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Diaz, Edgar A.,Chung, Yeonseung,Papapostolou, Vasileios,Lawrence, Joy,Long, Mark S.,Hatakeyama, Vivian,Gomes, Brenno,Calil, Yasser,Sato, Rodrigo,Koutrakis, Petros,Godleski, John J. Informa Healthcare 2012 Inhalation toxicology Vol.24 No.5
<P>The study presented here is a laboratory pilot study using diluted car exhaust from a single vehicle to assess differences in toxicological response between primary emissions and secondary products resulting from atmospheric photochemical reactions of gas phase compounds with O<SUB>3</SUB>, OH and other radicals. Sprague Dawley rats were exposed for 5 h to either filtered room air (sham) or one of two different atmospheres: (i) diluted car exhaust (P)+Mt. Saint Helens Ash (MSHA); (ii) P+MSHA+secondary organic aerosol (SOA, formed during simulated photochemical aging of diluted exhaust). Primary and secondary gases were removed using a nonselective diffusion denuder. Continuous respiratory data was collected during the exposure, and bronchoalveolar lavage (BAL) and complete blood counts (CBC) were performed 24 h after exposure. ANOVA models were used to assess the exposure effect and to compare those effects across different exposure types. Total average exposures were 363 ± 66 μg/m<SUP>3</SUP> P+MSHA and 212 ± 95 µg/m<SUP>3</SUP> P+MSHA+SOA. For both exposures, we observed decreases in breathing rate, tidal and minute volumes (TV, MV) and peak and median flows (PIF, PEF and EF50) along with increases in breathing cycle times (Ti, Te) compared to sham. These results indicate that the animals are changing their breathing pattern with these test atmospheres. Exposure to P+MSHA+SOA produced significant increases in total cells, macrophages and neutrophils in the BAL and <I>in vivo</I> chemiluminescence of the lung. There were no significant differences in CBC parameters. Our data suggest that simulated atmospheric photochemistry, producing SOA in the P+MSHA+SOA exposures, enhanced the toxicity of vehicular emissions.</P>
Human Anthropomorphic Gripper as an Automation Tool
Alvaro Uribe,Edgar Diaz,Hernando Leon 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10
This paper presents the design, development and implementation of a 14 DOF human anthropomorphic pneumatic gripper as a tool for teaching automation basics using pneumatics and PLCs. The dexterity of the human hand allows several types of power and precision grasps for interacting with various scenarios, these features have inspired the development of robotics mimicking the human hand in applications such as collaborative robotics workcells, where each finger is an actuated mechanism with a specific task. Collaborative actions through pneumatic and PLC programming basics using this hand allows enhancing the user’s knowledge based on concepts and familiarity with the device. The pneumatic hand can be used on site, with the user directly operating it, and offline with a virtual reality tool for offering simultaneous accessible devices when multiple users need the hand. Robotics currently assists training surgical procedures, manipulation of elements in hazardous environments for us, kinematics, dynamics and path planning simulations for various industrial processes, or as didactic tools for inspiring school students for working with robotics. The pneumatic hand system is composed of an actuation, control and teleoperation subsystems, these interact for simulating the muscles, and the user’s inputs for executing the chosen tasks.