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Eswaran, M.,Goyal, P.,Reddy, G.R.,Singh, R.K.,Vaze, K.K. Techno-Press 2013 Ocean systems engineering Vol.3 No.3
The main objective of this work is to investigate the sloshing behavior in a baffled and unbaffled three dimensional annular-sectored water pool (i.e., tank) which is located at dome region of the primary containment. Initially two case studies were performed for validation. In these case studies, the theoretical and experimental results were compared with numerical results and good agreement was found. After the validation of present numerical procedure, an annular-sectored water pool has been taken for numerical investigation. One sector is taken for analysis from the eight sectored water pool. The free surface is captured by Volume of Fluid (VOF) technique and the fluid portion is solved by finite volume method while the structure portions are solved by finite element approach. Baffled and un-baffled cases were compared to show the reduction in wave height under excitation. The complex mechanical interaction between the fluid and pool wall deformation is simulated using a partitioned strong fluid-structure coupling.
Sloshing of liquids in partially filled tanks - a review of experimental investigations
Eswaran, M.,Saha, Ujjwal K. Techno-Press 2011 Ocean systems engineering Vol.1 No.2
Liquid sloshing constitutes a broad class of problems of great practical importance with regard to the safety of liquid transportation systems, such as tank trucks on highways, liquid tank carriages on rail roads, ocean going vessels and propellant tanks in liquid rocket engines. The present work attempts to give a review of some selected experimental investigations carried out during the last couple of decades. This paper highlights the various parameters attributed to the cause of sloshing followed by effects of baffles, tank inclination, magnetic field, tuned liquid dampers, electric field etc. Further, recent developments in the study of sloshing in micro and zero gravity fields have also been reported. In view of this, fifteen research articles have been carefully chosen, and the work reported therein has been addressed and discussed. The key issues and findings have been compared, tabulated and summarized.
Eswaran, M.,Reddy, G.R. Techno-Press 2016 Wind and Structures, An International Journal (WAS Vol.23 No.5
Wind-induced and earthquake-induced excitations on tall structures can be effectively controlled by Tuned Liquid Damper (TLD). This work presents a numerical simulation procedure to study the performance of tuned liquid tank- structure system through ${\sigma}$-transformation based fluid-structure coupled solver. For this, a 'C' based computational code is developed. Structural equations are coupled with fluid equations in order to achieve the transfer of sloshing forces to structure for damping. Structural equations are solved by fourth order Runge-Kutta method while fluid equations are solved using finite difference based sigma transformed algorithm. Code is validated with previously published results. The minimum displacement of structure is observed when the resonance condition of the coupled system is satisfied through proper tuning of TLD. Since real-time excitations are random in nature, the performance study of TLD under random excitation is also carried out in which the Bretschneider spectrum is used to generate the random input wave.
Eswaran Kamaraj,박상혁 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
We report a series of imidazole based fluorescent dyes and their photophysical properties in particularly ESIPT. The impact of structural variation on photophysical properties and their association with solvent’s polarity and proticity were throughly investigated by comparing with their analogues of blocked ESIPT functionality. We have investigated their photophysical properties, using experimental transient absorption and theoretical DFT/TDDFT. Besides, the urease inhibitory activity of these compounds against Jack bean urease was also studied. All but one of the obtained compounds displayed inhibitory potential, as demonstrated by highest inhibition activity (0.0288±0.0034). Docking stimulation was performed to into the crystal structure of Jack bean urease and caprin protein at the active site to the probable binding mode. Furthermore, anti-cancer activity of imidazole derivatives were peformed by MTT analysis towards stomach cancer cell lines (AGS).
Development of ethosome comprising combined herbal extracts and its effect on hair growth
Madhunithya Eswaran,Venkatesh Gunasekaran,Shyamala Govindarajan,Manjari Venkatraman,Ramesh Santhanam,Karuppaiah Arjunan,Sankar Veintramuthu 경희대학교 융합한의과학연구소 2021 Oriental Pharmacy and Experimental Medicine Vol.21 No.1
The petroleum ether (pet. ether) and ethanol extracts of leaves of Phyllanthus niruri (P. niruri), rhizomes of Zingiber officia-nale (Z. officianale) and Croton tiglium Linné (C. tiglium Linné) seeds were prepared and loaded in ethosomal formulations to evaluate the hair growth promoting activity along with safety. Phytochemical constituents in the extracts were determined. The heavy metal analysis, sterility tests for extracts, and high-performance thin layer chromatography (HPTLC) analysis of the petroleum ether, ethanol extracts, and formulations were carried out. HPTLC analysis confirmed prepared extracts and formulations contain flavonoids and phenols. The in-vitro evaluation of keratinocytes cell line studies with combined pet. ether extract formulation shows high cytotoxic activity IC50 43 μg/mL. The hair follicular density, A/T ratio, and number of hair follicles are more in pet. ether extract of C. tigilum loaded ethosome formulation and combined pet. ether extract loaded ethosome formulation when compared to combined ethanol extract loaded ethosome formulation. Also, the combined ethanol extract loaded ethosome formulation showed more safety in topical application. Skin irritation studies showed no observed redness in combined ethanolic extract containing ethosome formulation. Histopathology report states that normal epidermis along with hair follicles and root of hair shaft on 21st day in combined extract containing ethosome formulation. Better outcome and safety were observed in the combined ethanolic extract of ethosomal formulations. The combined ethanol extracts loaded ethosome formulation was found to produce less cytotoxicity than combined pet. ether formulation and C. tiglium pet. ether extract loaded ethosome formulation