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      • KCI등재

        RIA 기반 개인화 검색을 위한 Widget 응용의 구현

        박차라(Chara Park),임태수(Taesoo Lim),이우기(Wookey Lee) 한국정보과학회 2007 정보과학회 컴퓨팅의 실제 논문지 Vol.13 No.6

        쉽고 유연한 조작과 역동적인 화면구성에 초점을 맞춘 인터넷서비스 맞춤기술인 RIA(Rich Internet Application)기술들은 웹2.0기술 중 사용자 편의성을 강조한 차세대 UI기술로 기대되고 있다. 본 논문은 평면적이고 순차적인 방법의 고급검색을 동적UI로 구현하고 사용자가 개인화 검색정보를 저장해서 검색에 활용할 수 있도록 구현하였다. 또한 사용자중심의 키워드 선호도를 통해 기존 웹 검색보다 개인화된 검색 결과물을 발견할 수 있는 검색구조를 설계하였다. 본 연구는 RIA 기술을 활용한 개인화 검색 관리자의 적용을 통해 검색된 페이지양의 감소를 입증하여 사용자에게 더욱 정제된 데이타를 제공하며 결론적으로 사용자들이 더욱 유연하고 편리한 방법으로 개인화된 웹 검색을 이용할 수 있음을 보였다. Rich Internet Application(RIA) is one of the Web 2.0 technologies and is expected to be a next generation user interface technique which allows flexible and dynamic manipulation for Web searches. This paper addresses a personalization mechanism for advanced Web search using RIA for abundant user interactions. We devised a dynamic and graphical user interface instead of previous text-based searches and a client side application for storing personal preference information. In this research, we implemented the graphical personalized search manager using Yahoo web search API and widget, and demonstrated its effectiveness by performing some experiments with various query terms and representative predicates.

      • RIA 기술을 활용한 개인화된 웹 검색

        박차라(Chara Park),임태수(Taesoo Rim),이우기(Wookey Lee) 한국정보과학회 2007 한국정보과학회 학술발표논문집 Vol.34 No.1A

        쉽고 유연한 조작과 다양하고 역동적인 화면구성에 초점을 맞춘 인터넷서비스 맞춤기술인 RIA(Rich Internet Application)기술들은 웹2.0기술 중 사용자 편의성을 강조한 차세대 UI기술로 기대되고 있다. 본 논문은 평면적이고 순차적인 방법의 고급검색을 동적UI로 구현하고 사용자가 개인화 검색정보를 저장해서 검색에 활용할 수 있도록 구현하였다. 또한 사용자중심의 키워드 선호도를 통해 기존 웹 검색보다 개인화된 검색 결과물을 발견할 수 있는 검색구조를 설계하였다. 본 연구는 RIA 기술을 활용한 개인화 검색 관리자의 적용을 통해 검색된 페이지양의 감소를 입증하여 사용자에게 더욱 정제된 데이터를 제공하며 결론적으로 사용자들이 더욱 유연하고 편리한 방법으로 개인화된 웹 검색을 이용할 수 있음을 보였다.

      • KCI등재

        Loss of LKB1 Protein Expression Correlates with Increased Risk of Recurrence and Death in Patients with Resected, Stage II or III Colon Cancer

        Maria Sfakianaki,Chara Papadaki,Maria Tzardi,Maria Trypaki,Sardar Alam,Eleni D. Lagoudaki,Ippokratis Messaritakis,Odysseas Zoras,Dimitris Mavroudis,Vassilis Georgoulias,John Souglakos 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4

        Purpose The purpose of this study was to investigate the prognostic significance of liver kinase b1 (LKB1) loss in patients with operable colon cancer (CC). Materials and Methods Two hundred sixty-two specimens from consecutive patients with stage III or high-risk stage II CC, who underwent surgical resection with curative intent and received adjuvant chemotherapy with fluoropyrimidine and oxaliplatin, were analyzed for LKB1 protein expression loss, by immunohistochemistry as well as for KRAS exon 2 and BRAFV600E mutations by Sanger sequencing and TS, ERCC1, MYC, and NEDD9 mRNA expression by real-time quantitative reverse transcription polymerase chain reaction. Results LKB1 expression loss was observed in 117 patients (44.7%) and correlated with right-sided located primaries (p=0.032), and pericolic lymph nodes involvement (p=0.003), BRAFV600E mutations (p=0.024), and TS mRNA expression (p=0.041). Patients with LKB1 expression loss experienced significantly lower disease-free survival (DFS) (hazard ratio [HR], 1.287; 95% confidence interval [CI], 1.093 to 1.654; p=0.021) and overall survival (OS) (HR, 1.541; 95% CI, 1.197 to 1.932; p=0.002), compared to patients with LKB1 expressing tumors. Multivariate analysis revealed LKB1 expression loss as independent prognostic factor for both decreased DFS (HR, 1.217; 95% CI, 1.074 to 1.812; p=0.034) and decreased OS (HR, 1.467; 95% CI, 1.226 to 2.122; p=0.019). Conclusion Loss of tumoral LKB1 protein expression, constitutes an adverse prognostic factor in patients with operable CC.

      • KCI등재

        Safety of a New Synbiotic Starter Formula

        Yvan Vandenplas,Antonis Analitis,Chara Tziouvara,Athina Kountzoglou,Anastasia Drakou,Manos Tsouvalas,Antigoni Mavroudi,Ioannis Xinias 대한소아소화기영양학회 2017 Pediatric gastroenterology, hepatology & nutrition Vol.20 No.3

        Purpose: Breastfeeding is the best way to feed all infants, but not all infants can be (exclusively) breastfed. Cow’smilk based infant formula is the second choice infant feeding.Methods: The safety of a new synbiotic infant formula, supplemented with Bifidobacterium lactis and fructo-oligo-saccharides, with lactose and a whey/casein 60/40 protein ratio was tested in 280 infants during 3 months.Results: The median age of the infants at inclusion was 0.89 months. Weight evolution was in accordance with the World Health Organization growth charts for exclusive breastfed infants. The evolution of all anthropometric parame-ters (weight-for-length z score and body mass index-for-age z score) was within the normal range. The incidence of functional constipation (3.2%), daily regurgitation (10.9%), infantile crying and colic (10.5%) were all significantly lower than the reported median prevalence for a similar age according to literature (median value of 7.8% for functional constipation, 26.7% for regurgitation, 17.7% for infantile colic).Conclusion: The new synbiotic infant starter formula was safe, resulted in normal growth and was well tolerated. Functional gastro-intestinal manifestations (functional constipation, regurgitation and colic) were significantly lower than reported in literature. Synbiotics (Bifidobacterium lactis and fructo-oligosaccharides) in cow’s milk based infant formula bring the second choice infant feeding, formula, closer to the golden standard, exclusive breastfeeding.

      • SCOPUSKCI등재

        Influence of Shiftwork on Greek Nursing Personnel

        Korompeli, Anna,Muurlink, Olav,Tzavara, Chara,Velonakis, Emmanouel,Lemonidou, Chrysoula,Sourtzi, Panayota Occupational Safety and Health Research Institute 2014 Safety and health at work Vol.5 No.2

        Background: The aim of this study was to investigate the burden experienced by nursing personnel working irregular shifts in Greece and to conduct the first test of a Greek version of the Standard Shiftwork Index (SSI). Methods: A cross-sectional survey was carried out. The SSI was completed by 365 nurses and nursing assistants working shifts, including nights. Results: Female nursing personnel and those suffering from a chronic disease were most affected by working rotating shifts as they had elevated scores on the majority of the SSI scales, such as sleep, chronic fatigue, digestive and cardiovascular problems, general health questionnaire, cognitive and somatic anxiety, shift time satisfaction, engagement and disengagement strategies, languidity, flexibility, and neurotisicm. Nurses with longer working experience and those with family responsibilities also scored higher on some of the SSI scales, such as the sleep, shift time satisfaction, social and domestic disruption, disengagement strategies, morningness, and languidity scales. Conclusion: Shiftwork affects female nurses, those with chronic disease, older age, and domestic responsibilities more severely. Therefore management should take these factors into account when designing work schedules to alleviate the burden caused by shiftwork.

      • SCOPUSKCI등재

        Safety of a New Synbiotic Starter Formula

        Vandenplas, Yvan,Analitis, Antonis,Tziouvara, Chara,Kountzoglou, Athina,Drakou, Anastasia,Tsouvalas, Manos,Mavroudi, Antigoni,Xinias, Ioannis The Korean Society of Pediatric Gastroenterology 2017 Pediatric gastroenterology, hepatology & nutrition Vol.20 No.3

        Purpose: Breastfeeding is the best way to feed all infants, but not all infants can be (exclusively) breastfed. Cow's milk based infant formula is the second choice infant feeding. Methods: The safety of a new synbiotic infant formula, supplemented with Bifidobacterium lactis and fructo-oligosaccharides, with lactose and a whey/casein 60/40 protein ratio was tested in 280 infants during 3 months. Results: The median age of the infants at inclusion was 0.89 months. Weight evolution was in accordance with the World Health Organization growth charts for exclusive breastfed infants. The evolution of all anthropometric parameters (weight-for-length z score and body mass index-for-age z score) was within the normal range. The incidence of functional constipation (3.2%), daily regurgitation (10.9%), infantile crying and colic (10.5%) were all significantly lower than the reported median prevalence for a similar age according to literature (median value of 7.8% for functional constipation, 26.7% for regurgitation, 17.7% for infantile colic). Conclusion: The new synbiotic infant starter formula was safe, resulted in normal growth and was well tolerated. Functional gastro-intestinal manifestations (functional constipation, regurgitation and colic) were significantly lower than reported in literature. Synbiotics (Bifidobacterium lactis and fructo-oligosaccharides) in cow's milk based infant formula bring the second choice infant feeding, formula, closer to the golden standard, exclusive breastfeeding.

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