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      • Hazardous Metal Pollution in the Republic of Fiji and the Need to Elicit Human Exposure

        박은기,Donald Wilson,최현주,Colleen Turaga Wilson,Susumu Ueno 환경독성보건학회 2013 환경독성보건학회지 Vol.28 No.-

        The fact that hazardous metals do not bio-degrade or bio-deteriorate translates to long-lastingenvironmental effects. In the context of evidently rapid global industrialization, thisought to warrant serious caution, particularly in developing countries. In the Republic of Fiji,a developing country in the South Pacific, several different environmental studies over thepast 20 years have shown levels of lead, copper, zinc and iron in sediments of the SuvaHarbor to be 6.2, 3.9, 3.3 and 2.1 times more than the accepted background reference levels,respectively. High levels of mercury have also been reported in lagoon shellfish. Thesedata inevitably warrant thorough assessment of the waste practices of industries locatedupstream from the estuaries, but in addition, an exposure and health impact assessmenthas never been conducted. Relevant government departments are duty-bound, at least tothe general public that reside in and consume seafood from the vicinities of the Suva Harbor,to investigate possible human effects of the elevated hazardous metal concentrationsfound consistently in 20 years of surface sediment analysis. Furthermore, pollution of theintermediate food web with hazardous metals should be investigated, regardless of whetherhuman effects are eventually confirmed present or not.

      • KCI등재후보

        Awareness of Asbestos and Action Plans for Its Exposure can Help Lives Exposed to Asbestos

        이후장,박은기,Donald Wilson,Engin Tutkun,옥철호 한국산업안전보건공단 산업안전보건연구원 2013 Safety and health at work Vol.4 No.2

        Despite the fact that asbestos is a known carcinogen to humans, it is still used in industrialized countries, especially Asian countries. The global incidence of asbestos-related diseases (ARDs) due to the past use of asbestos, continues to increase, although many countries have adopted a total ban on asbestos use. The implementation of effective strategies to eliminate ARDs is therefore an important challenge in Asia, where asbestos is still mined and consumed. Collaborative efforts and strategies at the local and international levels are vital, in the pursuit toward the elimination of ARDs in this region.

      • Hazardous Metal Pollution in the Republic of Fiji and the Need to Elicit Human Exposure

        Park, Eun-Kee,Wilson, Donald,Choi, Hyun-Ju,Wilson, Colleen Turaga,Ueno, Susumu The Korean Society of Environmental Toxicology 2013 환경독성보건학회지 Vol.28 No.-

        The fact that hazardous metals do not bio-degrade or bio-deteriorate translates to long-lasting environmental effects. In the context of evidently rapid global industrialization, this ought to warrant serious caution, particularly in developing countries. In the Republic of Fiji, a developing country in the South Pacific, several different environmental studies over the past 20 years have shown levels of lead, copper, zinc and iron in sediments of the Suva Harbor to be 6.2, 3.9, 3.3 and 2.1 times more than the accepted background reference levels, respectively. High levels of mercury have also been reported in lagoon shellfish. These data inevitably warrant thorough assessment of the waste practices of industries located upstream from the estuaries, but in addition, an exposure and health impact assessment has never been conducted. Relevant government departments are duty-bound, at least to the general public that reside in and consume seafood from the vicinities of the Suva Harbor, to investigate possible human effects of the elevated hazardous metal concentrations found consistently in 20 years of surface sediment analysis. Furthermore, pollution of the intermediate food web with hazardous metals should be investigated, regardless of whether human effects are eventually confirmed present or not.

      • KCI등재

        Lung Function Profiles among Individuals with Nonmalignant Asbestos-related Disorders

        박은기,Deborah H. Yates,Donald Wilson 한국산업안전보건공단 산업안전보건연구원 2014 Safety and health at work Vol.5 No.4

        Background: Inhalation of asbestos fibers can lead to adverse health effects on the lungs. This studydescribes lung function profiles among individuals with nonmalignant asbestos-related disorders (ARDs). Methods: The study population was from the Workers’ Compensation (Dust Diseases) Board of NewSouth Wales, Sydney, Australia. Lung function measurements were conducted in males with asbestosis(n ¼ 26), diffuse pleural thickening (DPT; n ¼ 129), asbestosis and DPT (n ¼ 14), pleural plaques only(n ¼ 160) and also apparently healthy individuals with a history of asbestos exposure (n ¼ 248). Standardizedspirometric and single-breath diffusing capacity for carbon monoxide (DLCO) measurementswere used. Results: Mean age [standard deviation (SD)] was 66.7 (10.3) years for all participants. Current andex-smokers among all participants comprised about 9.0% and 54.8%, respectively. Median pack-years (SD)of smoking for ex- and current-smokers were 22.7 (19.9). Overall 222 participants (38.6%) and 139participants (24.2%) had forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC)measurements < 80% predicted, and 217 participants (37.7%) had FEV1/FVC results < 70%. A total of 249individuals (43.8%) had DLco values < 80% predicted and only 75 (13.2%) had DLco/VA results < 80%predicted. A total of 147 participants (25.6%) had peak expiratory flow (PEF) measurements < 80%predicted. The presence of ARDs lowered the lung function measurements compared to those of healthyindividuals exposed to asbestos. Conclusion: Lung function measurement differs in individuals with different ARDs. Monitoring of lung

      • SCOPUSKCI등재

        Awareness of Asbestos and Action Plans for Its Exposure can Help Lives Exposed to Asbestos

        Lee, Hu-Jang,Park, Eun-Kee,Wilson, Donald,Tutkun, Engin,Oak, Chulho Occupational Safety and Health Research Institute 2013 Safety and health at work Vol.4 No.2

        Despite the fact that asbestos is a known carcinogen to humans, it is still used in industrialized countries, especially Asian countries. The global incidence of asbestos-related diseases (ARDs) due to the past use of asbestos, continues to increase, although many countries have adopted a total ban on asbestos use. The implementation of effective strategies to eliminate ARDs is therefore an important challenge in Asia, where asbestos is still mined and consumed. Collaborative efforts and strategies at the local and international levels are vital, in the pursuit toward the elimination of ARDs in this region.

      • SCOPUSKCI등재

        Lung Function Profiles among Individuals with Nonmalignant Asbestos-related Disorders

        Park, Eun-Kee,Yates, Deborah H.,Wilson, Donald Occupational Safety and Health Research Institute 2014 Safety and health at work Vol.5 No.4

        Background: Inhalation of asbestos fibers can lead to adverse health effects on the lungs. This study describes lung function profiles among individuals with nonmalignant asbestos-related disorders (ARDs). Methods: The study population was from the Workers' Compensation (Dust Diseases) Board of New South Wales, Sydney, Australia. Lung function measurements were conducted in males with asbestosis (n = 26), diffuse pleural thickening (DPT; n = 129), asbestosis and DPT (n = 14), pleural plaques only (n = 160) and also apparently healthy individuals with a history of asbestos exposure (n = 248). Standardized spirometric and single-breath diffusing capacity for carbon monoxide ($DL_{CO}$) measurements were used. Results: Mean age [standard deviation (SD)] was 66.7 (10.3) years for all participants. Current and ex-smokers among all participants comprised about 9.0% and 54.8%, respectively. Median pack-years (SD) of smoking for ex- and current-smokers were 22.7 (19.9). Overall 222 participants (38.6%) and 139 participants (24.2%) had forced expiratory volume in 1 second ($FEV_1$) and forced vital capacity (FVC) measurements < 80% predicted, and 217 participants (37.7%) had $FEV_1/FVC$ results < 70%. A total of 249 individuals (43.8%) had DLCO values < 80% predicted and only 75 (13.2%) had DLCO/VA results < 80% predicted. A total of 147 participants (25.6%) had peak expiratory flow (PEF) measurements < 80% predicted. The presence of ARDs lowered the lung function measurements compared to those of healthy individuals exposed to asbestos. Conclusion: Lung function measurement differs in individuals with different ARDs. Monitoring of lung function among asbestos-exposed populations is a simple means of facilitating earlier interventions.

      • SCOPUSKCI등재

        Follow-up of Soluble Mesothelin-Related Protein Levels in Participants With Asbestos-Related Disorders

        Park, Eun-Kee,Johnson, Anthony R.,Wilson, Donald,Thomas, Paul S.,Yates, Deborah H. Occupational Safety and Health Research Institute 2020 Safety and health at work Vol.11 No.4

        Background: Asbestos exposure is associated with the development of the cancer malignant mesothelioma (MM). Measurement of soluble mesothelin-related protein (SMRP) has been suggested as a method for detection of MM in its early stages. We prospectively examined SMRP levels in participants with asbestos exposure who are a group at a high risk of development of MM. Methods: This study was a follow-up of our cohort of 322 asbestos-exposed participants. No further participants developed MM or malignancy over the study period. Mean follow-up time was 22.9 months. Results: Mean (standard deviation) SMRP levels at baseline and follow-up were 0.94 (0.79) and 0.91 (0.86) nmol/L (p = 0.1033), respectively. Mean SMRP levels of the healthy individuals exposed to asbestos at baseline was significantly lower than those of participants with asbestosis and pleural plaques alone; similar patterns were found on follow-up measurements. There was a statistically significant effect of age on serial SMRP measurements. Our study confirms higher levels in participants with nonmalignant asbestos-related disorders. Levels decreased in asbestos-related disorders other than asbestosis, where a small increase was observed. We did not detect any further cases of malignancy. Conclusion: Monitoring programs for early detection of MM need to take into account increased SMRP levels found in benign asbestos-related diseases.

      • SCOPUSKCI등재

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