http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Tae-Yang Noh,Beom-Hee Lee,Byeong-Mok Park1,Ah-Ran Cha,Hee-Chul Yang 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
Nuclear power plants in Korea stores approximately 3,800 drums of paraffin solidification products. Due to the lack of homogeneity, these solidification products are not allowed to be disposed of. There is therefore a need for the separation of paraffin from the solidification products. This work developed an equipment for a selective separation of paraffin from the solidification product using the vacuum evaporation and condensational recovery method in a closed system. The equipment mainly consists of a vacuum evaporator and a condensational deposition recovery chamber. Nonisothermal vacuum TGAs, kinetic analyses and kinetic predictions were conducted to set appropriate operation conditions. Its basic operability under the established conditions was first confirmed using pure paraffin solid. Simulated paraffin solidification product fixing dried boric acid waste including nonradioactive Co and Cs were then fabricated and tested for the capability of selective separation of paraffin from the simulated waste. Paraffin was selectively separated without entertainment of Co and Cs. It was confirmed that the developed equipment could separate and recover paraffin in the form of nonradioactive waste.
Oh, Sun-Hee,Park, Se-Min,Park, Jong-Sook,Jang, An-Soo,Lee, Yong-Mok,Uh, Soo-Taek,Kim, Young Hoon,Choi, In-Seon,Kim, Mi-Kyeong,Park, Byeong Lae,Shin, Hyoung-Doo,Park, Choon-Sik The Korean Academy of Asthma, Allergy and Clinical 2009 Allergy, Asthma & Immunology Research Vol.1 No.1
<P><B>Purpose</B></P><P>Peroxisome proliferator-activated receptors (PPARs) are transcriptional factors activated by ligands of the nuclear hormone receptor superfamily. The activation of PPARγ regulates inflammation by downregulating the production of Th2 type cytokines and eosinophil function. In addition, a range of natural substances, including arachidonate pathway metabolites such as 15-hydroxyeicosatetranoic acid (15-HETE), strongly promote <I>PPARG</I> expression. Therefore, genetic variants of the <I>PPARG</I> gene may be associated with the development of aspirin-intolerant asthma (AIA). We investigated the relationship between single nucleotide polymorphism (SNP) of the <I>PPARG</I> gene and AIA.</P><P><B>Methods</B></P><P>Based on the results of an oral aspirin challenge, asthmatics (n=403) were categorized into two groups: those with a decrease in FEV<SUB>1</SUB> of 15% or greater (AIA) or less than 15% (aspirin-tolerant asthma, ATA). We genotyped two single nucleotide polymorphisms in the <I>PPARG</I> gene from Korean asthmatics and normal controls (n=449): +<I>34C>G</I> (Pro12Ala) and +<I>82466C>T</I> (His449His).</P><P><B>Results</B></P><P>Logistic regression analysis showed that +<I>82466C>T</I> and haplotype 1 (CC) were associated with the development of aspirin hypersensitivity in asthmatics (<I>P</I>=0.04). The frequency of the rare allele of +<I>82466C>T</I> was significantly higher in AIA patients than in ATA patients in the recessive model [<I>P</I>=0.04, OR=3.97 (1.08-14.53)]. In addition, the frequency of <I>PPARG</I> haplotype 1 was significantly lower in AIA patients than in ATA patients in the dominant model (OR=0.25, <I>P</I>=0.04).</P><P><B>Conclusions</B></P><P>The +<I>82466C>T</I> polymorphism and haplotype 1 of the <I>PPARG</I> gene may be linked to increased risk for aspirin hypersensitivity in asthma.</P>
Young Mok Park,Hyung Il Seo,Byeong Gwan Noh,Suk Kim,Seung Baek Hong,Nam Kyung Lee,Dong Uk Kim,Sung Yong Han 한국간담췌외과학회 2023 Annals of hepato-biliary-pancreatic surgery Vol.27 No.4
Backgrounds/Aims: In 2019, the grading and staging system for neuroendocrine neoplasms (NENs) was significantly changed. In this study, we report the clinicopathological characteristics and surgical outcomes of patients with extrahepatic biliary NENs who underwent curative resection with or without adjuvant treatment. Methods: We retrospectively reviewed a database of 16 patients who developed NENs, neuroendocrine carcinoma (NEC), and mixed endocrine non-endocrine neoplasms (MiNENs) after curative resection. Among them, eight patients had ampulla of Vater (AoV) tumors, and eight patients had non-AoV tumors. Results: G1 and G2 were more frequently observed in the AoV group than in the non-AoV group (12.5% and 62.5%, respectively). In contrast, NEC and MiNEN were more common in the non-AoV group (50.0%). High Ki-67 index (> 20%) and perineural invasion (PNI) were more frequently observed in the non-AoV group. Advanced age (> 65 years), mitotic count > 20 per 2 mm2, and Ki-67 index > 20% were strongly correlated with patient survival (p = 0.018, 0.009, and 0.044, respectively). Advanced age (> 65 years) and mitotic count > 20 per 2 mm2 were significantly correlated with disease recurrence (p = 0.033 and 0.010, respectively). Conclusions: AoV and non-AoV tumors had significant differences in the histologic grade, Ki67, and PNI. Patients with non-AoV tumors had an increased risk for survival and recurrence than those in the AoV group. For extrahepatic biliary NENs, early detection of tumors, adequate surgery, and aggressive adjuvant treatment for high-risk patients are important to achieve long-term survival and prevent disease recurrence.