An Evaluation of Glucose Tolerance in Essential Hypertension

Armagan Tugrul,Sibel Guldiken,Betul Ugur-Altun,Ender Arikan 연세대학교의과대학 2009 Yonsei medical journal Vol.50 No.2

Purpose: This study aimed to determine the impaired glucose tolerance and diabetes prevalence in patients with essential hypertension (HT) and to compare the developed microvascular complications of these groups. Materials and Methods: An oral glucose tolerance test (OGTT) was performed on 338 essential hypertensive cases and glucose tolerances were classified according to ADA-2002 criteria. Results: Of the 338 cases, 32 people had diabetes (DM, 9.46%), 78 people had glucose intolerance (IGT, 23.1%), and 228 people had only hypertension but not IGT and DM (67.4%). Both the mean ages of the DM group (56.9 ± 6.7 years, p = 0.002) and IGT group (56.3 ± 8.4 years, p = 0.003) were older than the mean age of the control group (51.1 ± 6.4 years). The risk of IGT development was found to be four times greater in male cases than female cases when compared to the control group (p = 0.004, add ratio = 4.194). There were no significant differences in the body mass indexes (BMI’s), hypertension durations, and microvascular complications between the groups. Conclusion: In conclusion, the risk of IGT and DM development in hypertensive cases increases with aging and longer hypertension duration. The risk of IGT development in hypertensive cases is four times more in males. Purpose: This study aimed to determine the impaired glucose tolerance and diabetes prevalence in patients with essential hypertension (HT) and to compare the developed microvascular complications of these groups. Materials and Methods: An oral glucose tolerance test (OGTT) was performed on 338 essential hypertensive cases and glucose tolerances were classified according to ADA-2002 criteria. Results: Of the 338 cases, 32 people had diabetes (DM, 9.46%), 78 people had glucose intolerance (IGT, 23.1%), and 228 people had only hypertension but not IGT and DM (67.4%). Both the mean ages of the DM group (56.9 ± 6.7 years, p = 0.002) and IGT group (56.3 ± 8.4 years, p = 0.003) were older than the mean age of the control group (51.1 ± 6.4 years). The risk of IGT development was found to be four times greater in male cases than female cases when compared to the control group (p = 0.004, add ratio = 4.194). There were no significant differences in the body mass indexes (BMI’s), hypertension durations, and microvascular complications between the groups. Conclusion: In conclusion, the risk of IGT and DM development in hypertensive cases increases with aging and longer hypertension duration. The risk of IGT development in hypertensive cases is four times more in males.

Nutrition Practice to Alleviate the Adverse Effects of Stress on Laying Performance, Metabolic Profile and Egg Quality in Peak Producing Hens: II. The Probiotic Supplementation

Hayirli, Armagan,Esenbuga, N.,Macit, M.,Yoruk, M.A.,Yildiz, A.,Karaca, H. Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.12

In this experiment, the effects of cage density (CD) and probiotic supplementation (PS) on laying performance, metabolic profile, and egg quality in peak-producing hens were evaluated. After blocking according to the cage location, Lohman layers (n = 180, 46 wks of age) were allocated randomly to two levels of CD (540 vs. 360 $cm^2$/hen) and three levels of PS (0, 0.15, and 0.30%). Probiotic contained Enterococcus faecium culture (10${\times}$10$^9$ cfu/g). Egg production (EP) and feed consumption (FC) were measured daily; egg weight (EW) was measured bi-weekly; BW was measured before and after the experiment; and blood samples were obtained at the end of the experiment. The data were analyzed using two-way ANOVA. Increasing CD decreased FC (125.0 vs. 120.8 g/d, p<0.0001) and FCR (1.93 vs. 1.87, p<0.0001) and did not alter EP, EW, and BW. Increasing level of PS linearly decreased FC (p<0.02) and FCR (p<0.006). Averages were 123.9, 123.2, and 121.6 g/d for FC and 1.91, 1.92, and 1.86 for FCR in hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. Hens placed in high-density cages had greater serum corticosterone concentration than hens placed in normal-density cages (12.8 vs. 11.3 $\mu$g/dL, p<0.04); CD did not affect concentrations of other metabolites. Increasing level of PS linearly increased serum glucose, albumin, and creatine concentrations and quadratically increased total protein, globulin, Ca, and P concentrations. Average concentrations (mg/dL) were 260, 297, and 305 for glucose; 6.28, 8.09, and 7.58 for total protein; 1.98, 2.48, and 2.38 for albumin; 4.30, 5.62, and 5.19 for globulin; 0.40, 0.52, and 0.54 for creatine; 16.0, 16.5, and 16.3 for Ca; and 6.27, 8.14, and 7.17 for P in hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. There was no effect of CD on egg quality. Increasing level of PS linearly improved yolk color (YC) and quadratically increased albumen index (AI) and Haugh unit (HU). The mean values were 9.67, 9.75, and 10.58 for YC; 8.94, 6.93, and 8.72% for AI; and 85.6, 74.9, and 82.9 for HU for hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. There was also CD by PS effect on FC, EP, and serum glucose, total protein, albumin, globulin, creatine, Ca and P concentrations. In conclusion, increased CD partially depressed laying performance and caused stress. Probiotic supplementation improved laying performance and metabolic profile. It also partially alleviated the adverse effects of stress resulting from increased caging density.

Earthquake performance investigation of R/C residential buildings in Turkey

Kasim Armagan Korkmaz,Fuat Demir,Tugce Yenice 사단법인 한국계산역학회 2015 Computers and Concrete, An International Journal Vol.15 No.6

The aim of this study is to determine the earthquake performances of reinforced concrete (R/C) residential buildings in Turkey and to analyze the parameters that affect the performance. The performance of Turkish residential buildings, determined by their levels of damage, directly relates to their structural systems. Damage parameters observed from previous earthquakes define structural parameters selected to be used in the present study. Five different types of frame R/C buildings were modeled. For the analysis, the model buildings vary according to the number of stories, column sizes, and reinforcement and concrete strength parameters. The analyses consider gravity forces and earthquake loads through 1975 and 2007 Turkish design codes. In a total of 720 different R/C buildings were investigated for the analysis to obtain capacity curves. A performance evaluation was employed by considering the Turkish design code (TDC-2007). The current study ignores irregularities such as soft stories or short columns. The study’s analysis considers a comparison of the parameters’ influence on the structural performance of the model buildings.

Nutrition Practice to Alleviate the Adverse Effects of Stress on Laying Performance, Metabolic Profile, and Egg Quality in Peak Producing Hens: I. The Humate Supplementation

Hayirli, Armagan,Esenbuga, N.,Macit, M.,Lacin, E.,Karaoglu, M.,Karaca, H.,Yildiz, L. Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.9

This experiment was conducted to determine the effects of cage density (CD) and humate supplementation (HS) on laying performance, metabolic profile, and egg quality during the peak production period in hens. Lohman layers (n = 180, 46 wks of age) were blocked according to the location of cages and then allocated randomly to two levels of CD (4 or 6 hens per cage or 540 vs. 360 $cm^2$/hen) and three levels of HS (0, 0.15, and 0.30%). Egg production (EP) and feed consumption (FC) were measured daily; egg weight was measured bi-weekly; and BW was measured before and after the experiment. Blood and additional egg samples were obtained at the end of the experiment for determination of metabolic profile and egg quality. The data were analyzed using two-way ANOVA as repeated measures. Except for FC, CD did not affect laying performance parameters. Hens placed in high-density cages had lower FC than hens placed in normal-density cages. Increasing HS level linearly increased FC, EP, and feed conversion ratio (FCR). There was a CD by HS interaction effect on FC and EP. Hens placed in high-density cages had greater serum glucose, total protein, albumin, globulin, Ca, and P concentrations and tended to have greater serum corticosterone concentration than hens placed in normaldensity cages. Increasing HS level linearly increased serum glucose, total protein, albumin, globulin, creatine, and Ca concentrations and linearly decreased serum triglyceride and very low-density lipoprotein concentrations. There was a CD by HS interaction effect on serum glucose and albumin concentrations. There were no alterations in egg quality parameters in response to increasing CD. Albumen index and Haugh unit decreased linearly and other egg quality parameters did not change as HS level increased. In conclusion, increased caging density adversely affected metabolic profile, despite insignificantly deteriorating laying performance. Moreover, benefits from humate supplementation seem to be more noteworthy for hens housed in stressing conditions than for hens housed in standard conditions.

Seismic assessment of R/C residential buildings with infill walls in Turkey

Kasim Armagan Korkmaz,Ali Haydar Kayhan,Taner Ucar 사단법인 한국계산역학회 2013 Computers and Concrete, An International Journal Vol.12 No.5

In 1999 Marmara and 2011 Van earthquakes in Turkey, majority of the existing buildings either sustained severe damage or collapsed. These buildings include masonry infill walls in both the interior and exterior R/C frames. The material of the masonry infill is the main variant, ranging from natural stones to bricks and blocks. It is demanding to design these buildings for satisfactory structural behavior. In general, masonry infill walls are considered by its weights not by interaction between walls and frames. In this study, R/C buildings with infill walls are considered in terms of structural behavior. Therefore, 5 and 8-story R/C buildings are regarded as the representative models in the analyses. The R/C representative buildings, both with and without infill walls were analyzed to determine the effects of structural behavior change. The differences in earthquake behavior of these representative buildings were investigated to determine the effects of infill walls leading structural capacity. First, pushover curves of the representative buildings were sketched. Aftermath, time history analyses were carried out to define the displacement demands. Finally, fragility analyses were performed. Throughout the fragility analyses, probabilistic seismic assessment for R/C building structures both with and without infill walls were provided. In this study, besides the deterministic assessment methodology, a probabilistic approach was followed to define structural effect of infill walls under seismic loads.

Inhalation Therapy of Calcitonin Relieves Osteoarthritis of the Knee

Onur Armagan,Dilek Kaya Serin,Cüneyt Calisir,Ali Dokumacioglu,Merih Ozgen,Setenay Oner,Ozkan Alatas 대한의학회 2012 Journal of Korean medical science Vol.27 No.11

This study was conducted to determine if nasal salmon calcitonin has additional beneficial effects on clinical symptoms, serum NO, IL-1β, matrix metalloproteinase 3, urinary C-terminal telopeptide type II collagen (CTX-II) levels and MRI findings in knee osteoarthritis (OA) when used concomitantly with exercise therapy. Fifty female patients with knee OA were randomized into two groups. The first group (n = 30) received 200 IU/day nasal salmon calcitonin and a home exercise program; the second group (n = 20)received a home exercise program for 6 months. Compared with baseline, while significant improvements were observed in visual analogue scale (VAS), WOMAC pain, physical function scores, 20-m walking time (P < 0.001) and WOMAC stiffness score (P = 0.041) in the first group, walking and resting VAS, and WOMAC physical function scores were improved (P = 0.029) in the second group after treatment. Significantly increased levels of serum NO and urinary CTX-II (P < 0.001) and significant improvements in the area of medial femoral condyle (P < 0.05) were noted only in the first group. There were significant differences in VAS activation values (P = 0.032) and NO levels (P < 0.001) in the favor of the first group. In conclusion, nasal salmon calcitonin may have possible chondroprotective effects besides its known effects on symptoms in patients with knee OA.

Model Diet: A Simple yet Effective Model Compression for Vision Tasks

Jongmin Lee,Armagan Elibol,Nak Young Chong 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10

Computer vision coupled with machine learning algorithms has greatly helped mobile robotic platforms become more intelligent and capable of performing in the real world. Specifically, Convolutional Neural Networks (CNNs) have achieved a high accuracy on a range of visual perception tasks (e.g., object detection, classification, segmentation, and similar others). One of the bottlenecks in CNNs is their high computational requirement. This makes most of them not easily deployable on robotic platforms, since their on-board computational power is limited. Recently, Involution successfully reduced the number of parameters of CNNs by replacing all the 3 × 3 convolution kernels with involution kernels, which use 1 × 1 convolution for the kernel generation. Filter pruning methods have also successively reduced the number of parameters in CNNs. Notably, however, Involution has reshaping layers and the kernel size is unknown when loading the pre-trained model. In this paper, we propose a pruning method named Model Diet that can be applied to Involution and other CNNs. We present experimental results showing that it has better results compared with randomly initialized weights.

Performance Enhancement Step for Motion Estimation via Feature-based Image Matching

Keita Miyaura,Armagan Elibol,Nak Young Chong 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11

Most of the complicated and sophisticated tasks in visual robotics applications usually build upon the image matching step as matching images of the same scene can provide important information (e.g., camera motion). Image matching is generally done via extracting and matching some distinctive points via their feature vectors. This procedure generates some mismatched points due to imperfections. Mismatched points are called outliers and identified via probabilistic methods. Since the probabilistic methods work iteratively, they generally occupy a large portion of the computational cost of the whole image matching pipeline. In this paper, we present a simple yet efficient algorithm that is employed for eliminating the outliers aiming at reducing the total number of iterations needed in the probabilistic methods. Our method is motivated by the common way of visualizing the established matches among images. We tile images together and search for parallel lines connecting correspondences. We present extensive computational and comparative experiments using both simulated data involving along with real images and using a real dataset.

RDIU-Net: Lightweight Medical Image Segmentation Network

Juon Kurosawa,Armagan Elibol,Nak Young Chong 제어로봇시스템학회 2023 제어로봇시스템학회 국제학술대회 논문집 Vol.2023 No.10

Persona-based Dialogue Generation with Sentence Embedding for Prolonged Human-Robot Communication

Chen Yue,Armagan Elibol,Nak Young Chong 제어로봇시스템학회 2023 제어로봇시스템학회 국제학술대회 논문집 Vol.2023 No.10