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RISS 인기검색어
- 검색키워드
- 저자 : Dedrick Kok Hong Chan (검색결과 2 건)
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Nasal Cavity Metastasis From Colorectal Cancer Represents End-Stage Disease and Should Be Palliated
Stephen Hwang,Dedrick Kok Hong Chan,Fredrik Petersson,Ker-Kan Tan 대한대장항문학회 2020 Annals of Coloproctolgy Vol.36 No.2
Nasal metastases from colorectal cancer is rare. The presentation of nasal metastases is often very similar to primary nasal sinus adenocarcinoma. A high index of suspicion is required, especially in patients who have had a previous history of colorectal carcinoma. Histology is ultimately required for diagnosis. We describe 2 cases of nasal metastases from colorectal carcinoma, and discuss the presentation, diagnosis and management of the case. Such metastatic disease ultimately represents end-stage malignancy, and patients should be palliated.
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Anal Adenocarcinoma Can Masquerade as Chronic Anal Fistula in Asians
Faith Qi-Hui Leong,Dedrick Kok Hong Chan,Ker-Kan Tan 대한대장항문학회 2019 Annals of Coloproctolgy Vol.35 No.1
Purpose: Perianal adenocarcinoma arising from a chronic anorectal fistula is a rare condition for which the natural history and optimal management are not well established. For that reason, we conducted a retrospective analysis of 5 consecutive patients with a perianal adenocarcinoma arising from a chronic anorectal fistula managed at our institution from January 2014 to December 2015. Methods: The patients were identified from a prospectively collected colorectal cancer database that included all patients managed for colorectal cancer at our institution. Results: The median age at diagnosis was 64 years (range, 55–72 years). Magnetic resonance imaging (MRI) was the initial investigation for all patients and showed a hyperintense T2-weighted image. One patient underwent an abdominoperineal resection following neoadjuvant chemoradiotherapy and remained disease free during the 12-month follow-up. Three patients received neoadjuvant therapy with intent for surgery, but did not undergo surgery due to either worsening health or metastatic spread. One patient declined intervention. The median overall survival was 10.5 months (range, 2–19 months). Conclusion: A high index of suspicion is required to make a clinical diagnosis of an anal adenocarcinoma arising from a chronic fistula. Histologic diagnosis must be achieved to confirm the diagnosis. Multimodal therapy with neoadjuvant chemoradiotherapy followed by abdominoperineal resection is the treatment of choice.
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