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간경변증 환자에서 Vibrio cholera non-01, non-0139에 의한 균혈증
조종래,엄태현 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3
We report a case of Vibrio cholerae septicemia in a 64-year-old male patient with liver cirrhosis who complained of fever, diarrhea, and abdominal pain upon admission. The day before the onset of symptoms, he had had seafood. His blood culture was positive for a non-cholera toxin-producing non-O1, non-O139 V. cholerae. The organism was not cultured in the patient's stool specimen, probably because of the empiric antibiotics treatment before blood collection. He recovered by antibiotics, cefotaxime and ciprofloxacin.
Methicillin 내성 포도상 구균의 분리율 및 의료인의 보균율에 대한 연구
조종래,백인기 인제대학교 1994 仁濟醫學 Vol.15 No.3
저자들은 원내감염의 주 원인균 중의 하나인 Methicillin 내성 Staphylococcus aureus(MRSA)를 기준으로 하여, 인제대학교 부속 상계백병원의 원내 감염율을 진단하였고, 의료인군의 비강과 손에서 MRSA의 검출율을 조사하여 보균자를 파악하고 또 원내감염의 전파경로를 추정하여 병원내 감염의 기회를 줄이고자 본 연구를 시행하였다. Methicillin resistent S. aureus(MRSA) is one of main causative bacterias of nosocomial infection. Recently their prevalent rate has continuously increased in Korea, so we have studied the incidence rate of MRSA strains which was isolated from microbiology laboratory in Sanggye Paik hospital between September 1st, 1993 and february 28th, 1994. And we compared the incidence rate of MRSA among various groups ; physicians, nurses, aiders, and medical laboratory technicians. The incidence rate of MRSA among S. aureus was 57% (N=227). Among 87 hospital personnels screened, the nasal cavity and hand carrier rates of MRSA in hospital personnel groups which have had direct contact to patients were 78.6% and 50%, respectively, but the one of MRSA in medical laboratory technician group which has not had direct contact to patients were 0% and 0%, respectively, of all isolated S. aureus. We concluded that hospital personnels were primarily infected by MRSA from patients and spread of MRSA from patients to patients in hospital appeared to have occurred secondarily by direct contact from hospital personnels who were nasal cavity or hand carrier of MRSA.
Yersinia pseudotuberculosis 감염 환자들의 혈청형 및 Plasmid Profile 분석법에 의한 역학조사
조종래,김미애,히로시 후쿠시마,백인기 대한감염협회 1997 감염 Vol.29 No.1
목적: 1996년 봄 서울 동북부의 수락산과 불암산의 옹달샘물을 음용한 후 Yersiniosis가 발병한 환자들로부터 분리된 Y. pseudotuberculosis 3균주와 수락산 휴게소 인근 옹달샘물에서 분리된 1 균주 그리고 그 약수터 근처에서 포획된 등줄쥐에서 분리된 1 균주 사이의 역학 조사를 실시하여 Y. pseudotuberculosis의 감염 경로를 조사 하고자 하였다. 방법: 세 군의 Y. pseudotuberculosis에서 혈청형 검사와 plasmid profile(REAP) 분석검사를 실시하였다. 결과: 세 군의 Y. pseudotuberculosis 균주들의 혈청형과 REAP 유형은 모두 동일한 4b형과 D유형으로 판명되었다. 결론: 이상의 결과로 미루어 볼 때 한국에서는 등줄쥐가 Y. pseudotuberculosis 보유숙주 중의 하나이며 이 균에 감염된 등줄쥐의 배설물이 옹달샘물을 오염시키고 이 물을 음용한 사람들이 Yersiniosis에 이환되는 Y. pseudotuberculosis의 감염경로를 확인하였다. Background: In order to investigate transmission route of Yersinia pseudo-tuberculosis infection in Korea, we tried epidemiological study among human strains, mountain spring water strain and wild mouse strain which were isolated in north eastern area of Seoul on spring in 1996. Methods: Plasmid profile (Restriction Endonuclease Analysis of Virulence Plasmid DNA analysis: REAP) assay in addition to serotyping were performed among human strains, mountain spring water strain and wild mouse strains. Results: All isolates were the same O serotype of 4b and the same REAP pattern of type D (Fukushima II. et al., J. Clin. Microbiol. 32:1410-3, 1994). Conclusion: These results suggested that wild mice (especially Apodemus agrarius) were one of main reservoir of Y. pseudotuberculosis in Korea and their fecal material might contaminate mountain spring water. Most of human infections of Y. pseudotuberculosis were originated from drinking of contaminated mountain spring waters in Korea.
한국인의 정상 대조군 및 위장관 환자군에서 Helicobacter pylori 항체에 대한 연구
조종래,백인기,신원창 대한감염학회 1996 감염 Vol.28 No.1
목적 :H. pylori에 대한 다양한 진단 방법 가운데 비교적 간편하면서 혈청학적으로 진단이 가능한 면역 항체 검사법을 이용하여 상부 위장관 질환과 H. pylori 항체와의 관계를 조사하고자 하였다. 방법 : 위내시경으로 확인된 대조군, 위염군, 및 위궤양군에서 효소 항체 측정법으로 H. pylori에 대한 항체 Ig G, Ig A, Ig M의 양성율과 흡광도값을 구하여 각 항체와 질환과의 유의성을 검토하였다. 결과 : 1) 대조군, 위염군 및 위궤양군에서 측정한 H. pylori Ig G, A 및 M 항체 양성율은 각 군 사이에 유의한 차이가 없었다. 2) 대조군, 위염군, 및 위궤양군의 H. pylori에 대한 Ig G, A 및 M 항체가는 각 군 사이에 통계적 유의성이 없었다. 결론 : H. pylori에 대한 항체 Ig G, A 및 M은 위염이나 위궤양을 가진 군과 위 내시경 검사에서 정상 소견을 보인 대조군 사이에서 통계적 유의성이 없었다. Background : Helicobacter pylori(H. pylori) antibody test by enzyme immunoassay is relatively simple and easy diagnostic tool, compared with traditional culture which is technically difficult, and other methods. However, the diagnostic significance of the antibody test has not been evaluated in Korea. Methods : We tried to evaluate seropositive rate and antibody titers for H. pylori using ELISA test in 23 of controls, 12 of chronic gastritis and 44 cases of chronic gastric ulcer groups, who were diagnosed by gastrofiberoscope. Results : There were no statistically significant differences(p>0.5) in H. pylori antibody positivity rate and antibody titers among three groups. Conclusion : This study suggests that H. pylroi antibody test alone should not be used in order to correlate H. pylori infection with gastrointestinal disorders in routine health check-up, because there are high seropositive rate of H. pylori antibodies in normal adult population in Korea. Further study for ELISA test would be warranted to evaluate the significance of the antibody test in Korea.
mesopuff Ⅱ 모델을 이용한 서울시 SO₂배출량이 주변지역 대기질에 미치는 영향 분석
조창래,이종범 江原大學校 附設 環境硏究所 1999 環境硏究 Vol.16 No.-
To study the influences of the emission sources during June 13~15 1997 in Seoul, MESOPUFF Ⅱ model has been used. The MESOPUFF Ⅱ model includes terrain effects, chemical transformation and removal processes. Data of 20 surface meteorological stations and the upper air station on mid-west area in Korea were used as a DWM(Diagnostic Wind Model) input data. This model is likely to be applicable because the predicted SO₂concentration was well matched with measured SO₂concentration in Seoul and Kyonggido. In generally air pollutants in Seoul have major influence on the other cities but the result of modeling appeared also air pollutants of the other cities influence on Seoul. Finally, in the case of calculating the air quality by diffusion model, the influences of air pollutants emitted in metropolitan area as well as the emission rate in modeling area should be considered.
터보機械의 回轉翼이 그 末端付近에서 받는 壓力과 末端틈과의 關係
趙江來,金鍾億,申鉉佑 연세대학교 대학원 1974 延世論叢 Vol.11 No.1
Tip clearance in rotor blade takes part in the stage efficiency of a turbomachinery. Authors attempt to survey the pressure field around a rotor blade tip. In general tip clearance being not so create, the pressue magnitude around a blade tip may be considered to be transmitted on a casing wall without any pressure attenuation. Under such assumption the pressure measurements are performed on the casing wall, varing the breadth of tip clearance, tip velocity and blade angle. As the experimental results, it is concluded that the pressure difference on the pressure and suction surfaces of a blade tip appears large in a certain clearance region, hence there is a optimum clearance on the lift of a blade tip portion.