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Liu Yan-ju,Jiang Jin-gang,Miao Feng-juan,Tao Bai-rui,Zhang Hong-lie 보안공학연구지원센터 2014 International Journal of Grid and Distributed Comp Vol.7 No.5
This paper presents a fuzzy normal estimate for mass point clouds of irregular models in reconstruction. The irregular model is complex object that some part is smooth and some parts are irregular including sharp features. Therefore, we put kNN and curvature of mass point clouds to fuzzy inference system to divide the kind of point clouds and the output of FIS can determine which part of tooth point clouds belong to. For different kinds point clouds, corresponding algorithm is given. Point clouds in the smooth area are estimated normal by PCA directly and ones in other regions of thin or sharp area are estimated by checker and attach points. This method is simpler than those complex methods used on the whole point clouds directly. The experiment results show that much time is saved and surface reconstruction is very fine than PCA and WLOP.
Study of the Ultimate Load Capacity of K-Type Tube-Gusset Plate Connections
Yan-Zhong Ju,Jia-Yang Li,De-Hong Wang,Jun-Feng Bai 한국강구조학회 2018 International Journal of Steel Structures Vol.18 No.2
In order to investigate the ultimate load capacity of K-type tube-gusset plate connections with stiff ened plate, the static tests of fi ve full-scale specimens were conducted in this study. The results indicate that the end stiff ened plate is critical for improving the load capacity of the connections. In addition, the parametric nonlinear fi nite element analysis of the K-type tube-gusset plate specimens was performed with account of such non-dimensional parameters as chord diameter-to-thickness ratio ( γ ), plate width-to-chord diameter ratio ( α ), plate thickness-to-chord thickness ratio ( 1 ), stiff ened plate thickness ( t d ), and nominal-to-yield stress ratio ( η ). The above analysis implies that the ultimate load capacity decreases with the increment of γ and increases with the increment of α and 1 , while it is only slightly aff ected by the stiff ened plate thickness. Compare the results of the fi nite element analysis with assessment by design guides existing. Based on the former results, an equation for estimating the load capacity of K-type tube-stiff ened gusset plate is proposed.
Yan, Feng,Bai, Li-Ping,Gao, Hua,Zhu, Chang-Ming,Lin, Li,Kang, Xiang-Peng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6
Aim: To investigate signaling pathways for reversal of EGF-mediated multi-drug resistance (MDR) in hepatocellular carcinoma (HCC) models. Materials and Methods: HCC MDR cell strain HepG2/adriamycin (ADM) and SMMC7721/ADM models were established using a method of exposure to medium with ADM between low and high concentration with gradually increasing concentration. Drug sensitivity and reversal of multi-drug resistance by EGF were determined and the cell cycle distribution and apoptosis were analyzed by flow cytometry. Phosphorylation of ERK1, ERK2, ERK5 and expression of Bim were detected by Western blotting. Results: The results showed that HepG2/ADM and SMMC7721/ADM cells were resistant not only to ADM, but also to multiple anticancer drugs. When used alone, EGF had no anti-tumor activity in HepG2/ADM and SMMC7721/ADM cells in vitro, while it increased the cytotoxicity of ADM. EGF induced cell apoptosis and G0/G1 phase cell cycle arrest in HepG2/ADM And SMMC7721/ADM cells, while enhancing activity of p-ERKs and up-regulated expression of BimEL. Conclusions: EGF might enhance the chemosensitivity of HepG2/ADM and SMMC7721/ADM cells via up-regulating p-ERKs and BimEL protein.
A FREE BREATHING IMPEDANCE RHEOGRAM APPARATUS MADE OF MICROPROCESSOR
Hua, Feng Jian,Chao, Zhang Xin,Wei, Zheng,Xuan, Jin Pei,Qiou, Bai Yan 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1
The impedance rheogram is a modern non-invasive method used to observe the disease of each part of the body such as heart, liver and lung etc. Because of the breathing interference effect, the patients have to hold their breathing when they are being tested by conventional impedance rheogram apparatus. It is not convenient to observe those patients who are difficult to cooperate with doctor such as children and poor-function-heart patients. Therefore, we have developed the free breathing impedance rheogram apparatus by using microprocessor, it can effectively eliminate the interference of the breathing to impedance rheogram, so that patients can be tested in the free breathing. By this way, it can not only much improve measuring accuracy, and also extend clinical service extant. The digital filtering system that we have developed by using microprocessor is used for automatically tracking variation of rhythm of the heart by specific program and filtering interference of the breathing by in-phase superposing-averaging the impendance signal of the lung in free breathing. The present artical introduces the hardware structure and main technical targets of the free breathing impedance rheogram apparatus, and provides application results for grown-up healthful persons and the patients having heart or lung problems in clinical service. The results show that the effect filtering interference of the breathing to impedance rheogram is very obvious. This technique can be used In impedance rheogram of heart and liver etc, and lays down a foundation for developing monitor in clinical service. In addition, it can also be used in studying of sport-medicine and space-medicine. This result has gotten United States Patent on Jun. 25,1991.
Jun Duan,Feng Deng,Wan-Shan Li,Xue-Lei Li,Lei-Lei Zheng,Gui-Yuan Li,Yan-Jie Bai 대한치과교정학회 2015 대한치과교정학회지 Vol.45 No.4
Objective: To compare the positions of the mandibular premolars in Angle Class I subjects according to vertical facial type. The results will provide a theoretical basis for predicting effective tooth movement in orthodontic treatment. Methods: Cephalometric parameters were determined using cone-beam computed tomography in 120 Angle Class I subjects. Subjects were categorized as short, normal, and long face types according to the Frankfort mandibular angle. Parameters indicating the position of the mandibular right premolars and the mandible were also measured. Results: The angle between the mandibular first premolar axis and buccal cortex, the distance between the root apex and buccal cortex, angle of vestibularization, arc of vestibularization, and root apex maximum movable distance were significantly greater in the short face type than in the long and norm face types. The angle between the mandibular second premolar axis and buccal cortex, the distance from root apex to buccal cortex, and the arc of vestibularization were significantly greater in the short face type than in the normal face type. Conclusions: There are significant differences in the mandibular premolar positions in Class I subjects according to vertical facial type.
Qi Fei-Yan,Zhu Zhou-Hai,Li Meng,Guan Ying,Peng Qi-Yuan,Lu She-Ming,Liu Zhi-Hua,Wang Ming-Feng,Miao Ming-Ming,Chen Zhang-Yu,Li Xue-Mei,Bai Jie,Yao Jian-Hua 한국유전학회 2022 Genes & Genomics Vol.44 No.11
Background: Smoking behavior is influenced by multiple genes, including the bitter taste gene TAS2R38. It has been reported that the correlation between TAS2R38 and smoking behavior has ethnicity-based differences. However, the TAS2R38 status in Chinese smokers is still unclear. Objective: This study aims to investigate the possible relationship between genetic variations in TAS2R38 (A49P, V262A and I296V) and smoking behaviors in the Han Chinese population. Methods: The haplotype analyses were performed and smoking behavior questionnaire was completed by 1271 individuals. Genetic association analyses for smoking behavior were analyzed using chi-square test. Further, for investigating the molecular mechanism of TAS2R38 variants effect on smoking behavior, we conducted TAS2R38-PAV and TAS2R38-AVI expression plasmids and tested the cellular calcium assay by cigarette smoke compounds stimulus in HEK293. Results: Significant associations of genetic variants within TAS2R38 were identified with smoking behavior. We found a higher PAV/PAV frequency than AVI/AVI in moderate and high nicotine dependence (FTND ≥ 4; X2 = 4.611, 1 df, p = 0.032) and strong cigarette smoke flavor intensity preference (X2 = 4.5383, 1 df, p = 0.033) in participants. Furthermore, in the in vitro cellular calcium assay, total particle matter (TPM), N-formylnornicotine and cotinine, existing in cigarette smoke, activated TAS2R38-PAV but not TAS2R38-AVI-transfected cells. Conclusion: Our data highlights that genetic variations in TAS2R38 are related to smoking behavior, especially nicotine dependence and cigarette smoke flavor intensity preference. Our findings may encourage further consideration of the taste process to identify individuals susceptible to nicotine dependence, particularly Han Chinese smokers.