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      • KCI등재

        Impact of Puberty in Pediatric Migraine: A Pilot Prospective Study

        Elena Fonseca,Marta Torres-Ferrús,Víctor José Gallardo,Alfons Macaya,Patricia Pozo-Rosich 대한신경과학회 2020 Journal of Clinical Neurology Vol.16 No.3

        Background and Purpose The short-term evolution of pediatric migraine remains unclear. We aimed to describe the evolution of migraine before and after puberty and its relationship with lifestyle habits. Methods We prospectively selected prepuberal patients from a neuropediatric unit who had a migraine diagnosis. Their medical history, migraine characteristics and impact, and lifestyle habits were recorded at the baseline visit. After 2 years we performed a telephone follow-up assessment. Results Nineteen patients were recruited (age 10.2±2.9 years, mean±SD; 57.9% female), of whom 27.5% had migraine with aura. The accompanying symptoms had changed at the follow- up, with significantly higher prevalence rates of dizziness (44.4% vs. 88.9%), vertigo (11.1% vs. 66.7%), mood changes (38.9% vs 83.3%), confusion (5.6% vs. 77.8%), and allodynia (27.8% vs. 61.1%). Sleep disturbances (5.6% vs. 38.9%) and schedule changes (0% vs. 38.9%) increased significantly as triggers. Prodromal symptoms became more prevalent (16.7% vs. 50%), with a higher proportion of sleep disturbances reported (50.0% vs. 87.5%). Conclusions Prodromal symptoms increase in pediatric migraine after 2 years, and some trigger factors for migraine become more prevalent, including sleep disturbances. New accompanying symptoms are also identified. These changes provide information about how migraine changes during puberty along with physical and lifestyle changes, and represent a dynamic physiopathological process that deserves more research

      • KCI등재

        Study of the Dependency of the Specific Power Absorption Rate on Several Characteristics of the Excitation Magnetic Signal when Irradiating a SPION-containing Ferrofluid

        Alejandra Mina Rosales,Elena Aznar,Carmen Coll,Ruben A. Garcia Mendoza,A. Lorena Urbano Bojorge,Nazario Felix Gonzalez,Ramon Martinez-Manez,Francisco del Pozo Guerrero,Jose Javier Serrano Olmedo 한국자기학회 2016 Journal of Magnetics Vol.21 No.3

        Magnetic hyperthermia mediated by superparamagnetic particles is mainly based in sinusoidal waveforms as excitation signals. Temperature changes are conventionally explained by rotation of the particles in the surrounding medium. This is a hypothesis quite questionable since habitual experimental setups only produce changes in the magnetic module, not in the field lines trajectories. Theoretical results were tested by changing the waveform of the exciting signal in order to compare non-sinusoidal signals against sinusoidal signals. Experiments were done at different frequencies: 200 ㎑, 400 ㎑, 600 ㎑, 800 ㎑ and 1 ㎒. Superparamagnetic Iron Oxide samples (SPION), made of magnetite (Fe3O4) and suspended in water (100 ㎎/ml), were used. Magnetic field strength varies from 0.1 ± 0.015 KA/m to 0.6 ± 0.015 KA/m. In this study was observed that the power loss depends on the applied frequency: for 1 to 2.5 RMS current the responses for each signal are part of the higher section of the exponential function, and for 3.5 to 8 RMS current the response is clearly the decrement exponential function’s tale (under 1 × 10³ LER/gr).

      • KCI등재

        Two cases of an atypical presentation of necrotizing stomatitis

        Antonio Magan-Fernandez,Francisco O’Valle,Elena Pozo,Jose Liebana,Francisco Mesa 대한치주과학회 2015 Journal of Periodontal & Implant Science Vol.45 No.6

        Purpose: The purpose of this report was to describe the clinical and microbiological characteristicsof two rare cases of necrotizing stomatitis, and the outcomes of a non-invasivetreatment protocol applied in both cases. Methods: We report two cases of necrotizing stomatitis in a rare location in the hard palateof a 40-year-old woman and a 28-year-old man. Neither had a relevant medical historyand both presented with highly painful ulceration in the palate and gingival margin thatwas accompanied by suppuration and necrosis. 3% hydrogen peroxide was applied to thelesions using sterile swabs, and antibiotic and anti-inflammatory treatment was prescribedto both patients in addition to two daily oral rinses of 0.2% chlorhexidine. Results: In both cases, radiological examination ruled out bone involvement, and exfoliativecytology revealed a large inflammatory component and the presence of forms compatiblewith fusobacteria and spirochetes. There was a rapid response to treatment and amajor improvement was observed after 48 hours, with almost complete resolution of theulcerated lesions and detachment of necrotic areas with partial decapitation of gingivalpapillae. Conclusions: Necrotizing periodontal lesions can hinder periodontal probing and the mechanicalremoval of plaque in some cases due to the extreme pain suffered by the patients. We present a non-invasive treatment approach that can manage these situations effectively.

      • SCIESCOPUSKCI등재

        Two cases of an atypical presentation of necrotizing stomatitis

        Magan-Fernandez, Antonio,O'Valle, Francisco,Pozo, Elena,Liebana, Jose,Mesa, Francisco Korean Academy of Periodontology 2015 Journal of Periodontal & Implant Science Vol.45 No.6

        Purpose: The purpose of this report was to describe the clinical and microbiological characteristics of two rare cases of necrotizing stomatitis, and the outcomes of a non-invasive treatment protocol applied in both cases. Methods: We report two cases of necrotizing stomatitis in a rare location in the hard palate of a 40-year-old woman and a 28-year-old man. Neither had a relevant medical history and both presented with highly painful ulceration in the palate and gingival margin that was accompanied by suppuration and necrosis. 3% hydrogen peroxide was applied to the lesions using sterile swabs, and antibiotic and anti-inflammatory treatment was prescribed to both patients in addition to two daily oral rinses of 0.2% chlorhexidine. Results: In both cases, radiological examination ruled out bone involvement, and exfoliative cytology revealed a large inflammatory component and the presence of forms compatible with fusobacteria and spirochetes. There was a rapid response to treatment and a major improvement was observed after 48 hours, with almost complete resolution of the ulcerated lesions and detachment of necrotic areas with partial decapitation of gingival papillae. Conclusions: Necrotizing periodontal lesions can hinder periodontal probing and the mechanical removal of plaque in some cases due to the extreme pain suffered by the patients. We present a non-invasive treatment approach that can manage these situations effectively.

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