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Challenges and Future of Wireless Capsule Endoscopy
Jean-Christophe Saurin,Nicolas Beneche,Christine Chambon,Mathieu Pioche 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.1
In 2015, capsule endoscopy was introduced as the main investigation method for small bowel mucosal diseases, and its role in colonic diseases has been gradually revealed. Future challenges for capsule endoscopy, besides improvements of image quality and visualization of each part of the small bowel and colonic mucosa, include the development of gastric capsules, the capacity to perform histological examination of the mucosa, and maybe in the future, some capsule endoscopy-driven therapeutics. The aim of this review was to evaluate the clinical demands and feasibility of achieving the aforementioned objectives.
2D-LC Characterization of Comb-Shaped Polymers Using Isotope Effect
Ahn, Seonyoung,Im, Kyuhyun,Chang, Taihyun,Chambon, Pierre,Fernyhough, Christine M. American Chemical Society 2011 ANALYTICAL CHEMISTRY - Vol.83 No.11
<P>A rigorous molecular characterization of comb-shaped polystyrene (PS) was carried out taking advantage of its molecular structure, a normal hydrogenous backbone, and deuterated side chains. Normal phase LC (NPLC) can separate the comb PS species well according to their molecular weight. Nonetheless, it cannot distinguish the backbone from the side chains and the differently structured polymers having a similar molecular weight, e.g, a single backbone comb and a coupled backbone comb with fewer side chains. In contrast to NPLC, the hydrogenous polymer is retained longer than the deuterated counterpart in reversed phase LC (RPLC). When the isotope sensitivity of RPLC is taken advantage of, the comb PS is cross fractionated by NPLC and RPLC, and a two-dimensional mapping with respect to the backbone chain length and the number of branches is fully established.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2011/ancham.2011.83.issue-11/ac2005907/production/images/medium/ac-2011-005907_0004.gif'></P>