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이원도(Weon-do Lee) 동남어문학회 2004 동남어문논집 Vol.18 No.-
Body in Sang Lee's poetry is an important perceptional object and is a medium of his self-research. And body is a subject mater never treated by his contempories and even by his precursors. Body to him is a physical foundation through which his poetic self accepts external world and makes his surroundings new. We can see his consciousness in which he as a doctor diagnoses himself, looks at another body in the mirror and goes toward compromise and correspondence whitout success. In poetry he ignores grammars intentionally. This means he does not respect literary tradition and history, and he, parodoxically, opens the door to death of a body in an isolated consciousness from reality. Human body is, as Tuan put it, an image of universe and a center of universal frame. Body is a part of concrete universe, a condition to experience external world and an object to the world. In narrator-author's consciousness lineal progression does not exist-his past ends in the past, his present does not proceed to the future and his future means only closure and does not have any continous significance. The death of body denotes total biological close which terminates all human construction. His symmetrical meeting of ordinary-self and idaal-self in the mirror shows his formation of self-socscious world and existential consciousness. This is possible by his body capable of seeing another world rather than by the intellectual construction of his self. In the basis of his poetry, the following images are abundant: adherence to the closed boyhood, isolation of hopeless otherness, ambiguities of eroticism, symbol of physical otherness and self-consciousness within and without the mirror.
Bridgman 방법으로 성장된 Cd0.8Mn0.2Te 의 전기적 특성연구
이정주,황도원,유인근,박영신 慶尙大學校 1991 論文集 Vol.30 No.2
본 실험에서 자체 제작한 전기로를 이용하여 Bridgman-Stockbarger 방법으로 Cd0.8Mn0.2Te를 성장시켜 전기적 특성을 조사하였는데, 주로 Hall effect 측정과 TSC측정으로 비저항, Hall 이동도, Hall계수, carrier 농도, ,trap energy level, 이탈 진동수, 포획 단면적 등을 구하였다.
함암요법으로 골수기능이 억제된 악성종양환자에서 rhG-CSF의 임상적 효과
김원민,서영환,조경상,유병전,김상도,이승일,정춘해 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2
We have studied the efficacy of rhG-CSF in patients with non-hodgkin's lymphoma, acute leukemia, and small cell lung cancer undergoing anticancer chemotherapy. These patients were below leukocyte count 3,000 cubic millimeter due to myelosuppression induced by the first cycle of intensive chemotherapy. Treatment with rhG-CSF (100㎍ per square meter of body surface area per day in a 30-minute intravenous infusion) was begun two days and for 14 consecutive days after the end of the second cycle of chemotherapy. The results were as follows. 1. The onset of myelosuppression was 6 days after chemotherapy, and the onset of recovery was 16.7 days after chemotherapy, and the duration of granulocytopenia was 10.7 days in patients with malignant tumor during contrast period. 2. The duration of granulocytopenia was shortened 5.2 days in patients administered rhG-CSF than without rhG-CSF, and we observed the shortest duration of granulocytopenia with increasing granulocyte in patients with small cell lung cancer. 3. Observing the differential count of leukocyte checked the highest level of leukocyte in contrast and rhG-CSF period, the persentage of neutrophil was increased in patients with acute leukemia and small cell lung cancer during rhG-CSF period, but not increased in patients with non-hodgkin's lymphoma. 4. rhG-CSF was not influenced on liver faction, renal fuction, uric acid, and glucose metabolism, also had no effect on recovery of platelet. In conclusion, rhG-CSF can be administered to patients with hematologic or nonhematologic malignant tumor that myelosuppression induced by anticancer chemotherapy result in shortening the duration of granulocytopenia and increasing the peripheral neutrophil, therefore full dose chemotherapy can be administered on time, and rhG-CSF may reduce the morbidity and mortality of patients with malignant tumor undergoing chemotherapy.
Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth
( Weon Ju Lee ),( Hyun Bo Sim ),( Yong Hyun Jang ),( Seok Jong Lee ),( Do Won Kim ),( Soon Ho Yim ) 대한피부과학회 2016 Annals of Dermatology Vol.28 No.4
Background: Pattern hair loss is a very common problem. Although effective therapeutics for the treatment of pattern hair loss have been used, novel therapeutic modalities are still required to enhance hair growth. Objective: We investigated the efficacy and safety of a complex (ALAVAX) of 5-aminolevulinic acid (5-ALA) and glycyl-histidyl-lysine (GHK) peptide for the treatment of pattern hair loss. Methods: Forty-five patients with male pattern hair loss were treated with ALAVAX 100 mg/ml (group A), ALAVAX 50 mg/ml (group B) or placebo (group C) once a day for 6 months. Total hair count, hair length, hair thickness, patient’s assessment and adverse events were evaluated at month 1, 3, and 6. Results: An increase in hair count for 6 months was 52.6 (p<0.05) in group A, 71.5 (p<0.05) in group B, and 9.6 in group C. The ratio of changes in hair count between group B (2.38) and group C (1.21) at 6 months showed a statistically significant difference (p<0.05). The proportion above good satisfaction was higher in group A (26.7%) than in the other groups (group B: 14.3%, group C: 7.1%). There was no statistically significant difference in hair length and hair thickness among 3 groups at 6 months. There was no adverse event in 3 groups. Conclusion: Our study showed that a complex of 5-ALA and GHK peptide may be considered as one of the complementary agents for the treatment of male pat-tern hair loss. (Ann Dermatol 28(4) 438∼443, 2016)
A fraction of deep vascular birthmarks are true deep hemangiomas of infancy
Lee, Seok-Jong,Shin, Dong Ju,Kim, Ho Youn,Lee, Weon Ju,Kim, Do Won,Chung, Ho Yun,Baik, Seung Kug,Lee, Jong Min,Huh, Seung,Yoon, Ghil Suk Blackwell Publishing Ltd 2009 International journal of dermatology Vol.48 No.8
<P>Abstract</P><P>Background </P><P>Deeply-located vascular birthmarks have been traditionally regarded as being identical to a deep type of hemangioma of infancy (HOI). However, there is increasing evidence that some venous malformations also mimic these deep type of HOIs clinically. This study investigates how many, if not all, deep vascular birthmarks are deep type HOIs.</P><P>Methods </P><P>Nineteen cases were selected on the basis of the clinical features of deeply-located vascular birthmarks. Hematoxylin-eosin slides were reviewed and immunohistochemistries were performed using CD31, D2-40 and GLUT1 to confirm diagnoses before they were compared with the clinicoradiologic review by specialists other than dermatopathologists.</P><P>Results </P><P>Only 4 patients out of a total of 19 cases were strongly positive for GLUT1 staining and turned out to be true deep HOIs. The remaining were comprised of 6 venous malformations (31.6%), 3 lymphatic malformations (15.8%), 1 glomangioma (5.3%) and 5 tufted angiomas (26.3%).</P><P>Conclusion </P><P>It was demonstrated that all deeply-located vascular birthmarks are not true deep HOIs. It is recommended that diagnosis for HOI be carried out cautiously earlier in life using GLUT1 in addition to clinical features. This would help prevent patients from being misled by anticipating the spontaneous involution in all deeply-located vascular birthmarks.</P>
( Weon Ju Lee ),( Hyun Bo Sim ),( Sang Lim Kim ),( Yong Hyun Jang ),( Seok Jong Lee ),( Do Won Kim ),( Kyung Chan Kim ),( Soon Ho Yim ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: 5-aminolevulinic acid (5-ALA) stimulates murine hair growth in vivo study. Glycyl- Histidyl-Lysine (GHK) peptide increases hair follicle size and stimulates stem cell proliferation. Objectives: To investigate the efficacy of a combination of 5-ALA and GHK peptide (ALAVAX) on hair growth Methods: Cell culture of keratinocyte, melanocytes and fibroblast was performed for MTT assay. Seven-week old C57BL/6N mice were treated with 100 mg/ml ALA ± 5-minute red or blue LED or 100 mg/ml ALAVAX ± 5-minute red or blue LED once a day for 24 days for evaluation of hair growth. Cultured human hair organs were treated with 100 times-diluted ALAVAX ± 20-minute red LED for 7 days. Forty five patients with male pattern hair loss were treated with ALAVAX once a day for 6 months. Total hair count, hair diameter, hair length and patients’ assessment were evaluated at week 4, 12 and 24 after treatment. The penetration of ALAVAX into hair follicles was examined under the fluorescent microscopy. Results: Hair growth was most conspicuous in mice treated with ALAVAX + red LED. Hair growth of cultured hair organs was significantly increased after treatment with ALAVAX only. Total hair count, hairlength and patients’ assessment in humans was significantly improved in the group treated with ALAVAX. No adverse event was reported. The penetration of ALAVAX in human hair follicles was prominent. Conclusion: ALAVAX could be considered as one of the useful agents for the treatment of male pattern hair loss.