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RISS 인기검색어
- 검색키워드
- 저자 : Filiz Koseoglu (검색결과 3 건)
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Ahmet Goktug Ertem,Filiz Ozcelik,Haci Ahmet Kasapkara,Cemal Koseoglu,Serdal Bastug,Huseyin Ayhan,Cenk Sari,Nihal Akar Bayram,Emine Bilen,Tahir Durmaz,Telat Keles,Engin Bozkurt 대한심장학회 2016 Korean Circulation Journal Vol.46 No.6
Background and Objectives: In this study, we examined the role of inflammatory parameters in an apical mural thrombus with a reduced ejection fraction due to large anterior myocardial infarction (MI). Subjects and Methods: A total of 103 patients who had suffered from heart failure, 45 of whom had left ventricular apical thrombus (AT) after a large anterior MI, were enrolled in the study. A detailed clinical history was taken of each participant, biochemical inflammatory markers, which were obtained during admission, were analyzed and an echocardiographical and angiographical evaluation of specific parameters were performed. Results: There were no statistically significant differences in terms of age, gender, and history of hypertension, diabetes mellitus, and atrial fibrillation between both groups (p>0.05). Similarly there were no statistically significant differences in terms of biochemical and echocardiographic parameters (p>0.05). However, there were significant differences in terms of neutrophil lymphocyte ratio (p=0.032). After a multivariate regression analysis, neutrophil lymphocyte ratio (NLR) was an independent predictor of thrombus formation (ß: 0.296, p=0.024). The NLR >2.74 had a 78% sensivity and 61% specifity in predicting thrombus in patients with a low left ventricular ejection fraction. Conclusion: In this study, neutrophil lymphocyte ratios were significantly higher in patients with apical thrombus.
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Neutrophils Are Decreased in Obsessive-Compulsive Disorder: Preliminary Investigation
Murad Atmaca,Faruk Kilic,Filiz Koseoglu,Bilal Ustundag 대한신경정신의학회 2011 PSYCHIATRY INVESTIGATION Vol.8 No.4
Objective There has been no study in the literature evaluating total blood count in obsessive-compulsive disorder (OCD). Therefore,we performed the present study to spesifically measure serum total blood count particularly white blood cells to see whether or not its eventual alterations might have an etiopathogenetic significance in patients with OCD. Methods Total blood count was measured in thirty patients and same number of healthy controls. Additionally, all patients were assessed by Yale-Brown Obsession Compulsion Scale (Y-BOCS). Results Except for neutrophil count, there were no significant differences between the groups regarding any haematological parameter. The mean neutrophil count of the patient group was lower compared to that of the control subjects. Conclusion In conclusion, the present study suggests that neutrophil count is reduced in pure OCD patients and this finding may contribute to the role of immunological factors in the pathogenesis of OCD.
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Hippocampal Neurochemical Pathology in Patients with Panic Disorder
Murad Atmaca,Hanefi Yildirim,M. Gurkan Gurok,Muammer Akyol,Filiz Koseoglu 대한신경정신의학회 2012 PSYCHIATRY INVESTIGATION Vol.9 No.2
Objective In the present study, we measured hippocampal N-acetyl-l-aspartate (NAA), choline (CHO) and creatine (CRE) values in patients with panic disorder and healthy control subjects using in vivo 1H MRS. Methods We scanned 20 patients meeting Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) criteria for panic disorder and 20 matched healthy controls with a 1.5 Tesla GE Signa Imaging System and measured of NAA, CHO, and CRE in hippocampal regions. ResultsaaWhen NAA, CHO and CRE values were compared between groups, statistically significant lower levels for all ones were detected for both sides. Conclusion Consequently, in the present study we found that NAA, CHO and CRE values of the patients with panic disorder were lower than those healthy controls. Future studies involving a large number of panic patients may shed further light on the generalizability of the current findings to persons with panic disorder. Objective In the present study, we measured hippocampal N-acetyl-l-aspartate (NAA), choline (CHO) and creatine (CRE) values in patients with panic disorder and healthy control subjects using in vivo 1H MRS. Methods We scanned 20 patients meeting Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) criteria for panic disorder and 20 matched healthy controls with a 1.5 Tesla GE Signa Imaging System and measured of NAA, CHO, and CRE in hippocampal regions. ResultsaaWhen NAA, CHO and CRE values were compared between groups, statistically significant lower levels for all ones were detected for both sides. Conclusion Consequently, in the present study we found that NAA, CHO and CRE values of the patients with panic disorder were lower than those healthy controls. Future studies involving a large number of panic patients may shed further light on the generalizability of the current findings to persons with panic disorder.
KCI
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