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Anti-inflammatory and Anti-allergic Effects of Lycii Fructus Extract
Lee Young-Sun,Lee Geum-Hong,Kwon Young-Kyu,Lee In-Kyung,Xue Charlie-C.L.,Li Chun-G,Lee Se-Young,Shin Sang-Woo The Physiological Society of Korean Medicine 2005 동의생리병리학회지 Vol.19 No.5
Lycii Fructus (LF) has been reported to possess various biological activities. In this study, we investigated the anti-inflammatory and anti-allergic effects of LF extract in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells and rat peritoneal mast cells(RPMC). LF extract inhibited NO production and the expressions of inducible NO synthase (iNOS) mRNA and enzyme protein, determined by Griess reactions, RT-PCR and Western blotting, respectively, in LPS-stimulated RAW 264.7 macrophages cells. LF extract significantly inhibited histamine release in compound48/80 stimulated rat peritoneal mast cells compared with the compound48/80 only treated cells. It is suggested that the LF extract can improve the inflammation status that involves the histamine release.
Chinese Herbs for Memory Disorders: A Review and Systematic Analysis of Classical Herbal Literature
Brian H. May,Chuanjian Lu,Yubo Lu,Anthony L. Zhang,Charlie C.L. Xue 사단법인약침학회 2013 Journal of Acupuncture & Meridian Studies Vol.6 No.1
Text mining and other literature-based investigations can assist in identifying natural products for experimental and clinical research. This article details a method for systematically analyzing data derived from the classical Chinese medical literature. We present the results of electronic searches of Zhong Hua Yi Dian (“Encyclopaedia of Traditional Chinese Medicine”), a CD of 1000 premodern (before 1950) medical books, for single herbs, and other natural products used for dementia, memory disorders, and memory improvement. This review explores how the terminology for these disorders has changed over time and which herbs have been used more or less frequently, and compares the results from the premodern literature with the herbs indexed for memory disorders in a modern pharmacopoeia. The searches located 731 citations deriving from 127 different books written between ca. 188 AD and ca. 1920. Of the 110 different natural products identified, those most frequently cited for forgetfulness were yuan zhi (Polygala tenuifolia),fu shen (Poria cocos), and chang pu (Acorus spp.), all of which have been cited repeatedly over the past 1800 years and appear among the 31 herbs indexed in a modern pharmacopoeia. By providing a complete, hierarchically organized list of herbs for a specific disorder, this approach can assist researchers in selecting herbs for research.