http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
피질하혈관성 치매와 알쯔하이머병에서 뇌량 용적의 변화 비교
이애영,손은희,유성동 대한치매학회 2002 Dementia and Neurocognitive Disorders Vol.1 No.2
Background : The clinical significance of callosal atrophy in demented patients has not been elucidated. We performed this study to compare the total and regional difference of corpus callosum according to demenua subtypes and analyzed the relationship with the white matter changes. Methods : Twenty-eight patients with Alzheimer's disease (NINCDS-ADRDA criteria), 17 patients with vascular dementia (NINDS-AIREN criteria), and 14 healthy controls were included. The total area of corpus callosum and three distinct subdivision were measured by manual tracing with Paintshop Pro 6.02 software. The degree of white matter changes were graded by the Scheltens' scale. The MMSE and Modified Mini-Mental Stats (3MS) Examination were used for cognitive function test Results : Total callosal area was much smaller in vascular dementia compared with those of Alzheimer's disease and control. The degree of white matter change correlated siginficantiy with the callosal atrophy in vascular dementia Callosal atrophy was proportional to the cognitive decline. Conclusion : We suggest that callosal atrophy in patients with subcortical vascular dementia may be a neuroradiological clue for the coginitive decline and reflects the cerebral white matter injury.
유주영;김미애;박은옥;박유미;최주영;최은정;김명주 서울여자대학교 컴퓨터과학연구소 2004 정보기술논문지 Vol.2 No.-
악성코드에 대한 보다 바람직한 예방은 클라이언트측이 아닌 서버측에서 이루어지는 것이다. 본 논문에서는 새로운 개념 의 서버용 안티바이러스 엔진인 SAVE 1.0을 설계 구현하여 제시한다. SAVE는 기본적으로 1개의 AV모니터와 다수의 AV에이전트로 구성되어 있는데 다중 CPU를 장착한 병렬처리서버의 특징을 직접 활용하기 위하여 관리자가 다중쓰레드 기법을 직접 지정할 수 있도록 하고 있다 악성코드를 5가지 부류로 구분하여 바이러스 시그너쳐 DB를 구축 제공함으로써 부류별 진단을 지정할 수 있도록 하고 있으며 실시간 네트워크 패킷 검사를 통한 악성코드 유입 점검 기능도 제공한다. 웹 기반의 관리자 인터페이스는 뛰어난 사용자 편의성을 제공하고 있다. 성능실험결과 악성코드 검색율은 국내외 상용제품과 비교해서 매우 우수한 것으로 나타났으며 검색속도에 있어서도 서버의 CPU 수 증가에 거의 선형 비례하여 향상되는 특징을 보이고 있다. It is more desirable to prevent and detect the malicious codes in server system rather than in client PCs. In this paper, we suggest a new anti-virus engine, SAVE 1.0, which is executed on a parallel processing server. SAVE consists of 1 AV monitor and several AV agents. A system administrator can control the degree of multi-thread directly in order to enhance the utilization of parallel processing servers. Virus signature DBs in SAVE are classified into 5 categories, which support system administrator's options to use the classifier or not. By real-time checking of network packets, the influx of malicious codes can be prevented. Web-based GUI is one of the convenient functions provided in SAVE. In performance tests, we have confirmed that SAVE has higher virus detection ratio than any other AV engine, and SAVE has a desirable feature as an software of parallel processing servers since the performance of SAVE is improved almost linearly as the CPUs in a parallel processing server increases.
Ju-Eun Park,Kyeong-Sook Choi,Yu-Ri Han,Jeong-Eun Kim,Jay Song,Je-Chun Yu,Ji-Ae Yun 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.8
Objective Written exposure therapy (WET) is exposure therapy for post-traumatic stress disorder (PTSD). Compared to evidencebased treatments for PTSD, WET requires only five sessions, has a shorter session time, and no between-session assignments. The current study examined the efficacy of WET among Korean patients with PTSD due to various traumatic events on PTSD symptoms, depressive symptoms, and global functioning levels. Methods The study recruited 41 patients with a current primary diagnosis of PTSD in psychiatric outpatient clinics. Assessments were conducted at baseline, and at 6, 12, and 24 weeks following the first treatment session. Results In total, 25 patients started WET. Findings showed a significant reduction in the rate of PTSD diagnosis and symptom severity scores. Fourteen of 23 (60.9%) patients at 6 weeks, 15 of 22 (68.2%) patients at 12 weeks, and 14 of 18 (77.8%) patients at 24 weeks no longer met the diagnosis of PTSD. Depressive symptoms and global function scores also improved after WET. The dropout rate was 8% (n=2). Conclusion This study suggests the feasibility of implementing WET among various types of patients with PTSD in Korea and other Asian countries.
Yu, Hyun-Ju,Shin, Ji-Ae,Yang, In-Hyoung,Won, Dong-Hoon,Ahn, Chi Hyun,Kwon, Hye-Jeong,Lee, Jeong-Sang,Cho, Nam-Pyo,Kim, Eun-Cheol,Yoon, Hye-Jung,Lee, Jae Il,Hong, Seong-Doo,Cho, Sung-Dae Elsevier 2017 Archives of oral biology Vol.84 No.-
<P><B>Abstract</B></P> <P><B>Objective</B></P> <P>Caffeic acid phenethyl ester (CAPE), a natural honeybee product exhibits a spectrum of biological activities including antimicrobial, anti-inflammatory, antioxidant and antitumor actions. The purpose of this research was to investigate the anticancer potential of CAPE and its molecular mechanism in human oral cancer cell lines (YD15, HSC-4 and HN22 cells).</P> <P><B>Design</B></P> <P>To determine the apoptotic activity of CAPE and identify its molecular targets, trypan blue exclusion assay, soft agar assay, Western blot analysis, DAPI staining, and live/dead assay were performed.</P> <P><B>Results</B></P> <P>CAPE significantly suppressed transformation of neoplastic cells induced by epidermal growth factor (EGF) and 12-O-tetradecanoylphorbol 13-acetate (TPA) without inhibiting growth. CAPE treatment inhibited cell growth, increased the cleavages of caspase-3 and poly (ADP-ribose) polymerase (PARP), and augmented the number of fragmented nuclei in human oral cancer cell lines. CAPE activated Bax protein causing it to undergo a conformational change, translocate to the mitochondrial outer membrane, and oligomere. CAPE also significantly increased Puma expression and interestingly Puma and Bax were co-localized.</P> <P><B>Conclusion</B></P> <P>Overall, these results suggest that CAPE is a potent apoptosis-inducing agent in human oral cancer cell lines. Its action is accompanied by up-regulation of Bax and Puma proteins.</P> <P><B>Highlights</B></P> <P> <UL> <LI> CAPE suppresses neoplastic cell transformation induced by EGF and TPA. </LI> <LI> CAPE has apoptotic effect via Puma and Bax activation in oral cancer. </LI> <LI> Possibility of CAPE as potent apoptosis-inducing agent in oral cancer is proposed. </LI> </UL> </P>
임상실습에 대한 간호사와 간호학생의 교수효율성 인지정도
유필숙,김은실,김혜경,이성희,형희경,엄애용,김희선 대한간호행정학회 2008 간호행정학회지 Vol.14 No.3
Purpose: This study was conducted to use as a preliminary data to improve the quality of clinical nursing education by comparing the perception of teaching effectiveness in nurses and nursing students. Method: The participants were 165 nurses and 289 nursing students. Data was collected from June 2 to 16, 2008. The research instruments used an effective clinical instructors which was developed by Reeve(1994). Result: The perception of teaching effectiveness in nurses and nursing students were 3.45 and 3.19 respectively and it showed that nurses' perception of teaching effectiveness are higher than that of nursing students. Nurses had strong points in the factors of 「interpersonal relationship/ communication」, 「availability as a supporter」, 「teaching method and evaluation」. In additions, the teaching effectiveness had significant differences to age, years of work, position, educational background and job satisfaction in nurses, otherwise, sex, differences of educational level, satisfaction of clinical practicum and major in students. Conclusion: It is needed a further study as below: to develop an education system which is to improve an interpersonal relationship and to upgrade the quality of educator; to develop a teaching method program of clinical nursing education to improve teaching effectiveness.