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      • KCI등재

        ZIF-8 Modified Nanofiber Composite Window Screen for Efficient Indoor PM2.5 and Formaldehyde Removal

        Fan Liu,Tong Lu,Wanjun Bu,Hewei Xiang,Junjie Yang,Junli Li,Xu Zhao,Weili Shao,Qingqing Ni,Jianxin He 한국섬유공학회 2022 Fibers and polymers Vol.23 No.8

        Because people spend a lot of time indoors every day, the presence of particulate matter with a diameter less than2.5 μm (PM2.5) and volatile organic molecular substances in indoor air adversely affect public health. These toxic compoundscan be removed from the air using high-efficiency air-filter materials with adsorption capacity. Metal-organic frameworks(MOFs) are among the most suitable materials for air purification as they are synthetic porous materials with excellentadsorption ability. In this study, the zeolitic imidazolate framework-8 (ZIF-8) is uniformly grown on the surface ofpolyacrylonitrile (PAN) nanofibers using an in situ growth method to prepare ZIF-8@PAN nanofiber composite membranes. The nanofiber composite membrane effectively removes PM2.5 and formaldehyde from the air. After loading the optimalamount of ZIF-8, the filtration efficiency of the nanofiber membrane for salt aerosol with a diameter of 0.3 μm increases from90.3 % to 96.9 %, and the removal rate of formaldehyde becomes 98 % within 20 min in the enclosed space of the laboratory. Moreover, after five repeated tests, the formaldehyde adsorption rate remains above 80 %. In addition, ZIF-8@PANnanofiber membranes are used to fabricate anti-haze window screens, which have great potential to improve indoor airquality and mitigate related health risks.

      • Clinical and Prognostic Significance of SOX11 in Breast Cancer

        Liu, Dao-Tong,Peng-Zhao, Peng-Zhao,Han, Jing-Yan,Lin, Fan-Zhong,Bu, Xian-Min,Xu, Qing-Xia Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13

        Recently, the transcription factor SOX11 has gained extensive attention as a diagnostic marker in a series of cancers. However, to date, the possible roles of SOX11 in breast cancer has not been investigated. In this study, immunohistochemical staining for SOX11 was performed for 116 cases of breast cancer. Nuclear SOX11 was observed in 42 (36.2%) and cytoplasmic SOX11 in 52 (44.8%) of breast cancer samples. Moreover, high expression of cytoplasmic and nuclear SOX11 was associated with clinicopathological factors, including earlier tumor grade, absence of lymph node metastasis and smaller tumor size. Kaplan-Meier survival curves demonstrated high nuclear SOX11 expression to be associated with more prolonged overall survival than those with low expression and it could be an independent predictor of survival for breast cancer patients. It is worthwhile to note that cytoplasmic SOX11 was not correlated with prognosis of breast cancer patients. These data suggest the possibility that nuclear SOX11 could be as a potential target for breast cancer therapy.

      • KCI등재

        Structural optimization approach for specially shaped composite tank in spacecrafts

        Ren Mingfa,Bu Fanzi,Tong Li 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.4

        This study proposes an optimized approach of designing in which a model specially shaped composite tank for spacecrafts is built byapplying finite element analysis. The composite layers are preliminarily designed by combining quasi-network design method with numericalsimulation, which determines the ratio between the angle and the thickness of layers as the initial value of the optimized design. By adopting an adaptive simulated annealing algorithm, the angles and the numbers of layers at each angle are optimized to minimize theweight of structure. Based on this, the stacking sequence of composite layers is formulated according to the number of layers in the optimizedstructure by applying the enumeration method and combining the general design parameters. Numerical simulation is finallyadopted to calculate the buckling limit of tanks in different designing methods. This study takes a composite tank with a cone-shapedcylinder body as example, in which ellipsoid head section and outer wall plate are selected as the object to validate this method. Theresult shows that the quasi-network design method can improve the design quality of composite material layer in tanks with complexpreliminarily loading conditions. The adaptive simulated annealing algorithm can reduce the initial design weight by 30%, which effectivelyprobes the global optimal solution and optimizes the weight of structure. It can be therefore proved that, this optimization methodis capable of designing and optimizing specially shaped composite tanks with complex loading conditions.

      • SCIESCOPUSKCI등재

        On Optimizing Route Discovery of Topology-based On-demand Routing Protocols for Ad Hoc Networks

        Seet, Boon-Chong,Lee, Bu-Sung,Lau, Chiew-Tong The Korea Institute of Information and Commucation 2003 Journal of communications and networks Vol.5 No.3

        One of the major issues in current on-demand routing protocols for ad hoc networks is the high resource consumed by route discovery traffic. In these protocols, flooding is typically used by the source to broadcast a route request (RREQ) packet in search of a route to the destination. Such network-wide flooding potentially disturbs many nodes unnecessarily by querying more nodes than is actually necessary, leading to rapid exhaustion of valuable network resources such as wireless bandwidth and battery power. In this paper, a simple optimization technique for efficient route discovery is proposed. The technique proposed herein is location-based and can be used in conjunction with the existing Location-Aided Routing (LAR) scheme to further reduce the route discovery overhead. A unique feature of our technique not found in LAR and most other protocols is the selective use of unicast instead of broadcast for route request/query transmission made possible by a novel reuse of routing and location information. We refer to this new optimization as the UNIQUE (UNIcast QUEry) technique. This paper studies the efficacy of UNIQUE by applying it to the route discovery of the Dynamic Source Routing (DSR) protocol. In addition, a comparative study is made with a DSR protocol optimized with only LAR. The results show that UNIQUE could further reduce the overall routing overhead by as much as 58% under highly mobile conditions. With less congestion caused by routing traffic, the data packet delivery performance also improves in terms of end-to-end delay and the number of data packets successfully delivered to their destinations.

      • KCI등재

        홍경천의 흰쥐 일시적 국소뇌허혈에 대한 신경방어효과

        부영민 ( Yung Min Bu ),백선경 ( Sun Kyung Baek ),김진화 ( Zhen Hua Jin ),강동호 ( Tong Ho Kang ),노승주 ( Seung Ju Rho ),김호철 ( Ho Cheol Kim ) 대한본초학회 2004 大韓本草學會誌 Vol.19 No.2

        N/A Objectives: The root of Rhodiola sachalinensis A. bor (RS), which has been used to strengthen qi(補氣), reduce heat of lung (淸縮), nourish heart (養心), stop bleeding (止血), reduce edema(消腫) for the treatment of fatigue, amnesia, bleeding and edema. It`s flavour and channel tropism is sweet (甘), acting on the lung (肺). The purpose of the study we report here was to determine the neuroprotective effect of the roots of RS on transient focal cerebral ischemia in SD rats. Methods: The root of RS was lyophilized after extraction with 85% methanol. We occluded middle cerebral artery for 90 minutes and reperfused for 24 hours. The brain slices were stained by 2 % 2, 3, 5-triphenyltetrazolium chloride and the infarct volume was measured by graphic analyzer. Results: The root extracts of RS showed significant neuroprotective effects (100 mg/kg, p〈0.05) compared with control group. The neuroprotective efficacy was about 35%. Immunohistochemical data explained the protective effects of RS via attenuation of COX-2 induction in neocortex and inhibition of microglia activation in the penumbral region. Conclusions: The root of RS has neuroprotective effects on transient focal cerebral ischemia in Spargue-Dawley rats and the mechanism might be the attenuation of COX-2 induction and microglial activation.

      • KCI등재

        터빈 간접가열식 상압형 MCFC/가스터빈 복합시스템의 성능예측과 경제성 평가

        최주환(Joo Hwan Choi),김동섭(Tong Seop Kim),곽부호(Bu Ho Kwak) 대한기계학회 2014 大韓機械學會論文集B Vol.38 No.1

        연료전지와 가스터빈의 하이브리드 시스템의 성능은 시스템 구성방법에 따라 영향을 많이 받는다. 본 연구에서는 용융탄산염연료전지(MCFC)와 가스터빈을 터빈간접가열방식으로 모사하여 성능을 예측하였다. 하이브리드 시스템의 설계파라미터의 변화에 따른 성능의 경향을 나타내었다. 그리고 MCFC 단독 운전시의 설계조건에 미치는 영향을 최소화하는 가장 합리적이고 실현가능한 하이브리드 시스템의 설계 조건을 구현하였다. 경제성 평가를 통해 MCFC단독 시스템 대비 하이브리드 시스템의 경제적 이점을 평가하였다. The performance of fuel cell/gas turbine hybrid systems is highly affected by system configuration. In this study, the performance of a hybrid system combining a molten carbonate fuel cell (MCFC) and an indirectly fired gas turbine was predicted. Firstly, general performance trends of the hybrid system depending on major design parameters were examined. Then, the most feasible design options with the least impact on the MCFC stack design conditions were drawn. The economic advantage of the hybrid system over the basic MCFC only system was evaluated.

      • KCI등재

        Strain rate dependent behaviors of a hot isotropically processed Ti-6Al-4V: Mechanisms and material model

        Xiaohan Tang,Mingfa Ren,Fanzi Bu,Guoqing Chen,Gang Li,Tong Li 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.2

        Split-Hopkinson pressure bar (SHPB) was adopted to study the dynamic response of a specifically designed Hot isotropically processed (HIP) Casting Titanium alloy (Ti-6Al-4V). The strain-stress curves were obtained in a range of strain rate (10 -3 ~2.6×10 3 /s) to study the constitutive relationships and the Johnson-Cook model is developed to describe this dynamic constitutive law. It can be found that the static microstructure of this specific HIP casting Ti-6Al-4V is lamellar structure. When the loading increases (strain rate higher than 10 3 /s), this lamellar structure changes to basket weave structure, which further changes the mechanical strength and plasticity.

      • Diagnostic value of Thyroglobulin Measurement with Fine-needle Aspiration Biopsy for Lymph Node Metastases in Patients with a History of Differentiated Thyroid Cancer

        Zhang, Hai-Shan,Wang, Ren-Jie,Fu, Qing-Feng,Gao, Shi,Sun, Bu-Tong,Sun, Hui,Ma, Qing-Jie Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

        Purpose: The aim of this study was to evaluate the diagnostic value of FNA-Tg for detecting lymph node metastases in patients with a history of differentiated thyroid cancer (DTC). Materials and Methods: A total of 58 patients with DTC diagnosis and evidence of single or multiple suspicious cervical lymph nodes were assessed. All underwent total or near-total thyroidectomy with (35 cases) or without (23 cases) radioiodine (RAI) ablation, followed by thyroid stimulating hormone (TSH) suppression therapy. A total of 68 lymph nodes were examined by ultrasound-guided fine needle aspiration (US-FNA) for both cytological examination and FNA-Tg measurement. Serum Tg and anti-thyroglobulin antibody (TgAb) levels were also measured. Diagnostic performance including sensitivity, specificity, accuracy, positive (PPV) and negative predictive value (NPV) of FNAC and FNA-Tg were calculated and compared. The Spearman's rank correlation coefficient was used to estimate the relationship between FNA-Tg and serum TgAb. Results: The FNA-Tg levels were significantly higher with DTC metastatic lymph nodes (median 927.7 ng/mL, interquartile range 602.9 ng/mL) than non-metastatic lymph nodes (median 0.1 ng/mL, interquartile range 0.4 ng/mL) (p<0.01). Considering 1.0 ng/mL as a threshold value for FNA-Tg, the sensitivity, specificity, accuracy, PPV and NPV of FNA-Tg were 95.7%, 95.5%, 95.6%, 97.8% and 91.3%, respectively. The sensitivity and accuracy of the combination of FNAC and FNA-Tg were significantly higher than that of FNAC alone (p<0.05). The diagnostic performance of FNA-Tg was not significantly different between cases with or without RAI ablation, and the serum TgAb levels did not interfere with FNA-Tg measurements. Conclusions: Measurement of FNA-Tg is useful. The combination of FNAC and FNA-Tg is more sensitive and accurate for detecting lymph node metastases in patients with a history of DTC than FNAC alone. Serum TgAbs appear to be irrelevant for measurement of FNA-Tg.

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