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      • Determination of bearing type effect on elastomeric bearing selection with SREI-CAD

        Atmaca, Barbaros,Ates, Sevket Techno-Press 2017 Advances in computational design Vol.2 No.1

        The aim of this paper is to develop software for designing of steel reinforced elastomeric isolator (SREI) according to American Association for State Highway and Transportation Officials Load and Resistance Factor Design (AASHTO LRFD) Specifications. SREI is used for almost all bridge types and special structures. SREI-structures interface defines support boundary conditions and may affect the seismic performance of bridges. Seismic performance of the bridge is also affected by geometrical and materials properties of SREI. The selection of SREI is complicated process includes satisfying all the design constraints arising from code provisions and maximizing performance at the lowest possible cost. In this paper, design stage of SREI is described up to AASHTO LRFD 2012. Up to AASHTO LRFD 2012 analysis and design program of SREI performed different geometrical and material properties are created with C# object-oriented language. SREI-CAD, name of the created software, allows an accurate design for economical estimation of a SREI in a short time. To determine types of SREI effects, two different types of bearings, rectangular and circular with similar materials and dimension properties are selected as an application. Designs of these SREIs are completed with SREI-CAD. It is seen that ensuring the stability of circular elastomer bearing at the service limit state is generally complicated than rectangular bearing.

      • KCI등재

        Mirtazapine Augmentation for Selective Serotonin Reuptake Inhibitor-Induced Sexual Dysfunction: A Retropective Investigation

        Murad Atmaca,Sevda Korkmaz,Mehtap Topuz,Osman Mermi 대한신경정신의학회 2011 PSYCHIATRY INVESTIGATION Vol.8 No.1

        The aim of the present study was to retrospectively identify sexual dysfunction changes in the patients under mirtazapine-augmented serotonin reuptake inhibito (SSRI) treatment. The study comprised medical records of 20 outpatients, under mirtazapine-augmented SSRI treatment for their major depressive disorder, who had been selected among the patients that had developed sexual dysfunction to previous treatment as monotherapy, with SSRI for at least six weeks. These drugs were maintained and mirtazapine were added (15-45 mg/day). There was a significant difference in scores between baseline and week 4 or week 8 on the both Hamilton Depression Rating and Arizona Sexual Experience Scale. According to Clinical Global Impression-Improvement, 68.4% of the patients were responders. The use of low-dose mirtazapine as an add-on treatment to SSRIs appears to be an effective and well-tolerated augmenttaion for sexual dysfunction caused by SSRIs.

      • KCI등재

        Neutrophils Are Decreased in Obsessive-Compulsive Disorder: Preliminary Investigation

        Murad Atmaca,Faruk Kilic,Filiz Koseoglu,Bilal Ustundag 대한신경정신의학회 2011 PSYCHIATRY INVESTIGATION Vol.8 No.4

        Objective There has been no study in the literature evaluating total blood count in obsessive-compulsive disorder (OCD). Therefore,we performed the present study to spesifically measure serum total blood count particularly white blood cells to see whether or not its eventual alterations might have an etiopathogenetic significance in patients with OCD. Methods Total blood count was measured in thirty patients and same number of healthy controls. Additionally, all patients were assessed by Yale-Brown Obsession Compulsion Scale (Y-BOCS). Results Except for neutrophil count, there were no significant differences between the groups regarding any haematological parameter. The mean neutrophil count of the patient group was lower compared to that of the control subjects. Conclusion In conclusion, the present study suggests that neutrophil count is reduced in pure OCD patients and this finding may contribute to the role of immunological factors in the pathogenesis of OCD.

      • KCI등재후보

        Construction stage analysis of three-dimensional cable-stayed bridges

        Barbaros Atmaca,Sevket Ates 국제구조공학회 2012 Steel and Composite Structures, An International J Vol.12 No.5

        In this paper, nonlinear static analysis of three-dimensional cable stayed bridges is performed for the time dependent materials properties such as creep, shrinkage and aging of concrete and relaxation of cable. Manavgat Cable-Stayed Bridge is selected as an application. The bridge located in Antalya, Turkey, was constructed with balanced cantilever construction method. Total length of the bridge is 202 m. The bridge consists of one ë shape steel tower. The tower is at the middle of the bridge span. The construction stages and 3D finite element model of bridge are modeled with SAP2000. Large displacement occurs in these types of bridges so geometric nonlinearity is taken into consideration in the analysis by using P-Delta plus large displacement criterion. The time dependent material strength and geometric variations are included in the analysis. Two different finite element analyses carried out which are evaluated with and without construction stages and results are compared with each other. As a result of these analyses, variation of internal forces such as bending moment, axial forces and shear forces for bridge tower and displacement and bending moment for bridge deck are given with detailed. It is seen that construction stage analysis has a remarkable effect on the structural behavior of the bridge.

      • KCI등재

        Orbito-Frontal Cortex Volumes in Panic Disorder

        Murad Atmaca,Hanefi Yildirim,M. Gurkan Gurok,Muammer Akyol 대한신경정신의학회 2012 PSYCHIATRY INVESTIGATION Vol.9 No.4

        Objective Given the association between the pathophysiology of panic disorder and prefrontal cortex function, we aimed to perform a volumetric MRI study in patients with panic disorder and healthy controls focusing on the in vivo neuroanatomy of the OFC. Methods Twenty right-handed patients with panic disorder and 20 right-handed healthy control subjects were studied. The volumes of whole brain, total white and gray matters, and OFC were measured by using T1-weighted coronal MRI images, with 1.5-mm-thick slices, at 1.5T. In addition, for psychological valuation, Hamilton Depression Rating (HDRS) and Panic Agoraphobia Scales (PAS) were administered. ResultsaaUnadjusted mean volumes of the whole brain volume, total white and gray matter were not different between the patients and healthy controls while the patient group had significantly smaller left (t=-6.70, p<0.0001) and right (t=-5.86, p<0.0001) OFC volumes compared with healthy controls. Conclusion Our findings indicate an alteration of OFC morphology in the panic disorder and suggest that OFC abnormalities may be involved in the pathophysiology of panic disorder. Objective Given the association between the pathophysiology of panic disorder and prefrontal cortex function, we aimed to perform a volumetric MRI study in patients with panic disorder and healthy controls focusing on the in vivo neuroanatomy of the OFC. Methods Twenty right-handed patients with panic disorder and 20 right-handed healthy control subjects were studied. The volumes of whole brain, total white and gray matters, and OFC were measured by using T1-weighted coronal MRI images, with 1.5-mm-thick slices, at 1.5T. In addition, for psychological valuation, Hamilton Depression Rating (HDRS) and Panic Agoraphobia Scales (PAS) were administered. ResultsaaUnadjusted mean volumes of the whole brain volume, total white and gray matter were not different between the patients and healthy controls while the patient group had significantly smaller left (t=-6.70, p<0.0001) and right (t=-5.86, p<0.0001) OFC volumes compared with healthy controls. Conclusion Our findings indicate an alteration of OFC morphology in the panic disorder and suggest that OFC abnormalities may be involved in the pathophysiology of panic disorder.

      • KCI등재

        Optimization of cables size and prestressing force for a single pylon cable-stayed bridge with Jaya algorithm

        Barbaros ATMACA,Tayfun DEDE,Maksym GRZYWİNSKİ 국제구조공학회 2020 Steel and Composite Structures, An International J Vol.34 No.6

        In recent years, due to the many advantages cable-stayed bridges have often constructed in medium and long span. These advantages can be listed as an aesthetically pleasing appearance, economic and easy construction, etc. The main structural elements of cable-stayed bridges are listed as deck, pylon, cables and foundation. Perhaps one of the most vital and expensive of these structural elements is stay-cables. Stay-cables ensure the allowable displacement and distribution of bending moments along the bridge deck with prestressing force. Therefore the optimum design of the stay-cables and prestressing force are very important in achieving the performance expected from the cable-stayed bridges. This paper aims to obtain the stay-cables size and prestressing force optimization of the cable-stayed bridge. For this purpose, single pylon and fan type cable configuration Manavgat Cable-Stayed Bridge was selected as an example. The three dimensional (3D) finite element model (FEM) of the bridge was created with SAP2000. Analysis of the 3D FEM of the bridge was conducted under the different combined effects of the self-weight of the structural element, prestressing force of stay-cable and live load. Stay-cable stress and deck displacement were taken into account as constraints for the optimization problem. To optimize this existing bridge a metaheuristic algorithm named Jaya was used in the optimization process. 3D FEM of the selected bridge was repeatedly analyzed by using Open Applicable Programming Interface (OAPI) properties of SAP2000. To carry out the optimization process the developed program which integrates the Jaya algorithm and the required codes for calling SAP2000 is coded in MATLAB. At the end of the study, the total weight of the stay-cables was reduced more than 40% according to existing stay cables under loads taken into account.

      • KCI등재

        Antioxidant Effects of Sulfur-containing Amino Acids

        Gulizar Atmaca 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.5

        Sulfur is an essential element for the entire biological kingdom because of its incorporation into amino acids, proteins and other biomolecules. Sulfur atoms are also important in the iron-containing flavoenzymes. Unlike humans, plants can use inorganic sulfur to synthesize sulfur-containing amino acids. Therefore, plants are an important source of sulfur for humans. Sulfur-containing compounds are found in all body cells and are indispensable for life. Some of sulfur-containing antioxidant compounds are, cysteine, methionine, taurine, glutathione, lipoic acid, mercaptopropionylglycine, N-acetylcysteine, and the three major organosulfur compounds of garlic oil, diallylsulfide, diallyldisulfide and diallyltrisulfide. In a comparison of the structure-function relationship among these sulfur-containing antioxidant compounds, dihydrolipoic acid (the reduced form of LA) is the most effective antioxidant. Dihydrolipoic acid contains two sulfhydryl groups and can undergo further oxidation reaction to form lipoic acid. The antioxidative activities of sulfur-containing compounds follow a general trend, the more highly reduced forms are stronger antioxidants and the number of sulfur atoms determine, at least in part, their modulatory activites on the glutathione related antioxidant enzymes. In this article, the antioxidant effects and the antioxidative activities, of sulfur-containing amino acids, are reviewed. In addition, the general antioxidant effects and the structure-function relationship of some sulfur-containing compounds are also reviewed.

      • Determination of proper post-tensioning cable force of cable-stayed footbridge with TLBO algorithm

        Barbaros ATMACA 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.40 No.6

        The pleasing appearances, economic and easy construction of cable-stayed footbridges (CSFB) have made them one of the most preferred options for pedestrian traffic crossing over the highways. The basic structural members of CSFB can be sortable as a foundation, pylon, deck, and stay-cables. The stay-cable has an important role in the formation of structural integrity by ensuring that the deck and pylon work together with the help of proper post-tensioning forces (PTF) applied to them. In this study, it is aim to determine proper set of PTF with the help of the developed optimization process which provides to work together metaheuristic algorithm named Teaching-Learning-Based Optimization (TLBO) and Open Applicable Programming Interface (OAPI) properties of SAP2000 with codes created in MATLAB. In addition of this aim, the study also presents the importance of PTF for structural behavior of CSFB. TLBO algorithms use a randomly created initial population. The teacher phase and student phase are the main part of this algorithm. Five different proper sets of PTF are determined by using developed optimization process and the structural response such as displacement and internal forces of structural members of the selected CSFB compared with each other. Consequently, PTF directly affects the behavior of CSFB, as it ensures that displacements of deck and pylon remain between the acceptable limits, controls the distribution and magnitude of the internal forces for different load combinations. Furthermore, the evaluation of PTF might not have a single solution because CSFB are highly statically indeterminate so there are more different possible sets of PTFs that satisfy strength and serviceability requirements.

      • KCI등재

        Determination of minimum depth of prestressed concrete I-Girder bridge for different design truck

        Barbaros Atmaca 사단법인 한국계산역학회 2019 Computers and Concrete, An International Journal Vol.24 No.4

        The depth of superstructure is the summation of the height of girders and the thickness of the deck floor. In this study, it is aim to determine the maximum span length of girders and minimum depth of the superstructure of prestressed concrete I-girder bridge. For this purpose the superstructure of the bridge with the width of 10m and the thickness of the deck floor of 0.175m, which the girders length was changed by two meter increments between 15m and 35m, was taken into account. Twelve different girders with heights of 60, 75, 90, 100, 110, 120, 130, 140, 150, 160, 170 and 180 cm, which are frequently used in Turkey, were chosen as girder type. The analyses of the superstructure of prestressed concrete I girder bridge was conducted with I-CAD software. In the analyses AASHTO LRFD (2012) conditions were taken into account a great extent. The dead loads of the structural and non-structural elements forming the bridge superstructure, prestressing force, standard truck load, equivalent lane load and pedestrian load were taken into consideration. HL93, design truck of AASHTO and also H30S24 design truck of Turkish Code were selected as vehicular live load. The allowable concrete stress limit, the number of prestressed strands, the number of debonded strands and the deflection parameters obtained from analyses were compared with the limit values found in AASHTO LRFD (2012) to determine the suitability of the girders. At the end of the study maximum span length of girders and equation using for calculation for minimum depth of the superstructure of prestressed concrete I-girder bridge were proposed.

      • KCI등재

        Camber calculation of prestressed concrete I-Girder considering geometric nonlinearity

        Barbaros Atmaca,Şevket Ateş 사단법인 한국계산역학회 2017 Computers and Concrete, An International Journal Vol.19 No.1

        Prestressed concrete I-girders are subject to different load types at their construction stages. At the time of strand release, i.e., detensioning, prestressed concrete girders are under the effect of dead and prestressing loads. At this stage, the camber, total net upward deflection, of prestressed girder is summation of the upward deflection due to the prestressing force and the downward deflection due to dead loads. For the calculation of the upward deflection, it is generally considered that prestressed concrete I-girder behaves linear-elastic. However, the field measurements on total net upward deflection of prestressed I-girder after detensioning show contradictory results. In this paper, camber calculations with the linear-elastic beam and elastic-stability theories are presented. One of a typical precast I-girder with 120 cm height and 31.5 m effective span length is selected as a case study. 3D finite element model (FEM) of the girder is developed by SAP2000 software, and the deflections of girder are obtained from linear and nonlinear-static analyses. Only geometric nonlinearity is taken into account. The material test and field measurement of this study are performed at prestressing girder plant. The results of the linear-elastic beam and elastic-stability theories are compared with FEM results and field measurements. It is seen that the camber predicted by elastic-stability theory gives acceptable results than the linear-elastic beam theory while strand releasing.

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