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        Effects of Ultrasound, Laser and Exercises on Temporomandibular Joint Pain and Trismus Following Head and Neck Cancer

        Hany Mohamed Elgohary,Hadaya Mosaad Eladl,Ashraf Hassan Soliman,Elsadat Saad Soliman 대한재활의학회 2018 Annals of Rehabilitation Medicine Vol.42 No.6

        Objective To compare the effects of low intensity ultrasound (LIUS), traditional exercise therapy (TET), low level laser therapy (LLLT) and TET on temporomandibular joint (TMJ) pain and trismus following recovery from head and neck cancer (HNC). Methods Sixty participants following, who had experienced HNC, were randomly allocated to three groups of 20 people each. Each group received different therapy. Group A received LIUS and TET; group B received LLLT and TET; while group C received TET. All 60 participants were evaluated under the visual analog scale (VAS), the University of Washington Quality of Life questionnaire (UW-QOL) and the Vernier caliper scale (VCS) at the beginning of the therapies and after 4 weeks. Results ANOVA test revealed significant improvements across all three groups with outcomes of p<0.05. The results of the UW-QOL questionnaire showed a significant difference between groups A, B and C in favor of group A (p<0.05). The VAS results showed a more improvement in group A as compared to group B (p<0.05), while there was no statistical difference between groups B and C (p>0.05). The VCS results showed more improvement for the individuals in group B as compared to those in group C (p<0.05), while there was minimal difference between groups A and B (p>0.05). Conclusion The LIUS and TET are more effective than LLLT and/or TET in reducing TMJ pain and trismus following HNC.

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        Bee Honey Added to the Oral Rehydration Solution in Treatment of Gastroenteritis in Infants and Children

        Mamdouh Abdulmaksoud Abdulrhman,Mohamed Amin Mekawy,Maha Mohamed Awadalla,Ashraf Hassan Mohamed 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.3

        Among honey's benefits are its anti-inflammatory and antimicrobial effects. Because gastroenteritis is an acute inflammation of the gastrointestinal tract that may be caused by a variety of microbes, the aim of the present study was to verify whether the addition of honey in oral rehydration solution (ORS) could affect the duration of symptoms of acute gastroenteritis in infants and children. One hundred infants and children with acute gastroenteritis were randomly assigned to one of two treatment groups, each consisting of 50 patients: Group I received ORS for rehydration (control), and Group II received ORS with honey. The mean ages of patients of Groups I and II were 1.5±1.2 and 1.1±0.8 years, respectively. In the honey-treated group the frequencies of vomiting and diarrhea were significantly reduced compared to the control group (P<.001 and P<.05, respectively). Also, the recovery time, defined as the number of hours from initiation of treatment to when normal soft stools are passed, with the patient showing normal hydration and satisfactory weight gain, was significantly shortened after honey ingestion (P<.001). In conclusion, honey added to ORS promoted rehydration of the body and sped recovery from vomiting and diarrhea.

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        Protective effect of hydrogen sulfide against cold restraint stress-induced gastric mucosal injury in rats

        Esam M. Aboubakr,Ashraf Taye,Mohamed A. El-Moselhy,Magdy K. Hassan 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.12

        Hydrogen sulfide (H2S) is an endogenous gaseousmediator plays a potential role in modulating gastricinflammatory responses. However, its putative protectiverole remains to be defined. The present study aimed toevaluate role of the exogenously released and endogenouslysynthesized H2S in cold restraint stress (CRS)-induced oxidativegastric damage in rats. Rats were restrained, andmaintained at 4 C for 3 h. The H2S donor, sodium hydrosulfide(NaHS) (60 lmol/kg) was injected intraperitoneally(i.p.) before CRS. Our results revealed that NaHS pretreatmentsignificantly attenuated ulcer index, free and total acidoutput, and pepsin activity in gastric juice along withdecreased gastric mucosal carbonyl content and reactiveoxygen species production. This was accompanied byincreased gastric juice pH and mucin concentration inaddition to restoring the deficits in the gastric reduced glutathione,catalase as well as superoxide dismutase enzymeactivities. NaHS pretreatment markedly reduced the serumlevel of tumor necrosis factor (TNF-a) and myeloperoxidaseactivity compared to CRS-non-treated. Moreover, NaHSpreadministration significantly abrogated the inflammatoryand the deleterious responses of gastric mucosa in CRS. Theprotective effects of H2S were confirmed by gastric histopathologicalexamination. However, pretreatment withthe H2S-synthesizing enzyme, cystathionine-gamma-lyaseinhibitor, beta-cyano-L-alanine (50 mg/kg, i.p.) reversed thegastroprotection afforded by the endogenous H2S. Collectively, our results suggest that H2S can protect ratgastric mucosa against CRS-induced gastric ulcerationpossibly through mechanisms that involve anti-oxidant andanti-inflammatory actions alongside enhancement of gastricmucosal barrier and reduction in acid secretory parameters.

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        Effects of a Low-Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyol Diet on Symptoms of Functional Abdominal Pain in Pediatric Patients

        Yasmine Gamal Abdou El Gendy,Mohammad Ashraf Abdel Wahed,Mostafa Hussein Hassan Ragab,Yosra Mohamed Mohsen Awad 대한소아소화기영양학회 2022 Pediatric gastroenterology, hepatology & nutrition Vol.25 No.6

        Purpose: Recently, great interest has been focused on dietary fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) for the treatment of functional abdominal pain (FAP). Several meta-analyses, including those on the adult population, have been published, potentiating its role. However, pediatric studies are scarce. We aimed to evaluate the effect of a low-FODMAP diet on the severity of FAP in children. Methods: This clinical trial included 50 patients aged 3–18 years with irritable bowel syndrome and FAP that were not otherwise specified. The patients were instructed to receive a low FODMAP diet guided by a dietitian. The primary outcome was the percentage of responders after 2 months of dietary intervention compared with baseline. Other outcomes included changes in stool consistency and quality of life (QoL) scores using the KIDSCREEN-10 questionnaire, and weight-for-age z-scores. Results: After the dietary intervention, 74% of patients showed more than 30% lower pain intensity, as examined using the Wong-Baker Faces pain rating scale. Their QoL significantly improved, and patients have gained weight. Conclusion: A low FODMAP diet can improve pain intensity and QoL among children with functional abdominal pain, with no detrimental effects on body weight.

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