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RISS 인기검색어
- 검색키워드
- 저자 : Carol S. Johnston (검색결과 2 건)
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Carol S. Johnston,Andrea M. White,Shannon M. Kent 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.1
Vinegar (VIN) ingestion at mealtime reduces postprandial glycemia and may benefit individuals with diabetes;hence, the medicinal use of VIN has increased in recent years. This study examined the safety and tolerance of medicinallyingested VIN in type 2 diabetics. Participants (n . 27) were stratified by gender, age, and body mass and randomized intothree groups: commercial VIN pills (the reference treatment [REF] (30 mg of acetic acid daily), pickles (PCK) (. 1,400 mgof acetic acid daily), or VIN (2,800 mg of acetic acid daily). Participants continued their normal eating habits during the 12-week trial. At baseline and weeks 6 and 12, fasting blood and urine samples were collected, and adverse changes in bowelmovements, frequency of burping or flatulence, and episodes of acid reflux were recorded. Reporting frequency for adverseevents did not vary significantly by group during the trial; however, 5056% of PCK and VIN participants reported at leastone treatment-emergent adverse event at week 6 as compared to 11% of REF participants (P. .110). Urinary pH was sig-nificantly reduced in VIN participants at week 12 as compared to the other groups (. 9% vs. . 3% and . 2% for the PCKand REF groups, respectively, P. .023). At week 6 there was a tendency for aspartate aminotransferase concentrations toincrease in the VIN group as compared to the other groups (. 17% vs. . 8% and . 8% for VIN, PCK, and REF, respectively;P. .090). These data indicate that chronic VIN ingestion may influence hepatic function and metabolic pathways aside fromglucose metabolism.
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Evidence That Daily Vinegar Ingestion May Contribute to Erosive Tooth Wear in Adults
Summer Anderson,Lisa A. Gonzalez,Paniz Jasbi,Carol S. Johnston 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.8
Vinegar ingestion at mealtime is gaining popularity for its antiglycemic effects; however, it is among the most acidic consumable substances. This study examined tooth wear in healthy adults participating in an 8-week randomized trial examining the effect of daily vinegar ingestion on insulin sensitivity and visceral fat reduction. Twice daily participants consumed a vinegar drink (two tablespoons vinegar in a cup of water; 3.6 g acetic acid) or a commercial vinegar pill (control, 0.045 g acetic acid) at mealtime. Participants were screened for dental erosion using the basic erosive wear examination (BEWE) by a blinded registered dental hygienist at trial baseline and week 8. Mean BEWE scores did not change in the control group but increased 18% in the vinegar group over the 8-week study (P = .038). Given the current popularity of vinegar as a medicinal agent, practitioners should caution patients who utilize this strategy on the possibility of erosive tooth wear. Trial registration: This trial was registered at ClinicalTrials.gov (NCT03577834) on July 5, 2018 and the institutional review board at Arizona State University provided ethical approval (STUDY00005418).
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