모유영양아와 인공영양아의 피하지방 및 상완위의 성장발육 상태 : 영아의 피하지방 및 상완위 발육상태

최경숙,최혜미,구재옥,임경숙,김주혜,김숙배 동아시아식생활학회 1997 동아시아식생활학회지 Vol.7 No.1

One- to three- month-old infants (n=232) were compared their upper arm cumference and skinfold thickness(triceps, subscapular) by feeding methods in cross-sectional study. There were two groups : breast-fed(BF) and formula-fed groups(FF). As reported previously^(7)), weight, length, head and chest circumferences of these infants were good, and overall growth status was not significantly different by feeding methods, but weight, weight velocity and chest circumference of formula-fed infants were higher than breast-feds at 3 month, significantly. Here, the triceps skinfold thickness of infants at 1, 2, and 3 postpartum months were 7.4, 9.5 and 10.5 ㎜, respectively. The triceps skinfold thickness of breast-fed infants were higher than formula-feds at 1 and 2 postpartum month, but at 3 month, that of formula-fed infants was greater than breast-fed infants, insignificantly. The subscapular skinfold thickness of infants were 6.4, 9.2 and 10.6 ㎜ at 1 to 3 postpartum months, respectively. The upper arm circumference of infants were 11.7, 13.4, 14.3㎝, and the arm muscle diameter were 34.5, 39.3 and 41.7㎝ at one to three postpartum months, respectively. The upper arm circumference of male infants was higher than females at 2, 3 postpartum months. Overall, there were no significant differences between feeding methods in triceps and subscapular skinfold thickness, upper arm circumference and arm muscle diameter. But 3-month-old formula-fed male infants showed bigger significantly in arm circumference than the breast-feds. From this survey, long-term survey on growth and body composition of large scales might be necessary to determine the effect of feeding methods of infants after 3 months and to set proper body composition standard for infant.

Linoleic acid 함량과 ω6/ω3 비율이 침수속박 스트레스에 의한 위궤양의 발병에 미치는 영향

변기원,김창임,최혜미 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.2

This study was designed to determine the effects of linoleic acid contents and ω6/ω3 ratios on the induction of gastric ulcer by water immersion and restraint stress. Sprague-Dawley rats were fed 5 diets containing 7% fat (w/w) for 6 weeks. These diet groups were Lh, Mh, Hh, Mm, Ml, :3 different linoleic acid levels(0.3% of energy(L), 3.5(M), 10(H)) and 3 different ω6/ω3 ratios(11(l), 33(m), 100(h)) with beef tallow, sunflower or fish oil. The Lh group showed a significantly higher ulcer index (UI) than the Mh and Hh groups(p<0.05). At the same linoleic levels, the UI had no significant difference within the ω6/ω3 ratios. The Mh group showed significantly higher(p<0.05) PGE₂ and TBX₂ content than any other group. Pearson's correlation coefficients between UI and PGE₂ and TBX₂ had a negatively significant correlation(p<0.05). Linoleic acid of gastric mucosal phospholipids was reflected by the diet, but was not significantly different. The most significant finding of this study is that not only the absolute amount of linoleic acid, but also the ω6/ω3 ratios are important factors for the prevention of gastric ulcer.

A Study on The Phenolic Content of Potatoes

Hay-mie Choi(최혜미) 한국식품과학회 1976 한국식품과학회지 Vol.8 No.2

1989년도 국민영양조사에 따른 한국인의 식사양상

최혜미,문현경,정해랑,조은영 한국식생활문화학회 1992 韓國食生活文化學會誌 Vol.7 No.3

In this report, we investigated meal patterns by area, age, profession from the data of the Korean National Nutrition Survey which had been carried out in 1989. The proportion of home prepared meal was about 90% at breakfast and dinner, and 46.3% at lunch. People had meals outside of home mainly at lunch(31.1%), and usually ate restaurant meal(17.7%). The proportion of meal skipped was 7.1% at breakfast, 3.9% at lunch, and 1.2% at dinner. At large city, 10.3% of people skipped breakfast, it was the highest proportion among three areas(large city, small city, and rural area). Also, the proportion of meal outside of homes was the highest among all areas. In rural area, home prepared meal was prevalent for all meals. Among all age groups, people between 20 and 49 ate out most frequently. For people between age 16 and 19, meal skipping was frequent for breakfast and dinner, especially, 20.5% of girl skipped breakfast. At lunch, the proportion of meal skipping was the highest in age higher than 50 groups. Among all professions, people in service job skipped lunch and dinner at the highest proportion. Manager and deskworker skipped breakfast by 12.9% and they ate out at lunch by 82.5%.

필수지방산의 결핍이 흰쥐의 뇌발달에 미치는 영향

최혜미,이양자,박현서 생화학분자생물학회 1992 BMB Reports Vol.14 No.2

Sprague Dawley pregnant rats were fed the corn-oil as a EFA-sufficient diet and hydrogenated coconut oil as a EFA-deficient diet during the 14 days of gestation and through lactation. Body and brain weights were measured on pups and the brains were analyzed for DNA, protein, proteolipid protein, cholesterol, phospholipid, and triglyceride. Body weights were significantly low in EFA-deficient group through the 7 week period, but brain weights were significantly depressed before weaning. Brain DNA and protein contents were not affected by EFA deficiency. However, proteolipid protein was significantly lower in the EFA-deficient group than the EFA-sufficient group. Brain cholesterol, phospholipid, and triglyceride were not affected by the EFA deficiency. Fatty acid compositions in the brain were not significantly different between groups but the ratio of n-6/n-3, which is considered to be a biochemical index of EFA deficiency, was much lower in the EFA-deficient pups all through the 7 week period.

일부 농촌지역 ( 충남 탕정 ) 유아원 어린이들의 신체발육 상태와 혈청지질수준과의 연구

최혜미,김복희 한국지질학회 1993 韓國脂質學會誌 Vol.3 No.1

Lipoprotin (a)[Lp(a)] is an LDL-like particle with a large glycoprotein called apo (a) attached to its apoB moiety through disulfide bond. Many case-control studies supported the opinion that plasma Lp(a) levels were associated with premature myocardial infarction. We developed the competitive ELISA method for Lp(a), and using this method we quantitated the Lp(a) concentration in sera of 250 healthy control subjects and 82 patients who underwent coronary angiography for suspected coronary artery disease. Among them 37 patients had no obstruction in the coronary artery (Cath-control group), while the others revealed the presence of coronary artery desease (CAD group). The minimal detectable level of ELISA method for Lp(a) was 4.4 ng/well. The within-assay coefficients of variation (CVs) ranged from 2.69 to 9.92%, and the between-assay CVs ranged from 4.06 to 17.81%. The mean of the analytical recovery was 93.8% and ranged from 81.9 to 106.8%. The mean and median Lp(a) values of the normal Korean population were 0.149 and 0.120 g/L, respectively. The Lp(a) values of the CAD group were significantly higher than those of Cath-control group and normal population (p$lt;0.001, p$lt;0.0001, respectively). A standardized discriminant function coefficient of Lp(a) by mutivariate discriminant statistical analyses indicated that the Lp (a) is an independent risk factor for coronary artery disease in Koreans.

서울시내 일부 저소득층 유아원 어린이들의 신체발육상태와 혈청지질수준

최혜미,김복희,곽충실,이정선,이윤나,고유미 한국지질학회 1994 韓國脂質學會誌 Vol.4 No.2

This research was conducted to ebaluate nutritional status and hyperlipidemia incidence of 59 kindergarten children in low income area in Seoul. The means of percentage of height, weight and weight/height for standards were 100.9%, 96.7% and 97.9%, respectively. Twenty-six percent of children were undernourished and 10% of children were overweighted by Kanawati assessment method from anthropometric data. Fasting blood was collected for serum lipids determination. The means of serum triglyceride level, total-cholesterol level, HDL-cholesterol level, LDL-cholesterol level, atherogenic index and LDL-c/HDL-c were 88.1㎎/㎗, 151.9㎎/㎗, 56.2㎎/㎗, 78.9㎎/㎗, 1.82, and 1.47, respectively. Thirty-two percent of children on serum triglyceride level, 19% on serum total-cholesterol and LDL-cholesterol levels, 18% on serum HDL-cholesterol level were classified in the risk group for cardiovascular disease. It was observed the significant correlations between serum total-cholesterol level and LDL-cholesterol level (r=0.7328,p$lt;0.005), atherogenic index and serum LDL-cholesterol level(r=0.6852,p$lt;0.005), atherogenic index and serum HDL-cholesterol level(r=-0.7707,p$lt;0.005), and atherogenic index and LDL-c/HDL-c(r=0.9599, p$lt;0.005). The body was higher and heavier, the serum LDL-cholesterol level and LDL-c/HDL-c were higher. The atherogenic index was positive correlated with height, sitting height and girth of chest.

남녀 대학생 ( 18 ~ 26 세 ) 의 혈청지질수준에 대한 연구

최혜미,변기원 한국지질학회 1994 韓國脂質學會誌 Vol.4 No.1

A nutritional study was undertaken to determine the serum lipid and lipoprotein levels of 202 college students(99 men, 103 women) aged 18 to 26 years. Fasting blood samples were analyzed for serum total cholesterol(TC), HDL-cholesterol(HDL-C) and triglyceride(TG). Mean values of TC, LDL-C, HDL-C and TG were 172.2, 103.4, 52.3 and 82.3 ㎎/㎗ in men and 182.4, 111.6, 56.3 and 72.5 ㎎/㎗ in women, respectively. Serum lipid and lipoprotein levels were significantly lower in men than in women(p$lt;0.05). There was no significant differences in TG level between men and women but the value was slightly higher in men than in women. Mean values of LDL-C/HDL-C ratio and atherogenic index(AI) were 2.1 and 2.4, respectively, in men and women. Between anthtopometric measurements and serum lipid and lipoprotein levels, correlation did not have statistical significance in men and women but heights were negatively correlated with LDL-C (p$lt;0.05) and BMI was positively correlated with TG in men(p$lt;0.05). Cut-off point of TC in men and women in our study for selecting the subject at moderate and high risk for coronary heart disease according to U.S. NIH was 200 ㎎/㎗ at 75th percentile, 220㎎/㎗ at 90th percentile. By the NCEP(national cholesterol education program) classification, risk group of men and women was 20 and 28% in TC, 12 and 21% in LDL-C, 8 and 4% in HDL-C, respectively. It is recomended that serum lipid and lipoprotein levels continue to track from young adulthood into above the age for the preventive and interventional programs aimed at developing healthy life-styles.

대학생의 체격지수와 식습관의 관계에 관한 연구

최혜미,이윤나 한국식생활문화학회 1994 韓國食生活文化學會誌 Vol.9 No.1

This study was undertaken to investigate the relationship between body mass index and the food habits of college students. For this purpose, 1030 students of Seoul National University were asked to fill out the questionnaires for the food habit and weight control. Actual weights were also measured, on the spot. The results obtained were as follows. 1. Average height and weight were 173.15 ㎝, 63.83 ㎏ for male, and 160.52 ㎝, 52.73 ㎏ for females. The prevalence of underweight, normal and overweight was 32.3, 61.7, 5.5%, respectively. 2. Food habit scores of obese females were lower than normal or underweight females. Male subjects did not show significantly different scores among three groups. 3. Female obese subjects have lower scores than the other groups on the balanced intake of five basic food groups and on the regular meal intakes. Male obese subjects have cholesterol-rich food and animal fat more frequently than normal and underweight males. Male underweight subjects have lower food habit scores on the balanced intake of five basic food groups. 4. Males want to gain weight slightly and females want to lose 4.65 ㎏ weight. All females want to lose weights. Obese males and females want to lose 10 ㎏ weights.

식이 지방 종류와 2 - Acetylaminofluorene 투여가 쥐 연령에 따라 간의 소포체막 변화와 지질과산화물 생성에 미치는 영향

김숙희,최혜미,윤은영 한국지질학회 1992 韓國脂質學會誌 Vol.2 No.1