Is catechol-o-methyltransferase gene polymorphism a risk factor in the development of premenstrual syndrome?

Deveci, Esma Ozturk,Incebiyik, Adnan,Selek, Salih,Camuzcuoglu, Aysun,Hilali, Nese Gul,Camuzcuoglu, Hakan,Erdal, Mehmet Emin,Vural, Mehmet The Korean Society for Reproductive Medicine 2014 Clinical and Experimental Reproductive Medicine Vol.41 No.2

Objective: The objective of this study was to investigate whether there was a correlation between catechol-o-methyltransferase (COMT) gene polymorphism, which is believed to play a role in the etiology of psychotic disorders, and premenstrual syndrome (PMS). Methods: Fifty-three women with regular menstrual cycles, aged between 18 and 46 years and diagnosed with PMS according to the American Congress of Obstetrics and Gynecology criteria were included in this study as the study group, and 53 healthy women having no health problems were selected as the controls. Venous blood was collected from all patients included in the study and kept at $-18^{\circ}C$ prior to analysis. Results: There was no significant difference between the groups in terms of demographic features such as age, body mass index, number of pregnancies, parity, and number of children. No statistically significant difference was observed in terms of COMT gene polymorphism (p=0.61) between women in the PMS and the control groups. However, a significant difference was found between arthralgia, which is an indicator of PMS, and low-enzyme activity COMT gene (Met/Met) polymorphism (p=0.04). Conclusion: These results suggested that there was no significant relationship between PMS and COMT gene polymorphism. Since we could not find a direct correlation between the COMT gene polymorphism and PMS, further studies including alternative neurotransmitter pathways are needed to find an effective treatment for this disease.

Adsorption of hexavalent chromium from aqueous solutions by bio-chars obtained during biomass pyrolysis

Huseyin Deveci,Yakup Kar 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.1

In this study, bio-chars were evaluated as a potential adsorbent for the removal of Cr (VI) ions from aqueous solutions. The effects of some important parameters including initial pH (1.5–7), adsorbent dose (0.2–5 g/L), contact time (5–900 min) and initial Cr (VI) ion concentration (5–75 mg/L) were tested on the removal of Cr (VI) ions from aqueous solution in batch experiments. Maximum adsorption capacities of the tested bio-chars under the certain experimental conditions determined as optimal were 3.53 mg/g for NCBC, 3.97 mg/g for NZCBC and 6.08 mg/g for ACBC, respectively. Results of the kinetic and isotherm modeling studies revealed that the adsorption data fitted well with a pseudo-second order and Langmuir model. In among the tested bio-chars, the bio-char (ACBC) was largely equivalent to activated carbon: AC (9.97 mg/g) in terms of adsorption capacity. All results indicated that the bio-chars had higher adsorption capacity than some chars and activated carbons reported previously, and also that these bio-chars could be used successfully as low-cost adsorbents for the removal of chromium ions from aqueous solutions under the tested experimental conditions.

The comparison of single incision laparoscopic cholecystectomy and three port laparoscopic cholecystectomy

Ugur Deveci,Umut Barbaros,Mahmut Sertan Kapakli,Manuk Norayk Manukyan,Selcuk ?im?ek,Abut Kebudi,Selcuk Mercan 대한외과학회 2013 Annals of Surgical Treatment and Research(ASRT) Vol.85 No.6

Purpose: Laparoscopic techniques have allowed surgeons to perform complicated intra-abdominal surgery with minimal trauma. Single incision laparoscopic surgery (SILS) was developed with the aim of reducing the invasiveness of conventional laparoscopy. In this study we aimed to compare results of SILS cholecystectomy and three port conventional laparoscopic (TPCL) cholecystectomy prospectively. Methods: In this prospective study, 100 patients who underwent laparoscopic cholecystectomy for gallbladder disease were randomly allocated to SILS cholecystectomy (group 1) or TPCL cholecystectomy (group 2). Demographics, pathologic diagnosis, operating time, blood loss, length of hospital stay, complications, pain score, conversion rate, and satisfaction of cosmetic outcome were recorded. Results: Forty-four SILS cholesystectomies (88%) and 42 TPCL cholecystectomies (84%) were completed successfully. Conversion to open surgery was required for 4 cases in group 1 and 6 cases in group 2. Operating time was significantly longer in group 1 compared with group 2 (73 minutes vs. 48 minutes; P < 0.05). Higher pain scores were observed in group 1 versus group 2 in postoperative day 1 (P < 0.05). There was higher cosmetic satisfaction in group 1 (P < 0.05). Conclusion: SILS cholecystectomy performed by experienced surgeons is at least as successful, feasible, effective and safe as a TPCL cholecystectomy. Surgeons performing SILS should have a firm foundation of advanced minimal access surgical skills and a cautious, gradated approach to attempt the various procedures. Prospective randomized studies comparing single access versus conventional multiport laparoscopic cholecystectomy, with large volumes and long-term followup, are needed to confirm our initial experience. (ClinicalTrials.gov Identifier:NCT01772745.)

A study on recurrence relations for binary sequence matrices

Omur deveci,A.G. Shannon 장전수학회 2023 Advanced Studies in Contemporary Mathematics Vol.33 No.1

A study on recurrence relations for binary sequence matrices

Ganoderma Lucidum Protects Rat Brain Tissue Against Trauma-Induced Oxidative Stress

Özevren Hüseyin,İrtegün Sevgi,Deveci Engin,Aşır Fırat,Pektanç Gülsüm,Deveci Şenay 대한신경손상학회 2017 Korean Journal of Neurotrauma Vol.13 No.2

Objective: Traumatic brain injury causes tissue damage, breakdown of cerebral blood flow and metabolic regulation. Thisstudy aims to investigate the protective influence of antioxidant Ganoderma lucidum (G. lucidum) polysaccharides (GLPs)on brain injury in brain-traumatized rats. Methods: Sprague-Dawley conducted a head-traumatized method on rats by dropping off 300 g weight from 1 m height. Groups were categorized as control, G. lucidum, trauma, trauma+ G. lucidum (20 mL/kg per day via gastric gavage). Braintissues were dissected from anesthetized rats 7 days after injury. For biochemical analysis, malondialdehyde, glutathioneand myeloperoxidase values were measured. Results: In histopathological examination, neuronal damage in brain cortex and changes in blood brain barrier were observed. In the analysis of immunohistochemical and western blot, p38 mitogen-activated protein kinase, vascular endothelial growth factor and cluster of differentiation 68 expression levels were shown. These analyzes demonstrated the benefcial effects of GLPs on brain injury. Conclusion: We propose that GLPs treatment after brain injury could be an alternative treatment to decraseing inflammationand edema, preventing neuronal and glial cells degeneration if given in appropriate dosage and in particular time intervals.

Ganoderma Lucidum Protects Rat Brain Tissue Against Trauma-Induced Oxidative Stress

Özevren Hüseyin,İrtegün Sevgi,Deveci Engin,Aşır Fırat,Pektanç Gülsüm,Deveci Şenay 대한신경손상학회 2017 Korean Journal of Neurotrauma Vol.14 No.2

Objective: Traumatic brain injury causes tissue damage, breakdown of cerebral blood flow and metabolic regulation. Thisstudy aims to investigate the protective influence of antioxidant Ganoderma lucidum (G. lucidum) polysaccharides (GLPs)on brain injury in brain-traumatized rats. Methods: Sprague-Dawley conducted a head-traumatized method on rats by dropping off 300 g weight from 1 m height. Groups were categorized as control, G. lucidum, trauma, trauma+ G. lucidum (20 mL/kg per day via gastric gavage). Braintissues were dissected from anesthetized rats 7 days after injury. For biochemical analysis, malondialdehyde, glutathioneand myeloperoxidase values were measured. Results: In histopathological examination, neuronal damage in brain cortex and changes in blood brain barrier were observed. In the analysis of immunohistochemical and western blot, p38 mitogen-activated protein kinase, vascular endothelial growth factor and cluster of differentiation 68 expression levels were shown. These analyzes demonstrated the benefcial effects of GLPs on brain injury. Conclusion: We propose that GLPs treatment after brain injury could be an alternative treatment to decraseing inflammationand edema, preventing neuronal and glial cells degeneration if given in appropriate dosage and in particular time intervals.

The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model

M. Hamdi Muz,Figen Deveci,Yasemin Bulut,Nevin Ilhan,Hayrettin Yekeler,Teyfik Turgut 생화학분자생물학회 2006 Experimental and molecular medicine Vol.38 No.2

Synergistic effects of silica aerogels/xerogels on properties of polymer composites: A review

Gulcihan Guzel Kaya,Huseyin Deveci 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.89 No.-

The present review focuses on synergistic effectsof silica aerogels/xerogels on properties of polymercomposites. Infirst part of the review, synthesis of silica aerogels/xerogels from inexpensive silicaprecursors in addition to silicon alkoxides is explained in detail. The promising properties such as highlyporous structure, low density, high thermal stability, low thermal conductivity and acoustic velocity, andcontrollable hydrophobicity of silica aerogels/xerogels and their applications are enlarged upon. In otherpart of the review, enhanced properties of various polymer composites are summarized in the presenceof silica aerogel/xerogel asfiller. The significant improvements in thermal and sound insulationperformance, physicomechanical properties and service life under harsh environmental conditions ofpolymer composites including silica aerogel/xerogel are represented. The desirable properties of thepolymer composites extend potential high technology applications of these materials.

Predictive Role of Neutrophil Gelatinase-Associated Lipocalin in Early Diagnosis of Platin-Induced Renal Injury

Seker, Mehmet Metin,Deveci, Koksal,Seker, Ayse,Sancakdar, Enver,Yilmaz, Ali,Turesin, A. Kerim,Kacan, Turgut,Babacan, Nalan A. Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

Background: Acute kidney injury is an important issue in chemotherapy receiving patients an neutrophil gelatinase-associated lipocalin has been proposed as a novel marker. We here aimed to assess the role of urinary levels for assessment after platin exposure. Materials and Methods: Patients who had treated with cisplatin or carboplatin or oxaliplatin containg regimens were included in this study. Baseline and postchemotherapy serum urea, creatinine, urine neutrophil gelatinase-associated lipocalin and urine creatinine levels were determined. To avoid the effects of hydration during chemotherapy infusion the urinary neutrophil gelatinase-associated lipocalin/urine creatinine ratio was used to determine acute kidney injury. Results: Of a total of 42 patients receiving platin compounds,14 (33.3%) received cisplatin containing regimens, 14 (33.3%) received carboplatin and 14 (33.3%) oxaliplatin. The median age was 60 (37-76) years. Nineteen of the patients (45.2%) had lung cancer, 12 (28.6%) colorectal cancer and 11 (26.2%) others. The median pre and post chemotherapy urine neutrophil gelatinase-associated lipocalin/urine creatinin ratio was 15.6 ng/mg and 35.8 ng/mg (p=0.041) in the cisplatin group, 32.5 ng/mg and 86.3 ng/mg (p=0.004) in the carboplatin group and 40.9 ng/mg and 62.3 ng/mg (p=0.243) in the oxaliplatin group. Conclusions: Nephrotoxicity is a serious side effect of chemotherapeutic agentslike cisplatin and carbopaltin, but only to a lower extent oxaliplatin. All platin compounds must be used carefully and urine neutrophil gelatinase-associated lipocalin measurement seems to be promising in detecting acute kidney injury earlier than with creatinine.

RISING BINOMIAL COEFFICIENTS - TYPE 1: EXTENSIONS OF CARLITZ AND RIORDAN

ANTHONY G. SHANNON,ÖMÜR DEVECI 장전수학회 2020 Advanced Studies in Contemporary Mathematics Vol.30 No.2

Following some ideas initiated by Leonard Carlitz and John Riordan, this paper generalizes some properties of the ordinary binomial coecient through the use of rising factorials. Properties include connections with Beta and Gamma functions.