,D. Srinivasa Chary,Stojan Radenovic 한국전산응용수학회 2020 Journal of applied mathematics & informatics Vol.38 No.5

In this article, we establish some fixed point results in G-metric spaces using the modified JS-G-contractions and we provide some suitable examples to support the results. Also, we give an application to solve an integral equation.

Toxic chrome removal from industrial effluents using marine algae: Modeling and optimization

A. Nagababu,D. Srinivasa Reddy,G.V. Krishna Mohan 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.114 No.-

Chromium is a toxic heavy metal with a high recalcitrant and carcinogenic nature even at very low concentrations. In the current investigation, systems thinking analysis is adopted to understand the deleteriouseffects of chromium on the environment. Hazardous chromate ions are effectively been remediatedfrom industrial discharges by employing the robust adsorbent prepared from marine algae, GracilariaRhodophyta Biochar. The combined effect of physicochemical factors such as contact time, pH, biochardosage and initial chromate concentration on adsorption performance is analyzed by adopting the statisticalResponse Surface Methodology. At the optimum operating conditions of pH: 2–4; GRB dosage:0.3 g/100 mL; contact time: 90 min; initial chromate concentration: 60 mg/L and temperature:30 C ± 2, an amount of 19.6 mg/g of chromate ions are removed by the developed adsorbent. The characterizationresults showcased the efficiency of biochar towards the adsorption of chromate ions fromwastewater. The adsorption phenomenon follows the Langmuir isotherm model and pseudo-secondorderrate kinetics. The investigation of selectivity reveals that the developed adsorbent has a good selectivityfor Cr(VI) even with the presence of competing ions in the same medium. The developed robusttechnology can be successfully applied for the adsorption of toxic chromate ions from contaminatedindustrial samples.

An efficient and green synthesis of benzo[4,5]imidazo[1,2-a]pyrimidines using highly active and stable poly acrylic acid-supported layered double hydroxides

Veeranarayana Reddy, M.,Chandra Sekhar Reddy, G.,Thi Kim Lien, N.,Kim, D.W.,Jeong, Y.T. Pergamon Press 2017 Tetrahedron Vol.73 No.10

A facile and efficient method for the synthesis of benzo[4,5]imidazo[1,2-a]pyrimidines has been achieved via highly active and reusable heterogeneous poly acrylic acid-supported layered double hydroxides (PAA-g-LDHs) catalyst promoted one-pot reaction of 1H-benzo[d]imidazol-2-amine, with α,β-unsaturated carbonyl compounds under solvent-free conditions. PAA-g-LDHs catalyst was successfully synthesized via reversible addition-fragmentation chain-transfer polymerization using grafting reaction and was characterized by different analytical techniques. The significant features of this reaction include expedient one-pot process, short reaction time, excellent yields, wide substrate scope and operational simplicity. Also, the catalyst could be reused for several consecutive runs without any apparent loss in its catalytic activity.

Extrusion Processing of Low-Inhibitor Soybeans Improves Growth Performance of Early-Weaned Pigs

Kim, I.H.,Hancock, J.D.,Jones, D.B.,Reddy, P.G. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.8

Two experiments were conducted to determine the effects of roasting and extrusion on nutritional value of conventional and low-inhibitor soy beans for nurser-age pigs. In Exp. 1, 100 weaning pigs (7.5 kg average initial BW) were used in a 35-d growth assay to determine the effects of processing method (roasting in a Rast-A-Tron$^{TM}$ raster vs extrusion in an Insta-Pro$^{TM}$ extruder) on the nutritional value of Williams 82 soybeans with (+K) and without (-K) gene expression for the Kunitz trypsin inhibitor. Treatments were 48% soybean meal with added soybean oil, +K roasted, +K extruded, -K roasted and -K extruded. All diets were formulated to contain 3.5 Mcal DE/kg, with 0.92% lysine for d 0 to 14 and 0.76% lysine for d 14 to 35 of the experiment. The lysine concentrations were 80% of NRC (1988) recommendations to accentuate difference in response to protein quality and lysine availability. For d 0 to 14, pigs fed extruded soybeans (+K and -K) had greater ADG (p<0.001), ADFI (p<0.09) and gain/feed (p<0.01) than pigs fed roasted soybeans. For d 14 to 35 and overall, the same effects were noted, i.e., pigs fed extruded soybeans had greater ADG, ADFI and gain/feed than pigs fed roasted soybeans (p<0.03). Also, pigs fed -K soybeans were more efficient (p<0.008) than pigs fed +K soybeans. In Exp. 2, 150 weanling pigs (7.0 kg average initial BW) were used in a 35-d growth assay. All diets were formulated to contain 3.5 Mcal DE/kg, with 1.25% lysine for d 0 to 14 and 1.10% lysine for d 14 to 35 of the experiment. The lysine concentrations were formulated to be in excess of NRC recommendation to determine if differences in nutritional value of the soybean preparations could be detected in protein-adequate diets. For d 0 to 14 (p<0.06), 14 to 35 (p<0.03) and 0 to 35 (p<0.02), pigs fed extruded soybeans had greater ADG and gain/feed than pigs fed roasted soybeans. Apparent digestibilities of DM, N and GE were greater for diets with extruded soybeans than diets with roasted soybeans and diets with soybean meal and soybean oil were intermediate. The response to extrusion processing was greater with -K than +K soybeans, with pigs fed extruded -K soybeans having the greatest growth performance and nutrient digestibilities and lowest skin-fold thickness of any treatment. In conclusion, extrusion yielded a full-fat soy product of greater nutritional value than roasting. Also, selection against genetic expression of the Kunitz trypsin inhibitor improved nutritional value of the resulting soybean preparations.

An efficient and green synthesis of highly functionalized N-methyl-2-nitro-aryl-1H-benzo[f]chromen-3-amine derivatives under catalyst-free conditions

Reddy, M.V.,Reddy, G.D.,Kim, J.T.,Jeong, Y.T. Pergamon Press 2016 Tetrahedron Vol.72 No.41

<P>A highly efficient and environmentally benign protocol has been developed for the construction of various potentially biologically active N-methyl-2-nitro-aryl-1H-benzo[f]chromen-3-amine derivatives using one-pot, multi-component cascade reaction of various naphthalen-2-ol, aldehydes, and (E)-N-methyl-1-(methylthio)-2-nitroethenamine under catalyst-free conditions in the presence of green solvent medium (ethanol water) is described. The significant features of this protocol are short reaction times, provide excellent yields, avoidance of toxic solvents and catalysts, no column chromatographic purification, atom-economy and uses ethanol water as a green solvent which is considered to be relatively environmentally benign. This is the first example of the condensation of naphthalen-2-ol, aldehydes, and (E)-N-methyl-1-(methylthio)-2-nitroethenamine to provide a novel series of 1H-benzo[f]chromen-3-arnine derivatives. (C) 2016 Elsevier'Ltd. All rights reserved.</P>

Extracranial systemic antitumor response through the abscopal effect induced by brain radiation in a patient with metastatic melanoma

D'Andrea, Mark A.,Reddy, G.K. The Korean Society for Radiation Oncology 2019 Radiation Oncology Journal Vol.37 No.4

The abscopal effect is a term that has been used to describe the phenomenon in which localized radiation therapy treatment of a tumor lesion triggers a spontaneous regression of metastatic lesion(s) at a non-irradiated distant site(s). Radiation therapy induced abscopal effects are believed to be mediated by activation and stimulation of the immune system. However, due to the brain's distinctive immune microenvironment, extracranial abscopal responses following cranial radiation therapy have rarely been reported. In this report, we describe the case of 42-year-old female patient with metastatic melanoma who experienced an abscopal response following her cranial radiation therapy for her brain metastasis. The patient initially presented with a stage III melanoma of the right upper skin of her back. Approximately 5 years after her diagnosis, the patient developed a large metastatic lesion in her upper right pectoral region of her chest wall and axilla. Since the patient's tumor was positive for BRAF and MEK, targeted therapy with dabrafenib and trametinib was initiated. However, the patient experienced central nervous system (CNS) symptoms of headache and disequilibrium and developed brain metastases prior to the start of targeted therapy. The patient received radiation therapy to a dose of 30 Gy delivered in 15 fractions to her brain lesions while the patient was on dabrafenib and trametinib therapy. The patient's CNS metastases improved significantly within weeks of her therapy. The patient's non-irradiated large extracranial chest mass and axilla mass also shrank substantially demonstrating the abscopal effect during her CNS radiation therapy. Following radiation therapy of her residual chest lesions, the patient was disease free clinically and her CNS lesions had regressed. However, when the radiation therapy ended and the patient continued her targeted therapy alone, recurrence outside of her previously treated fields was noted. The disease recurrence could be due to the possibility of developing BRAF resistance clones to the BRAF targeted therapy. The patient died eventually due to wide spread systemic disease recurrence despite targeted therapy.

Role of molybdenum trioxide in enhancing the humidity sensing performance of magnesium ferrite/molybdenum trioxide composite

Babu Reddy, L.P.,Megha, R.,Chethan, B.,Raj Prakash, H.G.,Ravikiran, Y.T.,Ramana, C.H.V.V.,Kim, D. ELSEVIER 2018 INORGANIC CHEMISTRY COMMUNICATIONS Vol.98 No.-

<P><B>Abstract</B></P> <P>In the present work, we prepared magnesium ferrite/molybdenum trioxide (MFMO) nanocomposite using mechano chemical mixing method for humidity sensor at room temperature. Enhancement in active sites for water adsorption in the composite due to the presence of MoO<SUB>3</SUB> confirmed from X-ray diffraction (XRD) studies. Change in grain size distribution and increase in intergranular pores in the composite favouring water adsorption confirmed from its scanning electron microscopy (SEM) image. Increased agglomeration of nano sized particles and improved crystallinity of the composite confirmed from Transmission electron microscopy (TEM) studies and selected area electron diffraction (SAED) pattern. The composite showed maximum sensing response of 4902 as against 183 of MF in the range 11%–97% RH. The response and recovery times of the composite were found to be 45 s and 74 s respectively while those of MF 225 s and 364 s respectively. The nanocomposite sample showed stable humidity sensing ability and a low humidity hysteresis. Molybdenum trioxide plays a major role in enhancing the humidity sensing performance of MFMO composite at room temperature. The sensing mechanism discussed on the basis of chemisorptions, physisorption and capillary condensation processes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Humidity sensing response of magnisium ferrite (MF) and magnesium ferrite-molybdenum trioxide (MFMO) composite presented. </LI> <LI> The MFMO showed maximum sensing response of 4902 as against 183 of MF in the range 11%-97% RH. </LI> <LI> The response and recovery times of the composite were found to be 45 s and 74 s respectively. </LI> <LI> The sensing mechanism MFMO discussed on the basis of chemisorptions, physisorption and capillary condensation processes. </LI> </UL> </P>

Transcription factors controlling the expression of oxidative stress associated genes in rice (Oryza sativa L.)

Sujitha D.,Kumar H. G. Jalendra,Thapliayal Garima,Pal Garima,Vanitha P. A.,Uttarkar Akshay,Patil Mahesh,Reddy B. H. Rajashekar,Niranjan Vidya,Rayalcheruvu Usha,Govind Geetha,Udayakumar M.,Vemanna Ramu 한국식물생명공학회 2023 Plant biotechnology reports Vol.17 No.6

Reactive oxygen species (ROS) increases under stress and damages cellular processes leading to decrease in productivity. Many genes have been known to be involved in scavenging ROS. We report the identification of master regulators of oxidative stress responsive genes from contrasting rice genotypes. Using microarray analysis, we identified 52 differentially expressed transcription factors (TFs) from the contrasting rice genotypes under oxidative stress. Upregulation of these TFs induces the expression of many genes in resistant or sensitive genotypes. The promoters of these TFs are enriched with reactive oxygen species binding elements (ROSE). The promoter analysis of genes that respond to oxidative stress also revealed that these TF binding sites were present and that these genes expressed differently in contrasting rice genotypes. The transcript levels of TFs correlate with expression level of stress responsive genes coding for various pathways such as polyol, ABA, JA biosynthesis and signaling. Functional validation of HSF-C1a using virus-induced gene silencing (VIGS), showed reduced expression of its target genes. Our study demonstrates that identified TFs could act as major transcriptional regulators of oxidative stress tolerance. These TFs can be used as markers and are potential candidates to improve stress tolerance in plants.

INFLUENCE OF HALL CURRENT AND HEAT SOURCE ON MHD FLOW OF A ROTATING FLUID IN A PARALLEL POROUS PLATE CHANNEL

M. VENKATESWARLU,G. UPENDER REDDY,D. VENKATA LAKSHMI 한국산업응용수학회 2018 Journal of the Korean Society for Industrial and A Vol.22 No.4

This paper examined the MHD and thermal behavior of unsteady mixed convection flow of a rotating fluid in a porous parallel plate channel in the presence of Hall current and heat source. The exact solutions of the concentration, energy and momentum equations are obtained. The influence of each governing parameter on non dimensional velocity, temperature, concentration, skin friction coefficient, rate of heat transfer and rate of mass transfer at the porous parallel plate channel surfaces is discussed. During the course of numerical computation, it is observed that as Hall current parameter and Soret number at the porous channel surfaces increases, the primary and secondary velocity profiles are increases while the primary andsecondaryskinfrictioncoefficientsareincreasesatthecoldwallanddecreasesattheheated wall. In particular, it is noticed that a reverse trend in case of heat source parameter

Modelling and experimental investigations on stepped beam with cavity for energy harvesting

A. Rami Reddy,M. Umapathy,D. Ezhilarasi,G. Uma 국제구조공학회 2015 Smart Structures and Systems, An International Jou Vol.16 No.4

This paper presents techniques to harvest higher voltage from piezoelectric cantilever energy harvester by structural alteration. Three different energy harvesting structures are considered namely, stepped cantilever beam, stepped cantilever beam with rectangular and trapezoidal cavity. The analytical model of three energy harvesting structures are developed using Euler-Bernoulli beam theory. The thickness, position of the rectangular cavity and the taper angle of the trapezoidal cavity is found to shift the neutral axis away from the surface of the piezoelectric element which in turn increases the generated voltage. The performance of the energy harvesters is evaluated experimentally and is compared with regular piezoelectric cantilever energy harvester. The analytical and experimental investigations reveal that, the proposed energy harvesting structures generate higher output voltage as compared to the regular piezoelectric cantilever energy harvesting structure. This work suggests that through simple structural modifications higher energy can be harvested from the widely reported piezoelectric cantilever energy harvester.