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Baharlou, Solmaz,Yazdani, Mohammad Rouhollah The Korean Institute of Electrical Engineers 2017 Journal of Electrical Engineering & Technology Vol.12 No.3
In this paper, a high step-up DC-DC PWM converter with continuous input current and low voltage stress is presented for renewable energy application. The proposed converter is composed of a boost converter integrated with an auxiliary step-up circuit. The auxiliary circuit uses an additional coupled inductor and a balancing capacitor with voltage doubler and switching capacitor technique to achieve high step-up voltage gain with an appropriate switch duty cycle. The switched capacitors are charged in parallel and discharged in series by the coupled inductor, stacking on the output capacitor. In the proposed converter, the voltage stress on the main switch is clamped, so a low voltage switch with low ON resistance can be used to reduce the conduction loss which results in the efficiency improvement. A detailed discussion on the operating principle and steady-state analyses are presented in the paper. To justify the theoretical analysis, experimental results of a 200W 40/400V prototype is presented. In addition, the conducted electromagnetic emissions are measured which shows a good EMC performance.
Baharlou, Rasoul,Vasmehjani, Abbas Ahmadi,Dehghani, Ali,Ghobadifar, Mohamed Amin,Khoubyari, Mahshid The Korean Association of Immunobiologists 2014 Immune Network Vol.14 No.3
Interleukin (IL) 17 is produced by T-helper (Th) 17 with a vigorous effect on cells of the immune system playing important roles in pathogenesis of immune-mediated diseases, including autoimmune disorders and cancers. Therefore, the aim of current study was to determine the serum levels of IL-6, IL-17, and transforming growth factor beta (TGF-${\beta}$) in Iranian bladder cancer patients, and to correlate them with disease status. Blood samples were collected from 40 bladder cancer patients and 38 healthy individuals with no history of malignancies or autoimmune disorders. The serum levels of IL-6, IL-17, and TGF-${\beta}$ were measured by the enzyme-linked immunosorbent assay (ELISA). The results showed that the levels of IL-17 (p<0.0001) and TGF-${\beta}$ (p<0.0001) were significantly lower in the patients compared to the controls. No significant differences in the level of serum IL-6 (p=0.16) was observed between the patients and controls. In addition, demographic characteristics between control and patients groups were not significantly different. As most of the cases studied in this investigation were in stage I and II, it is concluded that reduced Th17-related cytokines can be used as indicators for following the course and clinical stages of bladder carcinoma progress and immune response to cancer.
Rasoul Baharlou,Abbas Ahmadi Vasmehjani1, Ali Dehghani,Ali Dehghani,Mohamed Amin Ghobadifar,Mahshid Khoubyari 대한면역학회 2014 Immune Network Vol.14 No.3
Interleukin (IL) 17 is produced by T-helper (Th) 17 with a vigorous effect on cells of the immune system playing important roles in pathogenesis of immune-mediated diseases, including autoimmune disorders and cancers. Therefore, the aim of current study was to determine the serum levels of IL-6, IL-17, and transforming growth factor beta (TGF-β) in Iranian bladder cancer patients, and to correlate them with disease status. Blood samples were collected from 40 bladder cancer patients and 38 healthy individuals with no history of malignancies or autoimmune disorders. The serum levels of IL-6, IL-17, and TGF-β were measured by the enzyme-linked immunosorbent assay (ELISA). The results showed that the levels of IL-17 (p<0.0001) and TGF-β (p<0.0001) were significantly lower in the patients compared to the controls. No significant differences in the level of serum IL-6 (p=0.16) was observed between the patients and controls. In addition, demographic characteristics between control and patients groups were not significantly different. As most of the cases studied in this investigation were in stage I and II, it is concluded that reduced Th17-related cytokines can be used as indicators for following the course and clinical stages of bladder carcinoma progress and immune response to cancer.
Solmaz Baharlou,Mohammad Rouhollah Yazdani 대한전기학회 2017 Journal of Electrical Engineering & Technology Vol.12 No.3
In this paper, a high step-up DC-DC PWM converter with continuous input current and ow voltage stress is presented for renewable energy application. The proposed converter is composed of a boost converter integrated with an auxiliary step-up circuit. The auxiliary circuit uses an additional coupled inductor and a balancing capacitor with voltage doubler and switching capacitor technique to achieve high step-up voltage gain with an appropriate switch duty cycle. The switched capacitors are charged in parallel and discharged in series by the coupled inductor, stacking on the output capacitor. In the proposed converter, the voltage stress on the main switch is clamped, so a low voltage switch with low ON resistance can be used to reduce the conduction loss which results in the efficiency improvement. A detailed discussion on the operating principle and steady-state analyses are presented in the paper. To justify the theoretical analysis, experimental results of a 200W 40/400V prototype is presented. In addition, the conducted electromagnetic emissions are measured which shows a good EMC performance.