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RISS 인기검색어
- 검색키워드
- 저자 : Choi Seulggie (검색결과 14 건)
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Choi, Jin A.,Song, Lina D.,Choi, Seulggie,Park, Sang Min,Kwon, Jin Woo,Jee, Donghyun Williams & Wilkins Co 2019 Medicine Vol.98 No.2
<P><B>Abstract</B></P><P><B>Objectives:</B></P><P>Open-angle glaucoma (OAG) imposes high disease burden in South Korea. Although various effective interventions are available to manage the progression of OAG, there is limited data on the cost-effectiveness of these treatment strategies in South Korea.</P><P><B>Methods:</B></P><P>Using a Markov cohort model, we evaluated the cost-effectiveness of 3 major treatment strategies (medication, laser trabeculoplasty, and trabeculectomy) for South Korean patients with OAG. We projected a 25-year time horizon to study a hypothetical cohort of 10,000 patients of age 40 with mild OAG. The outcome measures were quality-adjusted life-years (QALYs) gained, cost from the societal perspective, and the incremental cost-effectiveness ratio (ICER) of medication, laser trabeculoplasty, and trabeculectomy. Interventions were evaluated at a willingness-to-pay (WTP) threshold of 30,000,000 KRW ($29,152) per QALY gained. Deterministic and probabilistic sensitivity analyses were conducted to address the model uncertainty.</P><P><B>Results:</B></P><P>The mean costs for medication, laser trabeculoplasty, and trabeculectomy were 29,661,740 KRW, 17,34,1342 KRW, and 22,275,438 KRW, respectively. The mean QALYs gained were 15.7, 15.3, and 14.8 for medication, laser trabeculoplasty, and trabeculectomy, respectively. Surgery was strongly dominated because it generated fewer expected QALYs but incurred greater expected cost than laser. The ICER was 30,885,179 KRW per QALY for medication versus laser trabeculoplasty. Laser was cost-effective, however, at a lower WTP threshold of 21,000,000 KRW per QALY gained or below. The results were most sensitive to the progression rates from mild to moderate glaucoma under laser treatment.</P><P><B>Conclusion:</B></P><P>Under the WTP threshold of 30,000,000 KRW per QALY, medication was cost-effective compared with laser trabeculoplasty and trabeculectomy for treating mild OAG in South Korean population. Laser, however, can be a cost-effective alternative in more resource-limited settings.</P>
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Choi, Seulggie,Choi, Jin A.,Kwon, Jin Woo,Park, Sang Min,Jee, Donghyun Wolters Kluwer Health 2018 Medicine Vol.97 No.38
<P><B>Abstract</B></P><P>Due to the rapidly increasing life-expectancy, the prevalence of glaucoma has increased steadily in recent years. We aimed to evaluate the patterns of care and primary treatment strategy patterns in Korea according to glaucoma subtypes to assess the quality of care for glaucoma patients.</P><P>In this serial cross-sectional survey, the claims data from the Korean National Health Insurance Service was used to identify and group glaucoma patients into primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG), other types of glaucoma, and ocular hypertension from 2002 to 2013. Records for outpatient visits, hospitalizations, drug prescriptions, admissions, and surgical interventions were used to determine the patterns of care and identify primary treatment strategies.</P><P>Both the prevalence (0.11% in 2002 to 0.43% in 2013) and incidence rates (0.06% in 2003 to 0.11% in 2013) for glaucoma increased over time. The mean number of outpatient visits increased (4.9–6.0 visits per year), while the proportion of hospitalized patients (2.3–1.0% of patients) and duration of hospital stay (4.5–3.4 days among hospitalized patients) decreased between 2002 and 2013 for patients with POAG. The proportion of patients not being managed by medication or surgery decreased, with POAG and PACG patients receiving medications increasing from 70.9% and 59.2% in 2002 to 88.4% and 63.3% in 2013, respectively. Finally, while the proportion of trabeculectomy decreased (22.2% to 10.0% of surgical procedures in 2002 and 2013, respectively), more patients with PACG have received iridectomy (59.3% to 86.0% of surgical procedures in 2002 and 2013, respectively).</P><P>Between 2002 and 2013, the pattern of care for both patients with POAG and PACG has shifted toward management by outpatient visits and intervention with anti-glaucoma medications in Korea.</P>
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( Sungjun Choi Daein Choi ),( Seulggie Choi ),( Sang Min Park ),( Hyun-sun Yoon ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: There is emerging evidence that rosacea is associated with various systemic diseases. However, its association with cardiovascular disease (CVD) remains controversial. Objectives: We aimed to investigate whether patients with rosacea are at increased risk of developing CVD. Methods: This retrospective cohort study from the Korean National Health Insurance Service-Health Screening Cohort included patients with newly diagnosed rosacea (n=2,681) and age-, sex-, and index year-matched controls without rosacea (n=26,810) between 2003 and 2014. The primary outcome was subsequent CVD including coronary heart disease and stroke. Multivariable Cox regression analyses were used to evaluate adjusted hazard ratios (aHRs) for subsequent CVD adjusted for major risk factors of CVD. Results: Compared to controls, patients with rosacea were more likely to have more comorbidities and were less likely to smoke, consume alcohol, and exercise regularly. Rosacea patients displayed an increased risk for CVD (aHR 1.20, 95% CI 1.03-1.40) and coronary heart disease (aHR 1.29, 95% CI 1.05-1.60) compared to controls. The risk for stroke was not significantly increased (aHR 1.12, 95% CI 0.91-1.37). Conclusion: Patients with rosacea are more likely to develop subsequent CVD adjusted for major CVD risk factors.
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Weight Gain After Smoking Cessation and Cardiovascular Events in Young Adults
Kim, Kyuwoong,Choi, Seulggie,Lee, Gyeongsil,Jeong, Su-Min,Kim, Sung Min,Son, Joung Sik,Yun, Jae Moon,Kim, Yeon-Yong,Park, Seong Yong,Park, Sang Min Elsevier Inc. 2019 Journal of the American College of Cardiology Vol.73 No.25
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Association of waist circumference with muscle and fat mass in adults with a normal body mass index
Gyeongsil Lee,Seulggie Choi,Sang Min Park 한국영양학회 2021 Nutrition Research and Practice Vol.15 No.5
BACKGROUND/OBJECTIVES: We aimed to investigate the association of waist circumference (WC) with body composition among individuals with a normal body mass index (BMI) to distinguish muscle and fat mass, as both affect health differently. SUBJECTS/METHODS: We analyzed dual-energy X-ray absorptiometry data (derived from the Korean National Health and Nutrition Survey, which includes information on fat and lean mass) of 7,493 adults with a normal BMI. Subjects were categorized into four groups of increasing WC. The fourth group was defined as being centrally obese. Each number of subjects are as follows: 1,870, 695, 231, and 39 among men and 3,054, 1,100, 406, and 98 among women. We conducted a sex-stratified linear regression analysis of body composition according to WC group after adjustments for covariates. RESULTS: We observed a positive association of body fat with increasing WC in both men and women (all P for trend: < 0.001). The adjusted mean values for percent body fat with 95% confidence intervals (CIs) according to the four WC groups in ascending order were 17.8 (17.5-18.3), 21.0 (20.6-21.5), 22.1 (21.5-22.8), and 25.1 (24.2-26.1) in men and 29.7 (29.4-30.0), 32.0 (31.6-32.3), 32.9 (32.4-33.4), and 34.7 (33.2-36.1) in women. However, there was an inverted J-shaped association between muscle mass and WC. The fourth group had a higher percent body fat and lower muscle mass than other groups. The adjusted mean values for appendicular skeletal muscle mass index (kg/m2) with 95% CIs according to the four WC groups in ascending order were 7.55 (7.51-7.59), 7.62 (7.56-7.68), 7.65 (7.56-7.74), and 7.22 (7.04-7.41) in men and 5.83 (5.80-5.85), 5.96 (5.92-6.00), 6.03 (5.96-6.10), and 5.88 (5.73-6.03). CONCLUSIONS: There was a positive association between body fat and WC among individuals with normal BMI; conversely there was an inverted J-shaped association between lean body mass and WC. Our findings support the WC measurement should be included in obesity evaluations for adults with a normal BMI.
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Association of Thyroid Status with Health-Related Quality of Life in Korean Older Adults
Minjung Han,Seulggie Choi,Sarang Kim,Ahryoung Ko,Joung Sik Son,Sang Min Park 대한가정의학회 2020 Korean Journal of Family Medicine Vol.41 No.1
Background: While hypothyroidism is associated with negative health effects in the general population, older adults with hypothyroidism have better physical function and comparable rates of depression and cognitive impairment relative to their euthyroid counterparts. The aim of this study was to investigate the association between thyroid status and health-related quality of life in Korean older adults. Methods: In this population-based cross-sectional study, 1,060 adults aged over 60 years were classified by thyroid status into four groups based on their thyroid stimulating hormone (TSH) and free T4 values: overt hypothyroid, subclinical hypothyroid, euthyroid, and subclinical hyperthyroid. The main outcome measure was self-reported health-related quality of life based on the three-level version of the EuroQol-5 dimension (EQ-5D), with utility values of -0.171 and 1.000 corresponding to the worst and best health statuses, respectively. The adjusted means of the EQ-5D three-level version utility values according to thyroid status were determined using a linear regression analysis. Results: In the adjusted analysis, the overt hypothyroid group showed significantly higher EQ-5D three-level version utility values than did the euthyroid group (0.998 vs. 0.908, P=0.000). In the subgroup analyses by sex, the overt hypothyroid group also showed significantly higher EQ-5D three-level version utility values for both men and women than did the euthyroid group (0.998 vs. 0.940, P=0.008; 0.983 vs. 0.882, P=0.001). Conclusion: Asymptomatic Korean older adults aged over 60 years with TSH and free T4 values corresponding to overt hypothyroidism have better health-related quality of life than their euthyroid counterparts.
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( Gyeongsil Lee ),( Seulggie Choi ),( Yoosun Cho ),( Sang Min Park ) 한국임상영양학회 2022 Clinical Nutrition Research Vol.11 No.1
We evaluated the association between obesity status by body mass index (BMI) or waist circumference (WC) and osteoporotic fracture risk. We collected data of 143,673 women with a mean age of 58.5 years without history of osteoporotic fracture from the Korean National Health Insurance Service Cohort. Participants were divided into four groups according to obesity by BMI and WC, normal BMI/WC (BMI 18.5-24.9 kg/㎡ and WC < 85 cm, reference), obese BMI/normal WC (BMI ≥ 25 kg/㎡ and WC < 85 cm), normal BMI/obese WC (BMI < 25 kg/㎡ and WC ≥ 85 cm), and obese BMI/WC (BMI ≥ 25 kg/㎡ and WC < 85cm). Cox proportional hazards regression analyses were performed to obtain hazard ratios (HRs) with 95% confidence intervals (CIs) for the subsequent median 6.0 years, which were adjusted for age, socioeconomic status, lifestyle, morbidity index, and osteoporosis medication. Compared with the normal group, normal BMI/obese WC was associated with a higher osteoporotic fracture risk after multivariable adjustment (HRs [95% CI], 1.13 [1.05-1.21]), and obese BMI/normal WC was associated with a lower osteoporotic fracture risk (0.89 [0.84-0.94]). Obese BMI/normal WC was associated with a lower risk for hip fractures (0.75 [0.57-0.99]). Obese BMI/normal WC was associated with decreased risk of osteoporotic fracture, whereas normal BMI/obese WC was associated with increased risk of osteoporotic fracture compared with the normal group among East Asian women in their late 40s or more.
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