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- 저자 : Delgado Marín Juan Luis (검색결과 2 건)
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José Domingo Cruz-Labana,María Magdalena Crosby-Galván,Adriana Delgado-Alvarado,José Luis Alcántara-Carbajal,Juan Manuel Cuca-García,Luis Antonio Tarango-Arámbula 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.4
In Mexico the ant Liometopum apiculatum is an important insect nutritionally, economically and ecologically. Their larvae (“escamoles”) contain proteins, lipids, vitamins and minerals, the concentrations of which may be related with the type of vegetation where the ant forages. The objective of this study was to evaluate the content of macro and micro nutrients of L. apiculatum larvae collected in three types of vegetation in north-central Mexico. We determined content of moisture, crude protein, total lipids, crude fiber, ash, and nitrogen-free extract. The amino acids were analyzed by cationic Exchange chromatography with acid hydrolysis and fatty acids by gas chromatography and solvent extraction with sodium methoxide. The effect of vegetation type on nutrient content was determined with an ANOVA and Sheffé comparison of means (P < .05). The concentration of amino acids and fatty acids (FA) was analyzed with a Kruskall-Wallis test (P < .05). Significant differences were found in protein, lipids and ash (P < .0001) and moisture content (P < .0036). We identified 17 amino acids, which concentration differed by type of vegetation. There were no significant differences in fatty acids. It is likely that the differences in the concentrations of macronutrients are due to the diversity and differential density of the food components available in each type of vegetation for L. apiculatum, and that the number of types and quantity of amino acids and fatty acids depend on the chemical properties of the liquid secretions the ants obtain by trophobiosis.
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Early Effect of 0.005% Estriol Vaginal Gel on Symptoms and Signs of Vulvovaginal Atrophy
Lázaro-Carrasco de la Fuente Jesús,Cuerva González Marcos,González Rodríguez Silvia,Delgado Marín Juan Luis,Cuevas Castillo Carmen,Nieto Magro Concepción 대한폐경학회 2022 대한폐경학회지 Vol.28 No.2
Objectives: This study aims to assess the effect of ultralow dose 0.005% estriol vaginal gel in women with genitourinary syndrome of menopause (GSM).Methods: In this prospective and multicenter single-arm study, efficacy was assessed by the evaluation of the epithelial maturation value (MV), vaginal pH, symptoms and signs of vulvovaginal atrophy. Tolerability, acceptability, and the effect on intimate relationships were also evaluated.Results: We included 35 postmenopausal women with moderate-to-severe vaginal dryness. The most bothering symptom reported was vaginal dryness. The mean increase in the MV after 7 and 14 days of treatment were 22.1 (P < 0.001) and 39.9 (P < 0.001) points, with an increase in the superficial cells of 17.7 percentage points (pp) (95% confidence interval [CI], 7.9–27.4; P < 0.001) and 41.4 pp (95% CI, 28.2–54.6; P < 0.001) observed at the timepoints. Additionally, the pH decreased by 0.6 ± 0.7 (mean ± SD) at 7 days (P < 0.0001) and by 1.1 ± 0.8 at 14 days (P < 0.0001) from a baseline mean value of 6.3 ± 0.8. The severity of vaginal dryness (range, 0 [none] to 3 [severe]) was significantly reduced by a mean of 1.4 points (P < 0.0001) at 7 days and 2 points (P < 0.0001) at 14 days. Conclusions: Ultralow dose 0.005% estriol vaginal gel produced a rapid improvement of most relevant symptoms and signs of GSM. This clinically meaningful response was observed from the initial days of treatment, confirming a fast onset and a progressive action.
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