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Karan Vivek,Vyas Devashish,Bohra Vikram,Huded Vikram 대한신경중재치료의학회 2019 Neurointervention Vol.14 No.2
Purpose: A safe and efficacious antiplatelet drug is needed for patients with clopidogrel resistance who undergo neuroendovascular procedures. Ticagrelor is a new reversibly binding, oral, direct-acting P2Y receptor antagonist with no known resistance. We describe our clinical experience using ticagrelor for neuroendovascular procedures in Indian patients with clopidogrel resistance at the NH Institute of Neurosciences, Narayana Health City, Bangalore. Materials and Methods: We retrospectively reviewed our endovascular procedure database for all patients with predefined clopidogrel resistance. Clopidogrel resistance was defined as P2Y12 inhibition <40%. Patients were administered ticagrelor along with aspirin prior to the procedure. Results: Of 127 patients, 32 (25%) were non-responders to clopidogrel (22 [69%] males, 10 [31%] females; median age, 54 years [range, 20–75]). All patients were treated with a 180-mg loading dose of ticagrelor, followed by 90 mg twice daily. Twenty patients (63%) underwent endovascular intervention for intracranial aneurysm, two (6%) for dissecting aneurysms, nine (28%) for stenotic lesions, and one (3%) for carotico-cavernous fistula. No patient experienced any adverse effects related to the use of Ticagrelor in the postoperative period. Conclusion: Ticagrelor is an effective alternative to clopidogrel for use in conjunction with aspirin in patients with clopidogrel resistance. None of our patients had adverse effects from ticagrelor. Drug cost, twice-daily dosing, and risk of faster platelet aggregation activation after discontinuation should be taken into consideration prior to its use in such patients.
Om Ahuja,Nisha Bohra,Asena Cetinkaya,Sushil Kumar 경북대학교 자연과학대학 수학과 2021 Kyungpook mathematical journal Vol.61 No.1
In this paper, we introduce new classes of post-quantum or (p, q)-starlike and convex functions with respect to symmetric points associated with a cardiod-shaped domain. We obtain (p, q)-Fekete-Szeg¨o inequalities for functions in these classes. We also obtain estimates of initial (p, q)-logarithmic coefficients. In addition, we get q-Bieberbachde-Branges type inequalities for the special case of our classes when p = 1. Moreover, we also discuss some special cases of the obtained results.
Ahuja, Om P.,Cetinkaya, Asena,Bohra, Nisha The Honam Mathematical Society 2020 호남수학학술지 Vol.42 No.2
We introduce a new subclass of q-bi-univalent functions of complex order related to shell-like curves connected with the Fibonacci numbers. We obtain the coefficient estimates and Fekete-Szegö inequalities for the functions belonging to this class. Relevant connections with various other known classes have been illustrated.
Pathak, Madhvesh,Samuel, Blassan,Tummalapalli, Kiran,Vuppalapati Giri, Prasanth,Bohra, Rakesh,Kim, Kap Jin Trans Tech Publications, Ltd. 2012 Advanced materials research Vol.584 No.-
<P>Titanium(IV) complexes of the type [(acac)2Ti(O-G-O] and [(acac)2Ti(OCH2CH2SH)2] {where G = (CH2)2, CH2CH(CH3), CH2CH(C2H5), CH(CH3)CH(CH3) have been synthesized in high yield by the interaction of the precursor [(acac)2Ti( OR)2] {where R = Pri , Et} with a variety of glycols and thioglycols in 1:1 and 1:2 molar ratios in refluxing benzene under anhydrous condition yield heteroleptic derivatives. On the basis of physico-chemical analyses, a cis-octahedral environment around Ti (IV) is proposed.</P>