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A Clinical Analysis of 100 Cases of Gasless Endoscopic Thyroidectomy
Jeong Soo Kim(김정수),Chung Goo Kim(김정구),Kee Hwan Kim(김기환),Chang Hyuck Ahn(안창혁),Hae Myung Jeon(전해명),Keun Woo Lim(임근우),Eung Kook Kim(김응국),Chung Soo Chun(전정수),Jai Hak Lee(이재학),Hyun Shik Son(손현식),Jung Min L 대한외과학회 2002 Annals of Surgical Treatment and Research(ASRT) Vol.63 No.1
전경화,진형민,전정수,Kyong-hwa Jun,M,D,Hyung-min Chin,M,D,and Chung- soo Chun,M,D 대한갑상선-내분비외과학회 2004 The Koreran journal of Endocrine Surgery Vol.4 No.1
Medullary thyroid cancer (MTC) accounts for 5% to 10% of all thyroid cancers, and originates from the parafollicular or C-cells of the thyroid gland. More than 50% of patients present with a thyroid mass and up to 75% of these patients have locoregional lymph node metastasis at the time of diagnosis. The neuroendocrine C-cells of the thyroid gland secrete calcitonin, a relatively accurate tumor marker for MTC. Plasma basal and stimulated calcitonin measurements have been used to screen patients who are at risk of developing MTC and indispensable for the detection of residual MTC after initial surgical treatment. The overall survival rate of patients with MTC is intermediate to that of patients with differentiated thyroid cancer and anaplastic thyroid cancer. Postoperative radioiodine ablation therapy, chemotherapy and radiation therapy are generally ineffective. Surgical resection, therefore, remains the only definite treatment for patients with MTC. Unfortunately, residual MTC as indicated by elevated plasma basal or stimulated calcitonin levels is common even after apparent complete initial surgical resection. We present a case of metastatic MTC in the anterior mediastinum with review of the literatures. (Korean J Endocrine Surg 2003;4:55-58)