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Christopher J.Davies,박용호,Yi Seok Joo,Joo Youn Park,Jin San Moon,So Hyun Kim,Nam Hoon Kwon,Jong Sam Ahn,William C.Davis 대한수의학회 2004 Journal of Veterinary Science Vol.5 No.1
Bovine mastitis is an infectious disease with a major economic influence on the dairy industry worldwide. Many factors such as environment, pathogen, and host affect susceptibility or resistance of an individual cow to bovine mastitis. Recently, there has been considerable interest in defining genetic and immunological markers that could be used to select for improved disease resistance. In this study we have analyzed the lymphocyte subpopulations of mastitis-resistant and susceptible cows using monoclonal antibodies specific for bovine leukocyte differentiation antigens and flow cytometry. We have also used a microarray typing technique to define the bovine leukocyte antigen (BoLA) class I and class II haplotypes associated with resistance or susceptibility to bovine mastitis. A striking finding of the present study is that susceptibility to mastitis was associated with major histocompatibility complex (MHC) haplotypes that have only a single set of DQ genes. The study also revealed that susceptible cows had CD4:CD8 ratios of less than one in both their mammary gland secretions and peripheral blood. These results raise the possibility that the number of DQ genes that a cow has and/or a cow’s CD4:CD8 ratio could be used as indicators of susceptibility to bovine mastitis.
The SAMI Galaxy Survey: global stellar populations on the size–mass plane
Scott, Nicholas,Brough, S.,Croom, Scott M.,Davies, Roger L.,van de Sande, Jesse,Allen, J. T.,Bland-Hawthorn, Joss,Bryant, Julia J.,Cortese, Luca,D'Eugenio, Francesco,Federrath, Christoph,Ferreras, Ign Oxford University Press 2017 MONTHLY NOTICES- ROYAL ASTRONOMICAL SOCIETY Vol.472 No.3
STAR FORMATION ACTIVITY IN THE LONG, FILAMENTARY INFRARED DARK CLOUD G53.2
Kim, Hyun-Jeong,Koo, Bon-Chul,Davis, Christopher J. IOP Publishing 2015 The Astrophysical journal Vol.802 No.1
<P>We present star formation activity in the infrared dark cloud (IRDC) G53.2, a remarkable IRDC located at Galactic coordinates (l, b) similar to (53 degrees.2, 0 degrees.0) based on the census of young stellar object (YSO) candidates. IRDC G53.2 was previously identified as several IRDCs in mid-IR. images, but it is in fact a long (greater than or similar to 45 pc) cloud, well consistent with a CO cloud at v similar to 23 km s(-1) (or at d similar to 1.7 kpc). We present a point-source catalog of IRDC G53.2 that contains similar to 370 sources from our photometry of the Spitzer MIPS 24 mu m data and Galactic Legacy Infrared Mid-Plane Survey Extraordinaire Catalog. The classification of the identified sources based on their spectral index and control field analysis to remove field star contamination reveals that IRDC G53.2 is an active star-forming region with similar to 300 YSO candidates. We compare the YSO classification based on spectral index, mid-IR colors, and the wavelength range used, which results in consistent classification, except for flat-spectrum objects, with some ambiguity between Class I and II. Comparison of the YSO population in IRDC G53.2 with those of other nearby star-forming clusters indicates that they are similar in age; on the other hand, stronger association with mid-IR stellar sources in IRDC G53.2 compared with other IRDCs indicates that IRDC G53.2 is at a later evolutionary stage among IRDCs. Spatial distribution of the YSO candidates in IRDC G53.2 shows a good correlation with (CO)-C-13 column density and far-IR emission, and earlier-class objects tend to be more clustered in the regions with higher density.</P>
Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis
Lauren K. Dunn,Ching-Jen Chen,Davis G. Taylor,Kamilla Esfahani,Brian Brenner,Charles Luo,Thomas J. Buell,Sarah N. Spangler,Avery L. Buchholz,Justin S. Smith,Christopher I. Shaffrey,Edward C. Nemergut 대한척추신경외과학회 2020 Neurospine Vol.17 No.4
Objective: This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain output and transfusion requirements following adult spinal deformity surgery. Methods: One hundred forty-seven patients undergoing posterior instrumented thoracolumbar fusion of ≥3 vertebral levels at a single institution who received low-dose PTXA infusion (0.5–1 mg/kg/hr) for 24 hours were compared to 292 control patients who did not receive PTXA. The cohorts were propensity matched based on age, sex, American Society of Anesthesiologist physical status classification, body mass index, number of surgical levels, revision surgery, operative duration, and total intraoperative TXA dose (n=106 in each group). Primary outcome was 72-hour postoperative drain output. Secondary outcomes were number of allogeneic blood transfusions. Results: There was no significant difference in postoperative drain output in the PTXA group compared to control (660±420 mL vs. 710±490 mL, p=0.46). The PTXA group received significantly more crystalloid (6,100±3,100 mL vs. 4,600±2,400 mL, p<0.001) and red blood cell transfusions postoperatively (median [interquartile range]: 1 [0–2] units vs. 0 [0–1] units; incidence rate ratio [95% confidence interval], 1.6 [1.2–2.2]; p=0.001). Rates of adverse events were comparable between groups. Conclusion: Continuous low-dose PTXA infusion was not associated with reduced drain output after spinal deformity surgery. No difference in thromboembolic incidence was observed. A prospective dose escalation study is warranted to investigate the efficacy of higher dose PTXA.
UNVEILING COMPLEX OUTFLOW STRUCTURE OF UY Aur
PYO, TAE-SOO,HAYASHI, MASAHIKO,BECK, TRACY,DAVIS, CHRISTOPHER J.,TAKAMI, MICHIHIRO The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2
We present [$Fe\;{\small{II}}$] ${\lambda}1.257{\mu}m$ spectra toward the interacting binary UY Aur with 0".14 angular resolution, obtained with the Near infrared Integral Field Spectrograph (NIFS) combined with the adaptive optics system Altair of the GEMINI observatory. In the [$Fe\;{\small{II}}$] emission, UY Aur A (primary) is brighter than UY Aur B (secondary). The blueshifted and redshifted emission between the primary and secondary show a complicated structure. The radial velocities of the [$Fe\;{\small{II}}$] emission features are similar for UY Aur A and B: ${\sim}-100km\;s^{-1}$ and ${\sim}+130km\;s^{-1}$ for the blueshifted and redshifted components, respectively. Considering the morphologies of the [$Fe\;{\small{II}}$] emissions and bipolar outflow context, we concluded that UY Aur A drives fast and widely opening outflows with an opening angle of ${\sim}90^{\circ}$ while UY Aur B has micro collimated jets.