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        Pigment-Cellulose Nanofibril Composite and Its Application as a Separator-Substrate in Printed Supercapacitors

        Katariina Torvinen,Suvi Lehtimäki,Janne T. Keränen,Jenni Sievänen,Jari Vartiainen,Erkki Hellén,Donald Lupo,Sampo Tuukkanen 대한금속·재료학회 2015 ELECTRONIC MATERIALS LETTERS Vol.11 No.6

        Pigment-cellulose nanofibril (PCN) composites were manufactured in a pilot line and used as a separator-substrate in printed graphene and carbon nanotube supercapacitors. The composites consisted typically of 80% pigment and 20% cellulose nanofibrils (CNF). This composition makes them a cost-effective alternative as a substrate for printed electronics at high temperatures that only very special plastic films can nowadays stand. The properties of these substrates can be varied within a relatively large range by the selection of raw materials and their relative proportions. A semiindustrial scale pilot line was successfully used to produce smooth, flexible, and nanoporous composites, and their performance was tested in a double functional separator-substrate element in supercapacitors. The nanostructural carbon films printed on the composite worked simultaneously as high surface area active electrodes and current collectors. Low-cost supercapacitors made from environmentally friendly materials have significant potential for use in flexible, wearable, and disposable low-end products.

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        Maternal Genetic Variants of IL4/IL13 Pathway Genes on IgE With “Western or Eastern Environments/Lifestyles”

        Guicheng Zhang,Siew-Kim Khoo,Mika J Mäkelä,Pierre Candelaria,Catherine M Hayden,Leena von Hertzen,Tiina Laatikainen,Erkki Vartiainen,Jack Goldblatt,Tari Haahtela,Peter N LeSouëf1 대한천식알레르기학회 2014 Allergy, Asthma & Immunology Research Vol.6 No.4

        Purpose: We investigated maternal genetic effects of four IL-4/IL-13 pathway genes as well as their interactions with the “Western or Easternlifestyles/environments” on IgE in Karelian children. Methods: This study included 609 children and their mothers. Total IgE levels in children andmothers were measured and 10 single nucleotide polymorphisms (SNPs) in IL-4, IL-4Ra, IL-13, and STAT6 were genotyped in mothers and their children. Results: The maternal G allele of IL-13 130 (rs20541) was significantly (P=0.001) associated with decreased IgE in children in the Karelianpopulation (Pooling Finnish and Russian children), as well as in Finnish (P=0.030) and Russian children (P=0.018). The IgE levels were significantly(P=0.001) higher in Russian children whose mothers were homozygous for the G allele of the IL-4Ra 50 (rs1805010) SNP than that in Russian childrenof mothers who were AG heterozygotes or AA homozygotes. After accounting for children’s genotypes, we observed interactive effects on children’sIgE for maternal IL-13 130 genotypes (P=0.014) and maternal IL-4Ra 50 genotypes (P=0.0003) with “Western or Eastern” lifestyles/environments. With the adjustment for multiple comparisons using a false discovery rate (FDR) of 0.05, the interactive effect of the maternal IL-4Ra 50 SNP wassignificant. Conclusion: Maternal genetic variants in IL-4/IL-13 pathway genes, such as IL-13 130 and IL-4Ra50, influenced IgE levels in schoolchildren that were independent of the children’s genetic effects. These effects differ in “Western or Eastern” environments.

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