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Alachlor Use and Cancer Incidence in the Agricultural Health Study: An Updated Analysis
Lerro, C. C.,Andreotti, G.,Koutros, S.,Lee, W. J.,Hofmann, J. N.,Sandler, D. P.,Parks, C. G.,Blair, A.,Lubin, J. H.,Beane Freeman, L. E. U.S. Dept. of Health, Education, and Welfare, Publ 2018 Journal of the National Cancer Institute Vol.110 No.9
J.A. Morán Meza,J. Polesel-Maris,C. Lubin,F. Thoyer,A. Makky,A. Ouerghi,J. Cousty 한국물리학회 2015 Current Applied Physics Vol.15 No.9
Sharp Pt/Ir tips have been reproducibly etched by an electrochemical process using an inverse geometry of an electrochemical cell and a dedicated electronic device which allows us to control the applied voltages waveform and the intensity of the etching current. Conductive tips with a radius smaller than 10 nm were routinely produced as shown by field emission measurements through Fowler-Nordheim plots. These etched tips were then fixed on a quartz tuning fork force sensor working in a qPlus configuration to check their performances for both scanning tunneling microscopy (STM) and atomic force microscopy (AFM) imaging. Their sharpness and conductivity are evidenced by the resolution achieved in STM and AFM images obtained of epitaxial graphene on 6H-SiC(0001) surface. The structure of an epitaxial graphene layer thermally grown on the 6H-SiC(0001) (6 √3 × 6 √3 ) R30˚ reconstructed surface, was successfully imaged at room temperature with STM, dynamic STM and by frequency modulated AFM.
Cancer Incidence among Pesticide Applicators Exposed to Alachlor in the Agricultural Health Study
Lee, Won Jin,Hoppin, Jane A.,Blair, Aaron,Lubin, Jay H.,Dosemeci, Mustafa,Sandler, Dale P.,Alavanja, Michael C. R. Oxford University Press 2004 American Journal of Epidemiology Vol.159 No.4
<P> The authors evaluated the incidence of cancer among pesticide applicators with exposure to alachlor in the Agricultural Health Study, a prospective cohort study of licensed pesticide applicators in Iowa and North Carolina. A total of 49,980 pesticide applicators are included in this analysis; 26,510 applicators (53%) reported use of alachlor on the enrollment questionnaire. Detailed pesticide exposure and other information were obtained from a self-administered questionnaire completed at the time of enrollment (1993–1997). Poisson regression analysis was used to evaluate the exposure-response relations between alachlor and cancer incidence controlled for the effects of potential confounding factors. A total of 1,466 incident malignant neoplasms were diagnosed during the study period, 1993–2000. Among alachlor-exposed applicators, the authors found a significant increasing trend for incidence of all lymphohematopoietic cancers associated with lifetime exposure-days (<I>p</I> for trend = 0.02) and intensity-weighted exposure-days (<I>p</I> for trend = 0.03) to alachlor. The risks of leukemia (rate ratio = 2.83, 95% confidence interval: 0.74, 10.9) and multiple myeloma (rate ratio = 5.66, 95% confidence interval: 0.70, 45.7) were increased among applicators in the highest alachlor exposure category. Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study.</P>