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        China's Charm Defensive: Image Protection by Acquiring Mass Entertainment

        Nilgün Eliküçük Yıldırım,Mesut Aslan 인하대학교 국제관계연구소 2020 Pacific Focus Vol.35 No.1

        Focusing on discussion of China's soft power resources, this article argues that China performs two kinds of soft power strategies in developing and developed countries: offensive and defensive, respectively. While China's charm offensive aims to consolidate her comprehensive power through a development model, aid, investment, traditional culture, foreign policy, and international broadcasting in developing countries, the defensive aspect of China's soft power strategy aims to soften the rise of China with traditional culture by introducing appealing parts of Chinese culture through investments and international broadcasting in Western countries. China applies classical soft power tools in developing countries while she endeavors to protect her image in Western countries defensively. China's alternative defensive approach to soft power is mostly implemented through the acquisition of media outlets, and via the entertainment sector and gaming industry by Chinese‐owned companies. However, even in the defensive and offensive bifurcation, if charm attacks result in failure, China could turn take a defensive stance in developing countries.

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        A Comparison of the Effects of Dexamethasone and Methylprednisolone, Used on Level-3 Intensive Care COVID-19 Patients, on Mortality: A Multi-Center Retrospective Study

        Sari Ahmet,Ekinci Osman,Saraçoğlu Kemal Tolga,Balık Recep,Aslan Mesut,Balık Yelda,Önal Ceren,Aslan Murat,Cevher Semra,Parmaksız Aylin,Vatansever Şule,Çicek Münire Canan,Ayan Özge Sayın,Şensöz Çelik Ga 대한의학회 2023 Journal of Korean medical science Vol.38 No.29

        Background: Coronavirus disease 2019 (COVID-19) is often a mild disease, usually manifesting with respiratory complaints, and is sometimes mortal due to multiple organ failure. Hyperinflammation is a known COVID-19 component and is associated with organ dysfunction, disease severity and mortality. Controlling hyperinflammatory response is crucial in determining treatment direction. An important agent in providing this control is corticosteroids. This study aimed to determine whether dexamethasone and methylprednisolone, doses, administration time and duration in COVID-19 treatment are associated with improved treatment outcomes. Methods: This retrospective multicenter study was conducted with participation of 6 healthcare centers which collected data by retrospectively examining files of 1,340 patients admitted to intensive care unit due to COVID-19 between March 2020 and September 2021, diagnosed with polymerase chain reaction (+) and/or clinically and radiologically. Results: Mortality in the pulse methylprednisolone group was statistically significantly higher than that in the other 3 groups. Mortality was higher in older patients with comorbidities such as hypertension, diabetes mellitus, chronic kidney failure, coronary artery disease, and dementia. Pulse and mini-pulse steroid doses were less effective than standard methylprednisolone and dexamethasone doses, pulse steroid doses being associated with high mortality. Standard-dose methylprednisolone and dexamethasone led to similar effects, but standard dose methylprednisolone was more effective in severe patients who required mechanical ventilation (MV). Infection development was related to steroid treatment duration, not cumulative steroid dose. Conclusion: Corticosteroids are shown to be beneficial in critical COVID-19, but the role of early corticosteroids in mild COVID-19 patients remains unclear. The anti-inflammatory effects of corticosteroids may have a positive effect by reducing mortality in severe COVID-19 patients. Although dexamethasone was first used for this purpose, methylprednisolone was found to be as effective at standard doses. Methylprednisolone administered at standard doses was associated with greater PaO2/FiO2 ratios than dexamethasone, especially in the severe group requiring MV. High dose pulse steroid doses are closely associated with mortality and standard methylprednisolone dose is recommended.

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